Search Results - "Brunker, Patricia A.R."

Banking with precision: transfusion medicine as a potential universal application in clinical genomics by Montemayor, Celina, Brunker, Patricia A.R, Keller, Margaret A

“…PURPOSE OF REVIEWTo summarize the most recent scientific progress in transfusion medicine genomics and discuss its role within the broad genomic precision…”
Get full text

204-P: Hlafactors associated with platelet refractoriness by Brunker, Patricia A.R, Leffell, Mary S, Zachary, Andrea A

Get full text

Finding platelets: Don't let the perfect be the enemy of the good by Brunker, Patricia A. R., Pattanayak, Vikram, Mahowald, Grace K.

“…See article on page 2307–2316, in this issue…”
Get full text

Severe autoimmune hemolytic anemia following receipt of SARS‐CoV‐2 mRNA vaccine by Gadi, Sanjay R. V., Brunker, Patricia A. R., Al‐Samkari, Hanny, Sykes, David B., Saff, Rebecca R., Lo, Janet, Bendapudi, Pavan, Leaf, David E., Leaf, Rebecca Karp

“…Background Large clinical trials have demonstrated the overall safety of vaccines for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). However,…”
Get full text

Blood Group Serology and “Race”: Looking Back to Move Forward by Haspel, Richard L., Schneider, William H., Vege, Sunitha, Brunker, Patricia A.R.

“…•Race is a social, not biological, construct.•Seroanthropology is defining racial groups through blood group antigen frequencies.•Seroanthropology has been…”
Get full text

Case 34-2023: A 49-Year-Old Woman with Loss of Consciousness and Thrombocytopenia by Zachrison, Kori S., Kamalian, Shahmir, Sykes, David B., Brunker, Patricia A.R.

“…A 49-year-old woman was found unconscious at work. Evaluation was notable for aphasia, apraxia, and marked thrombocytopenia and anemia. A diagnosis was made…”
Get full text

Sociodemographic and behavioral characteristics associated with blood donation in the United States: a population‐based study by Patel, Eshan U., Bloch, Evan M., Grabowski, Mary K., Goel, Ruchika, Lokhandwala, Parvez M., Brunker, Patricia A.R., White, Jodie L., Shaz, Beth, Ness, Paul M., Tobian, Aaron A.R.

“…BACKGROUND Contemporary population‐based data on characteristics associated with blood donation in the United States (U.S.) are limited. STUDY DESIGN AND…”
Get full text

Association of blood donation with iron deficiency among adolescent and adult females in the United States: a nationally representative study by Patel, Eshan U., White, Jodie L., Bloch, Evan M., Grabowski, Mary K., Gehrie, Eric A., Lokhandwala, Parvez M., Brunker, Patricia A. R., Goel, Ruchika, Shaz, Beth H., Ness, Paul M., Tobian, Aaron A. R.

“…BACKGROUND Blood donation results in a loss of iron stores, which is particularly concerning for young female blood donors. This study examines the association…”
Get full text

Unmasking delayed hemolytic transfusion reactions in patients with sickle‐cell disease: Challenges and opportunities for improvement by Covington, Mischa L., Cone‐Sullivan, Jensyn K., Andrzejewski, Chester, Lu, Wen, Thomasson, Reggie R., O'Brien, Kerry, Brunker, Patricia A. R., Stowell, Sean R.

Get full text

Recombinant ADAMTS13 for Immune Thrombotic Thrombocytopenic Purpura by Bendapudi, Pavan K., Foy, Brody H., Mueller, Sarah B., Liu, Jun, Feingold, Louis M., Burke, Kristen E., Cruz, Wendy, Chen, Maria Y., Lau, Emily S., Goldberg, Rachel L., Tatake, Ishan, Wilkinson, Shelby C., Carney, Brian J., Stone, James R., Park, Doyun, Avelino, Alzira R., Hassan, Sajjad, Andrzejewski, Chester, Ruby, Kristen N., Friedman, Kenneth D., Brunker, Patricia A.R., Leaf, Rebecca K., Higgins, John, Dzik, Walter H., Stefely, Jonathan A., Makar, Robert S.

“…In patients with immune thrombotic thrombocytopenic purpura (iTTP), autoantibodies against the metalloprotease ADAMTS13 lead to catastrophic microvascular…”
Get full text

Secondary bacterial culture of platelets to mitigate transfusion‐associated sepsis: A 3‐year analysis at a large academic institution by Fenwick, Alexander J., Gehrie, Eric A., Marshall, Christi E., Tobian, Aaron A. R., Shrestha, Ruchee, Kacker, Seema, Brunker, Patricia A. R., Shifflett, Lisa, Carroll, Karen C., Gozelanczyk, Donna, Goel, Ruchika, Ness, Paul M., Bloch, Evan M.

“…Background In 2019, the United States Food and Drug Administration published its final recommendations to mitigate bacterial contamination of platelets. We…”
Get full text

Consider the source: the importance of including all transfused products and exposures in red blood cell alloimmunization research by Brunker, Patricia A.R.

Get full text

Hemostatic profile and safety of pooled cryoprecipitate up to 120 hours after thawing by Lokhandwala, Parvez M., O'Neal, Adrian, Patel, Eshan U., Brunker, Patricia A. R., Gehrie, Eric A., Zheng, Gang, Kickler, Thomas S., Ness, Paul M., Tobian, Aaron A. R.

“…BACKGROUND AABB standards state that cryoprecipitate should be transfused within 4 to 6 hours after thawing. We evaluated coagulation factor levels and…”
Get full text

An open‐source python library for detection of known and novel Kell, Duffy and Kidd variants from exome sequencing by Montemayor, Celina, Simone, Alexandra, Long, James, Montemayor, Oscar, Delvadia, Bhavesh, Rivera, Robert, Lewis, Katie L, Shahsavari, Shahin, Gandla, Divya, Dura, Katherine, Krishnan, Uma S, Wendzel, Nena C, Elavia, Nasha, Grissom, Spencer, Karagianni, Panagiota, Bueno, Marina, Loy, Debrean, Cacanindin, Rizaldi, McLaughlin, Steven, Tynuv, Maxim, Brunker, Patricia A R, Roback, John, Adams, Sharon, Smith, Harold, Biesecker, Leslie, Klein, Harvey G

“…Background and objectives Next generation sequencing (NGS) has promising applications in transfusion medicine. Exome sequencing (ES) is increasingly used in…”
Get full text

Immunohematology and Transfusion Support of a Patient with Acute Myeloid Leukemia and an Anti-Vel by O'Brien, Jennifer J., Bade, Najeebah A., Lee-Stroka, Agnes Hallie, Learn, Sakhone B., Nance, Sandra, Tremblay, Christine A., McGann, Heather L., Brunker, Patricia A.R., Hardy, Nancy M., Baer, Maria R., Fontaine, Magali J.

“…Background Transfusion support of cancer patients presenting with red blood cell (RBC) antibodies against high-incidence antigens is a challenge for…”
Get full text

Convalescent transfusion for pandemic influenza: preparing blood banks for a new plasma product? by Leider, Jonathon P., Brunker, Patricia A.R., Ness, Paul M.

“…Due to the potential of a severe pandemic to limit efficacy or availability of medical countermeasures, some researchers have begun a search for new…”
Get full text

SNP Genotyping and LD Testing in ERMAP: Revealing Scianna Blood Group Diversity in NIH Blood Donors by Follit, Courtney A., Brunker, Patricia A.R., Flegel, Willy A.

“…Abstract 2322 The Scianna blood group system has been implicated in cases of hemolytic disease of the fetus and newborn and the detection of antibodies to rare…”
Get full text

Modeling alloantibody formation to high-incidence red blood cell antigens in immune responders using genotypic data by Brunker, Patricia A R, Ravindran, Keerthana, Shirey, R S

“…Alloimmunization to red blood cell antigens is unpredictable and poorly understood. Patients who are negative for high-incidence antigens (HIAs) are at risk…”
Get more information

Chimerism in transfusion medicine: The grandmother effect revisited by Brunker, Patricia AR

“…Transfusion therapy is complicated by the production of alloantibodies to antigens present in the donor and lacking in the recipient through the…”
Get full text

Identification of An Atypical Paraprotein with Inconsistent M-Spike Quantitation in Four Patients with Waldenstrom's Macroglobulinemia by Brunker, Patricia A.R., Glidden, Elizabeth, Ghobrial, Irene M., Lindeman, Neal I.

“…The densitometric quantitation of the M-spike in patients with a monoclonal gammopathy is a standard method used to monitor diseases such as multiple myeloma…”
Get full text