Search Results - "Brun, Ann C.M"

Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects by Magnusson, Mattias, Brun, Ann C.M, Lawrence, H. Jeffrey, Karlsson, Stefan

“…Objective Members of the hox family of homeodomain-containing transcription factors, including hoxa9, hoxb3, and hoxb4 play an important role in the regulation…”
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Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond–Blackfan anemia improves following RPS19 gene transfer by Hamaguchi, Isao, Flygare, Johan, Nishiura, Hiroshi, Brun, Ann C.M, Ooka, Andreas, Kiefer, Thomas, Ma, Zhi, Dahl, Niklas, Richter, Johan, Karlsson, Stefan

“…Diamond–Blackfan anemia (DBA) is a congenital bone marrow failure syndrome characterized by a specific deficiency in erythroid progenitors. Since some patients…”
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HOXB4‐Induced Self‐Renewal of Hematopoietic Stem Cells Is Significantly Enhanced by p21 Deficiency by Miyake, Noriko, Brun, Ann C.M., Magnusson, Mattias, Miyake, Koichi, Scadden, David T., Karlsson, Stefan

“…Enforced expression of the HOXB4 transcription factor and downregulation of p21Cip1/Waf (p21) can each independently increase proliferation of murine…”
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Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: Applications and prospects by Järås, Marcus, Brun, Ann C.M, Karlsson, Stefan, Fan, Xiaolong

“…The proliferation and differentiation of primitive hematopoietic cells is tightly controlled by a number of signaling pathways. Transient blockage or…”
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Enforced adenoviral vector-mediated expression of HOXB4 in human umbilical cord blood cd34+ cells promotes myeloid differentiation but not proliferation by Brun, Ann C.M, Fan, Xiaolong, Björnsson, Jon Mar, Humphries, R.Keith, Karlsson, Stefan

“…Retroviral overexpression of the transcription factor HOXB4 results in a rapid increase in proliferation of murine hematopoietic stem cells both in vivo and in…”
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HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development by Magnusson, Mattias, Brun, Ann C.M., Miyake, Noriko, Larsson, Jonas, Ehinger, Mats, Bjornsson, Jon Mar, Wutz, Anton, Sigvardsson, Mikael, Karlsson, Stefan

“…The Homeobox (Hox) transcription factors are important regulators of normal and malignant hematopoiesis because they control proliferation, differentiation,…”
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Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells by Brun, Ann C.M., Björnsson, Jon Mar, Magnusson, Mattias, Larsson, Nina, Leveén, Per, Ehinger, Mats, Nilsson, Eva, Karlsson, Stefan

“…Enforced expression of Hoxb4 dramatically increases the regeneration of murine hematopoietic stem cells (HSCs) after transplantation and enhances the…”
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Hematopoietic stem cell–targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice by Johansson, Maria K., de Vries, Teun J., Schoenmaker, Ton, Ehinger, Mats, Brun, Ann C.M., Fasth, Anders, Karlsson, Stefan, Everts, Vincent, Richter, Johan

“…Infantile malignant osteopetrosis (IMO) is a fatal disease caused by lack of functional osteoclasts, and the only available treatment is hematopoietic stem…”
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Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient in Hoxb3 and Hoxb4 by Björnsson, Jon Mar, Larsson, Nina, Brun, Ann C M, Magnusson, Mattias, Andersson, Elisabet, Lundström, Patrik, Larsson, Jonas, Repetowska, Ewa, Ehinger, Mats, Humphries, R Keith, Karlsson, Stefan

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hematopoietic Stem Cell Expansion by HOXB4 Is Greatly Enhanced in p21 Deficient Stem Cells by Miyake, Noriko, Brun, Ann C.M., Magnusson, Mattias, Scadden, David T., Karlsson, Stefan

“…Hox transcription factors have emerged as important regulators of hematopoiesis. In particular, enforced expression of HOXB4 is a potent stimulus for murine…”
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HOXA10 Affects the Fate of Hematopoietic Progenitors and Stem Cells in a Concentration Dependent Manner by Brun, Ann C.M., Magnusson, Mattias, Miyake, Noriko, Nilsson, Eva, Björnsson, Jon Mar, Karlsson, Stefan

“…Several studies have demonstrated that homeobox (Hox) genes are involved in the regulation of hematopoietic stem cells (HSC), and overexpression with…”
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High Levels of HoxA10 Severely Impair Erythoid Development In Vivo and Cause Lethal Anemia by Magnusson, Mattias, Brun, Ann C.M., Miyake, Noriko, Ehinger, Mats, Nilsson, Eva, Björnsson, Jon Mar, Karlsson, Stefan

“…Several Homeobox transcription factors (Hox) have been shown to be highly involved in the complex regulation of hematopoiesis, controlling proliferation,…”
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Overexpression of Gibbon Ape Leukemia Virus (GALV) Receptor (GLVR1) on Human CD34+ Cells Increases Gene Transfer Mediated by GALV Pseudotyped Vectors by Relander, Thomas, Brun, Ann C.M., Olsson, Karin, Pedersen, Lene, Richter, Johan

“…Retroviral transduction of CD34+ cells on Retronectin using gibbon ape leukemia virus (GALV) pseudotyped vectors is inhibited by high concentrations of vector…”
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