Search Results - "Bruni, Cassi M."

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis by Seidman, Jason S., Troutman, Ty D., Sakai, Mashito, Gola, Anita, Spann, Nathanael J., Bennett, Hunter, Bruni, Cassi M., Ouyang, Zhengyu, Li, Rick Z., Sun, Xiaoli, Vu, BaoChau T., Pasillas, Martina P., Ego, Kaori M., Gosselin, David, Link, Verena M., Chong, Ling-Wa, Evans, Ronald M., Thompson, Bonne M., McDonald, Jeffrey G., Hosseini, Mojgan, Witztum, Joseph L., Germain, Ronald N., Glass, Christopher K.

“…Tissue-resident and recruited macrophages contribute to both host defense and pathology. Multiple macrophage phenotypes are represented in diseased tissues,…”
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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity by Sakai, Mashito, Troutman, Ty D., Seidman, Jason S., Ouyang, Zhengyu, Spann, Nathanael J., Abe, Yohei, Ego, Kaori M., Bruni, Cassi M., Deng, Zihou, Schlachetzki, Johannes C.M., Nott, Alexi, Bennett, Hunter, Chang, Jonathan, Vu, BaoChau T., Pasillas, Martina P., Link, Verena M., Texari, Lorane, Heinz, Sven, Thompson, Bonne M., McDonald, Jeffrey G., Geissmann, Frederic, Glass, Christopher K.

“…Tissue environment plays a powerful role in establishing and maintaining the distinct phenotypes of resident macrophages, but the underlying molecular…”
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Novel Combination Strategies to Enhance Immune Checkpoint Inhibition in Cancer Immunotherapy: A Narrative Review by Hermel, Jonathan A., Bruni, Cassi M., Sigal, Darren S.

“…Programmed cell death protein-1 (PD-1) is an immune checkpoint receptor that induces and maintains tolerance of T cells, invariant natural killer T (iNKT)…”
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Exploiting altered enhancer landscapes to decode pathogenic changes in gene expression of diverse hepatic macrophages by Troutman, Ty Dale, Seidman, Jason S., Sakai, Mashito, Gola, Anita, Ouyang, Zhengyu, Spann, Nathanael J., Bruni, Cassi M., Bennett, Hunter, Ego, Kaori, Vu, BaoChau, Sun, Xiaoli, Pasillas, Martina, Witztum, Joseph L., Germain, Ronald N., Glass, Christopher K.

“…Abstract Kupffer cells have specialized roles supporting the environment of the liver during homeostasis and disease. However, the key regulatory elements…”
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Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis by Seidman, Jason S., Troutman, Ty D., Sakai, Mashito, Gola, Anita, Spann, Nathanael J., Bennett, Hunter, Bruni, Cassi M., Ouyang, Zhengyu, Li, Rick Z., Sun, Xiaoli, Vu, BaoChau T., Pasillas, Martina P., Ego, Kaori M., Gosselin, David, Link, Verena M., Chong, Ling-Wa, Evans, Ronald M., Thompson, Bonne M., McDonald, Jeffrey G., Hosseini, Mojgan, Witztum, Joseph L., Germain, Ronald N., Glass, Christopher K.

“…Tissue resident and recruited macrophages contribute to both host defense and pathology. Multiple macrophage phenotypes are represented in diseased tissues,…”
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Deciphering liver environmental signaling pathways for Kupffer cell identity by Sakai, Mashito, Troutman, Ty Dale, Seidman, Jason S., Ouyang, Zhengyu, Spann, Nathanael J., Abe, Yohei, Ego, Kaori, Bruni, Cassi M., Schlachetzki, Johannes C. M., Nott, Alexi, Bennett, Hunter, Chang, Jonathan, Vu, BaoChau T., Pasillas, Martina, Link, Verena M., Texari, Lorane, Heinz, Sven, Glass, Christopher K.

“…Abstract Functional specialization of tissue resident macrophages occurs through environmental signals controlling activity and/or expression of transcription…”
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