Search Results - "Brun, Caroline E."

The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration by Hernández-Hernández, J. Manuel, García-González, Estela G., Brun, Caroline E., Rudnicki, Michael A.

“…The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are members of the basic helix-loop-helix family of transcription factors that control the…”
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EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions by Wang, Yu Xin, Feige, Peter, Brun, Caroline E., Hekmatnejad, Bahareh, Dumont, Nicolas A., Renaud, Jean-Marc, Faulkes, Sharlene, Guindon, Daniel E., Rudnicki, Michael A.

“…Loss of dystrophin expression in Duchenne muscular dystrophy (DMD) causes progressive degeneration of skeletal muscle, which is exacerbated by reduced…”
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The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment by Chang, Natasha C., Sincennes, Marie-Claude, Chevalier, Fabien P., Brun, Caroline E., Lacaria, Melanie, Segalés, Jessica, Muñoz-Cánoves, Pura, Ming, Hong, Rudnicki, Michael A.

“…Asymmetrically dividing muscle stem cells in skeletal muscle give rise to committed cells, where the myogenic determination factor Myf5 is transcriptionally…”
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GDF11 and the Mythical Fountain of Youth by Brun, Caroline E., Rudnicki, Michael A.

“…Identifying candidates that rejuvenate aged muscle stem cells is an important strategy toward developing therapies to treat age-related diseases. In this…”
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Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice by Sincennes, Marie-Claude, Brun, Caroline E., Lin, Alexander Y. T., Rosembert, Tabitha, Datzkiw, David, Saber, John, Ming, Hong, Kawabe, Yoh-ichi, Rudnicki, Michael A.

“…Muscle stem cell function has been suggested to be regulated by Acetyl-CoA and NAD+ availability, but the mechanisms remain unclear. Here we report the…”
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GLI3 regulates muscle stem cell entry into GAlert and self-renewal by Brun, Caroline E., Sincennes, Marie-Claude, Lin, Alexander Y. T., Hall, Derek, Jarassier, William, Feige, Peter, Le Grand, Fabien, Rudnicki, Michael A.

“…Satellite cells are required for the growth, maintenance, and regeneration of skeletal muscle. Quiescent satellite cells possess a primary cilium, a structure…”
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MLL1 is required for PAX7 expression and satellite cell self-renewal in mice by Addicks, Gregory C., Brun, Caroline E., Sincennes, Marie-Claude, Saber, John, Porter, Christopher J., Francis Stewart, A., Ernst, Patricia, Rudnicki, Michael A.

“…PAX7 is a paired-homeobox transcription factor that specifies the myogenic identity of muscle stem cells and acts as a nodal factor by stimulating…”
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Concise Review: Epigenetic Regulation of Myogenesis in Health and Disease by Sincennes, Marie-Claude, Brun, Caroline E., Rudnicki, Michael A.

“…Skeletal muscle regeneration is initiated by satellite cells, a population of adult stem cells that reside in the muscle tissue. The ability of satellite cells…”
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Mouse WIF1 Is Only Modified with O -Fucose in Its EGF-like Domain III Despite Two Evolutionarily Conserved Consensus Sites by Pennarubia, Florian, Pinault, Emilie, Al Jaam, Bilal, Brun, Caroline E, Maftah, Abderrahman, Germot, Agnès, Legardinier, Sébastien

“…The Wnt Inhibitory Factor 1 (Wif1), known to inhibit Wnt signaling pathways, is composed of a WIF domain and five EGF-like domains (EGF-LDs) involved in…”
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Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division by Dumont, Nicolas A, Wang, Yu Xin, von Maltzahn, Julia, Pasut, Alessandra, Bentzinger, C Florian, Brun, Caroline E, Rudnicki, Michael A

“…Dystrophin is expressed in muscle stem cells, in which it regulates their cell division and proper repopulation. Dystrophin is expressed in differentiated…”
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Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease by Feige, Peter, Brun, Caroline E., Ritso, Morten, Rudnicki, Michael A.

“…Muscle stem cells, or satellite cells, are required for skeletal muscle maintenance, growth, and repair. Following satellite cell activation, several factors…”
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Single EDL Myofiber Isolation for Analyses of Quiescent and Activated Muscle Stem Cells by Brun, Caroline E, Wang, Yu Xin, Rudnicki, Michael A

“…Adult satellite cells are quiescent, but are poised for activation in response to exercise, injury, or disease allowing adult muscle growth or repair. Once…”
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GLI3 processing in the primary cilia of muscle stem cells controls their quiescence state by Sincennes, Marie-Claude, Brun, Caroline E

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GLI3 regulates muscle stem cell entry into G Alert and self-renewal by Brun, Caroline E, Sincennes, Marie-Claude, Lin, Alexander Y T, Hall, Derek, Jarassier, William, Feige, Peter, Le Grand, Fabien, Rudnicki, Michael A

“…Satellite cells are required for the growth, maintenance, and regeneration of skeletal muscle. Quiescent satellite cells possess a primary cilium, a structure…”
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Cell-autonomous defects in satellite cells impair muscle regeneration in Duchenne muscular dystrophy by Brun, Caroline E, Dumont, Nicolas A

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