Search Results - "Bruna, K"

Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation by Muraro, Stéfanie P., De Souza, Gabriela F., Gallo, Stephanie W., Da Silva, Bruna K., De Oliveira, Sílvia D., Vinolo, Marco Aurélio R., Saraiva, Elvira M., Porto, Bárbara N.

“…Respiratory syncytial virus (RSV) is a major cause of diseases of the respiratory tract in young children and babies, being mainly associated with…”
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Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males by Abou-El-Hassan, Hadi, Rezende, Rafael M., Izzy, Saef, Gabriely, Galina, Yahya, Taha, Tatematsu, Bruna K., Habashy, Karl J., Lopes, Juliana R., de Oliveira, Gislane L. V., Maghzi, Amir-Hadi, Yin, Zhuoran, Cox, Laura M., Krishnan, Rajesh, Butovsky, Oleg, Weiner, Howard L.

“…Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and adaptive immune responses play an important role in the pathogenesis…”
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High-yield production of rod-like and spherical nanocellulose by controlled enzymatic hydrolysis of mechanically pretreated cellulose by Dias, Isabella K.R., Lacerda, Bruna K., Arantes, Valdeir

“…In this study, a simple and scalable mechanical pretreatment was evaluated as means of enhancing the accessibility of cellulose fibers, with the objective of…”
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Blue-Green Iridium(III) Emitter and Comprehensive Photophysical Elucidation of Heteroleptic Cyclometalated Iridium(III) Complexes by Zanoni, Kassio P. S, Kariyazaki, Bruna K, Ito, Akitaka, Brennaman, M. Kyle, Meyer, Thomas J, Murakami Iha, Neyde Y

“…Synthesis and photophysical properties of the highly emissive complex [Ir­(Fppy)2(dmb)]+ are reported along with those of additional heteroleptic…”
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Déjà vu: Stimulating open drug discovery for SARS-CoV-2 by Ekins, Sean, Mottin, Melina, Ramos, Paulo R.P.S., Sousa, Bruna K.P., Neves, Bruno Junior, Foil, Daniel H., Zorn, Kimberley M., Braga, Rodolpho C., Coffee, Megan, Southan, Christopher, Puhl, Ana C., Andrade, Carolina Horta

“…•We describe our prior efforts in open drug discovery for Ebola and Zika virus.•We summarize the current literature for severe acute respiratory syndrome…”
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Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice by Paes-Colli, Yolanda, Aguiar, Andrey F L, Isaac, Alinny Rosendo, Ferreira, Bruna K, Campos, Raquel Maria P, Trindade, Priscila Martins Pinheiro, de Melo Reis, Ricardo Augusto, Sampaio, Luzia S

“…Historically, Cannabis is one of the first plants to be domesticated and used in medicine, though only in the last years the amount of Cannabis-based products…”
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Cannabinoid Therapeutics in Chronic Neuropathic Pain: From Animal Research to Human Treatment by Campos, Raquel Maria P, Aguiar, Andrey F L, Paes-Colli, Yolanda, Trindade, Priscila Martins Pinheiro, Ferreira, Bruna K, de Melo Reis, Ricardo A, Sampaio, Luzia S

“…Despite the importance of pain as a warning physiological system, chronic neuropathic pain is frequently caused by damage in the nervous system, followed by…”
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High intensity interval exercise decreases IL-8 and enhances the immunomodulatory cytokine interleukin-10 in lean and overweight–obese individuals by Dorneles, Gilson P., Haddad, Desirée O., Fagundes, Viviane O., Vargas, Bruna K., Kloecker, Alana, Romão, Pedro R.T., Peres, Alessandra

“…•Obese individuals exhibit a low grade systemic inflammatory profile.•High intensity interval exercise (HIIE) decreased IL-8 levels in lean and obese.•HIIE…”
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Nasal administration of anti-CD3 monoclonal antibody ameliorates disease in a mouse model of Alzheimer's disease by Lopes, Juliana R, Zhang, Xiaoming, Mayrink, Julia, Tatematsu, Bruna K, Guo, Lydia, LeServe, Danielle S, Abou-El-Hassan, Hadi, Rong, Felipe, Dalton, Maria J, Oliveira, Marilia G, Lanser, Toby B, Liu, Lei, Butovsky, Oleg, Rezende, Rafael M, Weiner, Howard L

“…Emerging evidence suggests that dysregulation of neuroinflammation, particularly that orchestrated by microglia, plays a significant role in the pathogenesis…”
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Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate by Freire, Marjorie C. L. C., Basso, Luis G. M., Mendes, Luis F. S., Mesquita, Nathalya C. M. R., Mottin, Melina, Fernandes, Rafaela S., Policastro, Lucca R., Godoy, Andre S., Santos, Igor A., Ruiz, Uriel E. A., Caruso, Icaro P., Sousa, Bruna K. P., Jardim, Ana C. G., Almeida, Fabio C. L., Gil, Laura H. V. G., Andrade, Carolina H., Oliva, Glaucius

“…Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The…”
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γδ T Cell-Secreted XCL1 Mediates Anti-CD3-Induced Oral Tolerance by Rezende, Rafael M, Nakagaki, Brenda N, Moreira, Thais G, Lopes, Juliana R, Kuhn, Chantal, Tatematsu, Bruna K, Boulenouar, Selma, Maghzi, Amir-Hadi, Rubino, Stephen, Menezes, Gustavo B, Chitnis, Tanuja, Weiner, Howard L

“…Oral tolerance is defined as the specific suppression of cellular and/or humoral immune responses to an Ag by prior administration of the Ag through the oral…”
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Ginkgo biloba extract modulates astrocytic and microglial recruitment in the hippocampus and hypothalamus of menopause-induced ovariectomized rats by Machado, Meira M.F., Ático, Esther M., Banin, Renata M., Hirata, Bruna K.S., Kempe, Paula R.G., Pedroso, Amanda P., Thomaz, Fernanda M., Oyama, Lila M., Ribeiro, Eliane B., Bueno, Allain A., Cerutti, Suzete M., Telles, Mônica M.

“…Changes in steroid hormone levels associated with menopause are known to affect body composition, with increased accumulation of visceral fat and impaired…”
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Omega-3 fatty acid supplementation can prevent changes in mitochondrial energy metabolism and oxidative stress caused by chronic administration of L-tyrosine in the brain of rats by Carvalho-Silva, Milena, Gomes, Lara M., Gomes, Maria L., Ferreira, Bruna K., Schuck, Patricia F., Ferreira, Gustavo C., Dal-Pizzol, Felipe, de Oliveira, Jade, Scaini, Giselli, Streck, Emilio L.

“…Deficiency of hepatic enzyme tyrosine aminotransferase characterizes the innate error of autosomal recessive disease Tyrosinemia Type II. Patients may develop…”
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Natural history predicts patterns of thermal vulnerability in amphibians from the Atlantic Rainforest of Brazil by Carilo Filho, Leildo M., Carvalho, Bruno T., Azevedo, Bruna K. A., Gutiérrez‐Pesquera, Luis M., Mira‐Mendes, Caio V., Solé, Mirco, Orrico, Victor G. D.

“…In the Brazilian Atlantic Rainforest (AF), amphibians (625 species) face habitat degradation leading to stressful thermal conditions that constrain animal…”
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Gamma-delta T cells suppress microbial metabolites that activate striatal neurons and induce repetitive/compulsive behavior in mice by Cox, Laura M., Tatematsu, Bruna K., Guo, Lydia, LeServe, Danielle S., Mayrink, Julia, Oliveira, Marilia G., Donnelly, Dustin, Fonseca, Roberta C., Lemos, Luisa, Lanser, Toby B., Rosa, Ana C., Lopes, Juliana R., Schwerdtfeger, Luke A., Ribeiro, Gabriela F.C., Lobo, Eduardo L.C., Moreira, Thais G., Oliveira, Andre G., Weiner, Howard L., Rezende, Rafael M.

“…•γδ T cells regulate the gut microbiota.•In the absence of γδ T cells, mice develop a microbial dysbiosis with the growth of microbes involved in the…”
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Gamma-delta T cells modulate the microbiota and fecal micro-RNAs to maintain mucosal tolerance by Rezende, Rafael M, Cox, Laura M, Moreira, Thais G, Liu, Shirong, Boulenouar, Selma, Dhang, Fyonn, LeServe, Danielle S, Nakagaki, Brenda N, Lopes, Juliana R, Tatematsu, Bruna K, Lemos, Luisa, Mayrink, Julia, Lobo, Eduardo L C, Guo, Lydia, Oliveira, Marilia G, Kuhn, Chantal, Weiner, Howard L

“…Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition. Little is…”
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Antibody Therapy for the Control of Viral Diseases: An Update by Dibo, Miriam, Battocchio, Eduardo C, Dos Santos Souza, Lucas M, da Silva, Matheus D Veloso, Banin-Hirata, Bruna K, Sapla, Milena M M, Marinello, Poliana, Rocha, Sérgio P D, Faccin-Galhardi, Lígia C

“…The epidemiological impact of viral diseases, combined with the emergence and reemergence of some viruses, and the difficulties in identifying effective…”
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School-based obesity interventions in the metropolitan area of Rio De Janeiro, Brazil: pooled analysis from five randomised studies by Rodrigues, Renata da R. M., Hassan, Bruna K., Sgambato, Michele R., Souza, Bárbara da S. N., Cunha, Diana B., Pereira, Rosangela A., Yokoo, Edna M., Sichieri, Rosely

“…School-based studies, despite the large number of studies conducted, have reported inconclusive results on obesity prevention. The sample size is a major…”
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Comparison of generational effect on proteins and metabolites in non-transgenic and transgenic soybean seeds through the insertion of the cp4-EPSPS gene assessed by omics-based platforms by de Campos, Bruna K., Galazzi, Rodrigo M., dos Santos, Bruna M., Balbuena, Tiago S., dos Santos, Fábio N., Mokochinski, João B., Eberlin, Marcos N., Arruda, Marco A.Z.

“…This work evaluates different generations of transgenic (cp4-EPSPS gene) and non-transgenic soybean plants through proteomics and metabolomics. For proteomics…”
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Identification of novel Zika virus NS3 protease inhibitors with different inhibition modes by integrative experimental and computational approaches by Andrade, Milene Aparecida, Mottin, Melina, Sousa, Bruna K.de P., Barbosa, João Alexandre Ribeiro Gonçalves, dos Santos Azevedo, Clênia, Lasse Silva, Camila, Gonçalves de Andrade, Marina, Motta, Flávia Nader, Maulay-Bailly, Christine, Amand, Séverine, Santana, Jaime Martins de, Horta Andrade, Carolina, Grellier, Philippe, Bastos, Izabela M.D.

“…Zika virus (ZIKV) infection is associated with severe neurological disorders and congenital malformation. Despite efforts to eradicate the disease, there is…”
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