Search Results - "Brunetta, Enrico"
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Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19
Published in Nature immunology (01-01-2021)“…Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of…”
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2
Early Predictors of Clinical Deterioration in a Cohort of 239 Patients Hospitalized for Covid-19 Infection in Lombardy, Italy
Published in Journal of clinical medicine (20-05-2020)“…We described features of hospitalized Covid-19 patients and identified predictors of clinical deterioration. We included patients consecutively admitted at…”
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3
The biology, pathogenetic role, clinical implications, and open issues of serum anti-neutrophil cytoplasmic antibodies
Published in Autoimmunity reviews (01-03-2021)“…Anti-neutrophil cytoplasmic antibodies (ANCA) are a group of autoantibodies, predominantly IgG, involved in the pathogenesis of several autoimmune disorders,…”
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4
Biomarkers and Diagnostic Testing for Renal Disease in Sjogren's Syndrome
Published in Frontiers in immunology (17-09-2020)“…Primary Sjogren's syndrome (pSS) is an autoimmune disorder in which lymphocytic infiltration leads to lacrimal and salivary glands dysfunction, which results…”
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5
The X chromosome and the sex ratio of autoimmunity
Published in Autoimmunity reviews (01-05-2012)“…Abstract The number of human conditions that are currently considered to be autoimmune diseases (AID) has been steadily growing over the past decades and it is…”
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6
Pathologic natural killer cell subset redistribution in HIV-1 infection: new insights in pathophysiology and clinical outcomes
Published in Journal of leukocyte biology (01-12-2010)“…Review discusses the clinical significance of the pathologic NK cell subset redistribution during HIV‐1 infection. Several lines of evidence indicate that the…”
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ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives
Published in Journal of immunology research (01-01-2019)“…The purpose of this paper is to collect and summarize all evidences relating to an association between ANCA-associated vasculitides (AAVs) and hematologic…”
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Cutting Edge: Biomarkers for Chronic Spontaneous Urticaria
Published in Journal of immunology research (01-01-2018)“…Chronic spontaneous urticaria (CSU) is defined by the appearance of wheals and a variable presence of angioedema which persists for at least 6 weeks. It…”
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9
Can strenuous exercise harm the heart? Insights from a study of cardiovascular neural regulation in amateur triathletes
Published in PloS one (07-05-2019)“…Regular exercise is recommended to improve the cardiovascular risk profile. However, there is growing evidence that extreme volumes and intensity of long-term…”
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10
Serum ANCA and Overall Mortality: A 10-Year Retrospective Cohort Study on 1,024 Italian Subjects
Published in Frontiers in immunology (10-09-2021)“…Antineutrophil cytoplasmic antibodies (ANCA) are primarily involved in the pathogenesis of ANCA-associated vasculitides (AAV). However, ANCA may also be…”
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11
Autonomic Abnormalities in Patients With Primary Sjogren’s Syndrome – Preliminary Results
Published in Frontiers in physiology (27-08-2019)“…Primary Sjögren’s syndrome (pSS) is an autoimmune disease affecting exocrine glands and extra-glandular organs. There are conflicting reports on the presence…”
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12
Learning Analytics Applied to Clinical Diagnostic Reasoning Using a Natural Language Processing-Based Virtual Patient Simulator: Case Study
Published in JMIR medical education (03-03-2022)“…Virtual patient simulators (VPSs) log all users' actions, thereby enabling the creation of a multidimensional representation of students' medical knowledge…”
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13
The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19
Published in EBioMedicine (01-10-2024)Get full text
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14
PFAPA syndrome and Behçet’s disease: a comparison of two medical entities based on the clinical interviews performed by three different specialists
Published in Clinical rheumatology (01-02-2016)“…The pediatric syndrome characterized by periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) and adult Behçet’s disease share some…”
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15
Engagement of Siglec-7 receptor induces a pro-inflammatory response selectively in monocytes
Published in PloS one (28-09-2012)“…Sialic acid binding immunoglobulin-like lectin-7 (Siglec-7) is a trans-membrane receptor carrying immunoreceptor tyrosine based inhibitory motifs (ITIMs) and…”
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16
Incidence and predictors of post‐surgery atrial fibrillation occurrence: A cohort study in 53,387 patients
Published in Journal of arrhythmia (01-08-2024)“…Introduction Atrial fibrillation (AF) represents the most common arrhythmia in the postoperative setting. We aimed to investigate the incidence of…”
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Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals
Published in PLoS pathogens (01-07-2008)“…Understanding the cellular mechanisms that ensure an appropriate innate immune response against viral pathogens is an important challenge of biomedical…”
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18
HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response
Published in PLoS pathogens (01-10-2009)“…Natural killer (NK) cells are stimulated by ligands on virus-infected cells. We have recently demonstrated that NK cells respond to human immunodeficiency…”
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Hyperforin blocks neutrophil activation of matrix metalloproteinase-9, motility and recruitment, and restrains inflammation-triggered angiogenesis and lung fibrosis
Published in The Journal of pharmacology and experimental therapeutics (01-05-2007)“…Hyperforin (Hyp), a polyphenol-derivative of St. John's wort (Hypericum perforatum), has emerged as key player not only in the antidepressant activity of the…”
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Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease
Published in Journal of leukocyte biology (01-01-2008)“…Hyperforin (Hyp) is an active compound contained in the extract of Hypericum perforatum, well known for its antidepressant activity. However, Hyp has been…”
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