Search Results - "Brumpton, Ben M."
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Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study
Published in PLoS medicine (16-11-2020)“…In observational studies of the general population, higher body mass index (BMI) has been associated with increased incidence of and mortality from bloodstream…”
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2
The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
Published in Nature communications (11-08-2022)“…Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of…”
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3
Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema
Published in PloS one (27-05-2021)“…Previous studies of associations of forced expiratory lung volume in one second (FEV 1 ) with peak oxygen uptake (VO 2peak ) in chronic obstructive pulmonary…”
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4
Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study
Published in European journal of epidemiology (01-11-2021)“…The association between bone mineral density (BMD) and cardiovascular disease (CVD) is not fully understood. We evaluated BMD as a risk factor for…”
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5
Polygenic Interactions With Environmental Exposures in Blood Pressure Regulation: The HUNT Study
Published in Journal of the American Heart Association (01-10-2024)“…The essential hypertension phenotype results from an interplay between genetic and environmental factors. The influence of lifestyle exposures such as excess…”
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6
The association between normal lung function and peak oxygen uptake in patients with exercise intolerance and coronary artery disease
Published in PloS one (04-05-2020)“…In coronary artery disease (CAD), exercise intolerance with reduced oxygen uptake at peak exercise (VO2peak) is assumed to primarily reflect cardiovascular…”
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7
Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study
Published in The European respiratory journal (01-06-2018)“…We aimed to investigate potential causal associations between serum 25-hydroxyvitamin D (25(OH)D) levels and incidence of lung cancer overall and histologic…”
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The association between dynamic lung volume and peak oxygen uptake in a healthy general population: the HUNT study
Published in BMC pulmonary medicine (06-01-2019)“…Although dynamic lung volume is not considered a limiting factor of peak oxygen uptake (VO ) in healthy subjects, an association between forced expiratory lung…”
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9
Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT
Published in Communications biology (16-06-2022)“…Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here,…”
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10
Cohort Profile Update: The HUNT Study, Norway
Published in International journal of epidemiology (08-02-2023)“…In the HUNT Study, all residents aged ≥20 years in the Nord-Trøndelag region, Norway, have been invited to repeated surveys since 1984-86. The study data may…”
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11
Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses
Published in Hypertension (Dallas, Tex. 1979) (01-06-2021)“…Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This…”
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12
Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease
Published in European journal of preventive cardiology (20-09-2024)“…Resting heart rate (RHR) is associated with cardiovascular disease (CVD) and mortality. This study aimed to identify genetic loci associated with RHR, develop…”
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13
Genome-Wide Association Study Identifies New Genetic Determinants of Cardiorespiratory Fitness: The Trøndelag Health Study
Published in Medicine and science in sports and exercise (01-09-2022)“…Low cardiorespiratory fitness (CRF) is a major risk factor for cardiovascular disease (CVD) and a stronger predictor of CVD morbidity and mortality than…”
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14
Polygenic prediction of preeclampsia and gestational hypertension
Published in Nature medicine (01-06-2023)“…Preeclampsia and gestational hypertension are common pregnancy complications associated with adverse maternal and child outcomes. Current tools for prediction,…”
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15
A genome-wide association study of susceptibility to upper urinary tract infections
Published in The Journal of infectious diseases (07-05-2024)“…Our goal was to identify genetic and modifiable risk factors for upper urinary tract infections (UTIs). We used data from UK Biobank, The Trøndelag Health…”
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16
Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study
Published in Europace (London, England) (05-10-2023)“…Abstract Aims A low resting heart rate (RHR) implies a more efficient heart function and a lower risk of cardiovascular disease. However, observational studies…”
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17
Investigating obesity‐related risk factors for childhood asthma
Published in Pediatric allergy and immunology (01-01-2022)“…Background We tested the hypothesis that multiple obesity‐related risk factors (obesity, physical activity, cardiopulmonary physical fitness, sleep‐disorder…”
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18
Is high vitamin B12 status a cause of lung cancer?
Published in International journal of cancer (15-09-2019)“…Vitamin B supplementation can have side effects for human health, including cancer risk. We aimed to elucidate the role of vitamin B12 in lung cancer etiology…”
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19
Sex- and age-specific genetic analysis of chronic back pain
Published in Pain (Amsterdam) (01-04-2021)“…Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity, and poorer response to treatment…”
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20
Polygenic risk scores associate with blood pressure traits across the lifespan
Published in European journal of preventive cardiology (18-04-2024)“…Hypertension is a major modifiable cause of morbidity and mortality that affects over 1 billion people worldwide. Blood pressure (BP) traits have a strong…”
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