Search Results - "Brune, Jan C"
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High-Speed Fluorescence Imaging Corroborates Biological Data on the Influence of Different Nozzle Types on Cell Spray Viability and Formation
Published in Journal of functional biomaterials (14-05-2024)“…Treating severe dermal disruptions often presents significant challenges. Recent advancements have explored biological cell sprays as a promising treatment,…”
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First Human Leucocyte Antigen (HLA) Response and Safety Evaluation of Fibrous Demineralized Bone Matrix in a Critical Size Femoral Defect Model of the Sprague-Dawley Rat
Published in Materials (13-07-2020)“…Treatment of large bone defects is one of the great challenges in contemporary orthopedic and traumatic surgery. Grafts are necessary to support bone healing…”
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One Stage Masquelets Technique: Evaluation of Different Forms of Membrane Filling with and without Bone Marrow Mononuclear Cells (BMC) in Large Femoral Bone Defects in Rats
Published in Cells (Basel, Switzerland) (30-04-2023)“…The classic two-stage masquelet technique is an effective procedure for the treatment of large bone defects. Our group recently showed that one surgery could…”
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Influence of peracetic acid-ethanol sterilisation on the biomechanical properties of human meniscus transplants
Published in Journal of experimental orthopaedics (05-03-2021)“…Purpose Meniscus allograft transplantation (MAT) is a possible treatment for patients suffering with pain after meniscectomy. Here, peracetic acid (PAA)…”
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Analysis of the Ability of Different Allografts to Act as Carrier Grafts for Local Drug Delivery
Published in Journal of functional biomaterials (01-06-2023)“…Bone defects and infections pose significant challenges for treatment, requiring a comprehensive approach for prevention and treatment. Thus, this study sought…”
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Fibrous Demineralized Bone Matrix (DBM) Improves Bone Marrow Mononuclear Cell (BMC)-Supported Bone Healing in Large Femoral Bone Defects in Rats
Published in Cells (Basel, Switzerland) (19-05-2021)“…Regeneration of large bone defects is a major objective in trauma surgery. Bone marrow mononuclear cell (BMC)-supported bone healing was shown to be efficient…”
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The Induced Membrane Technique-The Filling Matters: Evaluation of Different Forms of Membrane Filling with and without Bone Marrow Mononuclear Cells (BMC) in Large Femoral Bone Defects in Rats
Published in Biomedicines (10-03-2022)“…The Masquelet technique is used to treat large bone defects; it is a two-stage procedure based on an induced membrane. To improve the induced membrane process,…”
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Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells
Published in BMJ open respiratory research (2014)“…Background Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future…”
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Bone allografts combined with adipose-derived stem cells in an optimized cell/volume ratio showed enhanced osteogenesis and angiogenesis in a murine femur defect model
Published in Journal of molecular medicine (Berlin, Germany) (01-10-2019)“…Critical sized defects, especially in long bones, pose one of the biggest problems in orthopedic surgery. By definition, these defects do not heal without…”
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Anatomical acromioclavicular joint stabilization with chemically sterilized tendon allografts: A retrospective study
Published in Shoulder & elbow (01-08-2023)“…Background The purpose of this retrospective study was to analyze whether chemically sterilized tendon allografts perform as well as other non-sterilized…”
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Anti-endotoxic and antibacterial effects of a dermal substitute coated with host defense peptides
Published in Biomaterials (01-06-2015)“…Abstract Biomaterials used during surgery and wound treatment are of increasing importance in modern medical care. In the present study we set out to evaluate…”
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Comparison of three different types of scaffolds preseeded with human bone marrow mononuclear cells on the bone healing in a femoral critical size defect model of the athymic rat
Published in Journal of tissue engineering and regenerative medicine (01-03-2018)“…Large bone defects often pose major difficulties in orthopaedic surgery. The application of long‐term cultured stem cells combined with a scaffold lead to a…”
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Peracetic acid sterilized tendon and ligament allografts for knee reconstruction : For anterior cruciate ligament (ACL), posterior cruciate ligament (PCL) and complex knee surgery
Published in Orthopädie (Heidelberg, Germany) (01-05-2024)“…The use of allografts and autografts has been met with mixed views on whether allografts are a suitable alternative to autografts. We aimed to investigate if…”
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Characterization of Bone Marrow Mononuclear Cells on Biomaterials for Bone Tissue Engineering In Vitro
Published in BioMed research international (01-01-2015)“…Bone marrow mononuclear cells (BMCs) are suitable for bone tissue engineering. Comparative data regarding the needs of BMC for the adhesion on biomaterials and…”
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Mesenchymal stromal cells from primary osteosarcoma are non‐malignant and strikingly similar to their bone marrow counterparts
Published in International journal of cancer (15-07-2011)“…Mesenchymal stromal cells (MSC) are multipotent cells that can be isolated from a number of human tissues. In cancer, MSC have been implicated with tumor…”
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Characterization of bone marrow-derived mesenchymal stromal cells (MSC) based on gene expression profiling of functionally defined MSC subsets
Published in Cytotherapy (Oxford, England) (01-01-2009)“…Background aims Human mesenchymal stromal cells (MSC) are promising candidates for cell therapy because of their intriguing properties (high proliferation and…”
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Whither Advanced Therapy Medicinal Products?
Published in Transfusion medicine and hemotherapy (01-12-2013)Get full text
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Corrigendum to “Characterization of Bone Marrow Mononuclear Cells on Biomaterials for Bone Tissue Engineering In Vitro”
Published in BioMed research international (01-01-2015)“…In the paper titled “Characterization of Bone Marrow Mononuclear Cells on Biomaterials for Bone Tissue Engineering In Vitro,” [1] there was an error in the…”
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Prospective Identification and Characterization of Human Mesenchymal Stem Cell Subpopulations
Published in Blood (16-11-2006)“…Mesenchymal stem cells (MSC) are multipotent cells that readily differentiate into a variety of cell types including osteoblasts, chondrocytes, and adipocytes…”
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