Search Results - "Brun, Johan G"
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High Fidelity Between Saliva Proteomics and the Biologic State of Salivary Glands Defines Biomarker Signatures for Primary Sjögren's Syndrome
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2015)“…Objective Dependence on invasive procedures for classification of patients with Sjögren's syndrome (SS) hampers timely diagnosis and suitable patient followup…”
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Subgingival microbiome of rheumatoid arthritis patients in relation to their disease status and periodontal health
Published in PloS one (19-09-2018)“…Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases that share common risk factors. However, the bidirectional relationship between…”
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EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjogren's syndrome
Published in Annals of the rheumatic diseases (01-06-2011)“…To develop a score for assessment of patients' symptoms in primary Sjögren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI). Dryness, pain,…”
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Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren's syndrome
Published in Arthritis research & therapy (07-05-2022)“…Interleukin-2 (IL-2) and the high-affinity IL-2 receptor (IL-2R) are essential for the survival of regulatory T cells (Tregs) which are the main players in…”
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Inflammatory Stratification in Primary Sjögren's Syndrome Reveals Novel Immune Cell Alterations in Patients' Minor Salivary Glands
Published in Frontiers in immunology (12-07-2021)“…There is a critical need to deconvolute the heterogeneity displayed by the minor salivary glands of primary Sjögren's syndrome (pSS) patients. This is…”
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Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation
Published in Scientific reports (05-03-2021)“…Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases with several pathogenic pathways in common. Evidence supports an association…”
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Aberrant signaling of immune cells in Sjögren’s syndrome patient subgroups upon interferon stimulation
Published in Frontiers in immunology (22-08-2022)“…Background Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, characterized by mononuclear cell infiltrates in the salivary and lacrimal…”
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Single Cell Based Phosphorylation Profiling Identifies Alterations in Toll-Like Receptor 7 and 9 Signaling in Patients With Primary Sjögren's Syndrome
Published in Frontiers in immunology (21-02-2019)“…Primary Sjögren's syndrome (pSS) is associated with polymorphisms and mRNA expression profiles that are indicative of an exaggerated innate and type I IFN…”
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Risk of Non‐Hodgkin's Lymphoma in Primary Sjögren's Syndrome: A Population‐Based Study
Published in Arthritis care & research (2010) (01-05-2013)“…Objective Primary Sjögren's syndrome (SS) is associated with an increased risk of non‐Hodgkin's lymphoma (NHL), but the reported prevalence and risk vary…”
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257 ankle arthroplasties performed in Norway between 1994 and 2005
Published in Acta orthopaedica (01-01-2007)“…There have been few reports on the long-term outcome of ankle replacements. The Norwegian Arthroplasty Register has been registering ankle replacements since…”
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Expression of Toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome
Published in PloS one (19-03-2015)“…Sjögren's syndrome (SS) is a rheumatic autoimmune disease characterized by inflammation of exocrine glands. As autoantibodies are present in a majority of…”
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Impact of lean mass and fat mass on bone mineral density: The Hordaland Health Study
Published in Maturitas (20-02-2008)“…Abstract Objectives To examine the relationship between soft tissue composition and bone mineral density (BMD) of the hip and whether these relationships…”
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Prevalence, disease manifestations, and treatment of psoriatic arthritis in Western Norway
Published in Journal of rheumatology (01-10-2005)“…OBJECTIVE: To estimate the prevalence of psoriatic arthritis (PsA) in a geographically defined population, and to characterize the clinical manifestations and…”
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S100 proteins calprotectin and S100A12 are related to radiographic changes rather than disease activity in psoriatic arthritis with low disease activity
Published in Journal of rheumatology (01-10-2007)“…OBJECTIVE: To investigate serum levels of calprotectin (S100A8/S100A9) and S100A12 as markers of disease activity or distinct clinical or radiographic features…”
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Implications of long-term medication of oral steroids and antimalarial drugs in primary Sjögren's syndrome
Published in International immunopharmacology (01-12-2011)“…Immunomodulating drugs are commonly used in treating patients with autoimmune diseases but with very different outcomes. We aimed to investigate differences in…”
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Aberrant cell signalling in PBMCs upon IFN‐α stimulation in primary Sjögren's syndrome patients associates with type I interferon signature
Published in European journal of immunology (01-07-2018)“…Primary Sjögren's syndrome (pSS) is a complex systemic autoimmune disease with heterogeneous disease manifestations. Genetic predisposition, hormonal and…”
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Immunoglobulin G and A antibody responses to Bacteroides forsythus and Prevotella intermedia in sera and synovial fluids of arthritis patients
Published in Clinical and diagnostic laboratory immunology (01-11-2003)“…The objective of the present study was to investigate immunoglobulin G (IgG) and IgA antibody immune responses to Porphyromonas gingivalis, Prevotella…”
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Validation of EULAR primary Sjögren's syndrome disease activity (ESSDAI) and patient indexes (ESSPRI)
Published in Annals of the rheumatic diseases (01-05-2015)“…To validate the two recently developed disease activity indexes for assessment of primary Sjögren's syndrome (SS): the European League Against Rheumatism…”
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Serum Markers in Rheumatoid Arthritis: A Longitudinal Study of Patients Undergoing Infliximab Treatment
Published in International Journal of Rheumatology (01-01-2015)“…Objective. The aim of this study was to investigate the clinical effect and serum markers in a cohort of rheumatoid arthritis patients with moderate to high…”
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Marine ω-3, vitamin D levels, disease outcome and periodontal status in rheumatoid arthritis outpatients
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-11-2018)“…•Periodontitis was most prevalent in patients with rheumatoid arthritis (RA) who were seropositive for rheumatoid factor and/or anticitrullinated protein…”
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