Search Results - "Bruni, Robert"

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    A new class of antimalarial drugs: derivatives of benzothiopyrans by Razdan, Raj K, Bruni, Robert J, Mehta, Avinash C, Weinhardt, Klaus K, Papanastassiou, Zinon B

    Published in Journal of medicinal chemistry (01-07-1978)
    “…Plasmodium berghei, mice, synthesis and antimalarial action of series of substituted benzothiopyrans, structure-activity relationships…”
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    Journal Article
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    Aromatic hydroxylation of ellipticine in rats: lack of an NIH shift by Reinhold, V N, Bruni, R J

    Published in Biomedical mass spectrometry (01-12-1976)
    “…Metabolites of the antitumor agent, elipticine (NSC) 71795), are mainly secreted in rat bile as two conjugates of hydroxylated elipticine. The possible…”
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    A phase I trial of combination therapy with continuous-infusion PALA and continuous-infusion 5-FU by Weiss, G R, Ervin, T J, Meshad, M W, Schade, D, Branfman, A R, Bruni, R J, Chadwick, M, Kufe, D W

    Published in Cancer chemotherapy and pharmacology (01-01-1982)
    “…Thirty-four patients were treated with N-(phosphonacetyl)-L-aspartate (PALA) at a dose of 850 mg/m2/day x 5 by continuous intravenous infusion (days 1-5) and…”
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    Journal Article