Search Results - "Brummet, Mary E."

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis by Kiwamoto, Takumi, MD, PhD, Katoh, Toshihiko, PhD, Evans, Christopher M., PhD, Janssen, William J., MD, Brummet, Mary E., MS, Hudson, Sherry A., MSB, Zhu, Zhou, MD, PhD, Tiemeyer, Michael, PhD, Bochner, Bruce S., MD

“…Background Sialic acid–binding, immunoglobulin-like lectin (Siglec) F is a glycan-binding protein selectively expressed on mouse eosinophils. Its engagement…”
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Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation by Kiwamoto, Takumi, MD, PhD, Brummet, Mary E., MS, Wu, Fan, Motari, Mary G, Smith, David F., PhD, Schnaar, Ronald L., PhD, Zhu, Zhou, MD, PhD, Bochner, Bruce S., MD

“…Background Sialic acid–binding immunoglobulin-like lectin (Siglec)-F is a proapoptotic receptor on mouse eosinophils, but little is known about its natural…”
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Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency by Kumagai, Tadahiro, Kiwamoto, Takumi, Brummet, Mary E, Wu, Fan, Aoki, Kazuhiro, Zhu, Zhou, Bochner, Bruce S, Tiemeyer, Michael

“…Abstract Siglec-F is a pro-apoptotic receptor on mouse eosinophils that recognizes 6′-sulfated sialyl Lewis X and 6′-sulfated sialyl N-acetyl-lactosamine as…”
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Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs by Guo, Jin P, Brummet, Mary E, Myers, Allen C, Na, Ho Jeong, Rowland, Elizabeth, Schnaar, Ronald L, Zheng, Tao, Zhu, Zhou, Bochner, Bruce S

“…Sialic acid-binding immunoglobulin-like lectin (Siglec)-F, an inhibitory receptor on mouse eosinophils, preferentially recognizes the glycan ligand 6'-sulfated…”
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The Airway Mucins Muc5b and Muc4 Are Endogenous Ligands For Siglec-F and Induce Mouse Eosinophil Death by Kiwamoto, Takumi, MD, PhD, Katoh, Toshihiko, PhD, Evans, Christopher, PhD, Brummet, Mary E., MS, Hudson, Sherry, MS, Zhu, Zhou, MD, PhD, Tiemeyer, Michael, PhD, Bochner, Bruce S., MD, FAAAAI

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Functional Analysis of the Chemokine Receptor CCR3 on Airway Epithelial Cells by Beck, Lisa A, Tancowny, Brian, Brummet, Mary E, Asaki, S. Yukiko, Curry, Stephanie L, Penno, Margaret B, Foster, Martyn, Bahl, Ash, Stellato, Cristiana

“…The function of chemokine receptors on structural cells is only partially known. We previously reported the expression of a functional CCR3 receptor on airway…”
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Cutting Edge: Expression of the C-C Chemokine Receptor CCR3 in Human Airway Epithelial Cells by Stellato, Cristiana, Brummet, Mary E, Plitt, James R, Shahabuddin, Syed, Baroody, Fuad M, Liu, Mark C, Ponath, Paul D, Beck, Lisa A

“…Chemokine-induced eosinophil chemotaxis is mediated primarily through the C-C chemokine receptor, CCR3. We have now detected CCR3 immunoreactivity on…”
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Activation of Human Leukocytes Reduces Surface P-Selectin Glycoprotein Ligand-1 (PSGL-1, CD162) and Adhesion to P-Selectin In Vitro by Davenpeck, Kelly L, Brummet, Mary E, Hudson, Sherry A, Mayer, Ruth J, Bochner, Bruce S

“…P-selectin glycoprotein ligand-1 (PSGL-1), the primary ligand for P-selectin, is constitutively expressed on the surface of circulating leukocytes. The…”
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Mice with Attenuated Expression of the α2,3 Sialyltransferase ST3gal-III (St3gal3) Display Enhanced Allergic Eosinophilic Airway Inflammation by Kiwamoto, Takumi, MD, PhD, Brummet, Mary E, Motari, Mary, Schnaar, Ronald, PhD, Zhu, Zhou, MD, PhD, Bochner, Bruce S., MD, FAAAAI

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Polymorphisms in the novel gene acyloxyacyl hydroxylase ( AOAH) are associated with asthma and associated phenotypes by Barnes, Kathleen C., Grant, Audrey, Gao, Peisong, Baltadjieva, Daniela, Berg, Tiina, Chi, Peter, Zhang, Shu, Zambelli-Weiner, April, Ehrlich, Eva, Zardkoohi, Omeed, Brummet, Mary E., Stockton, Maria, Watkins, Tonya, Gao, Li, Gittens, Marquita, Wills-Karp, Marsha, Cheadle, Christopher, Beck, Lisa A., Beaty, Terri H., Becker, Kevin G., Garcia, Joe G.N., Mathias, Rasika A.

“…The gene encoding acyloxyacyl hydroxylase (AOAH), an enzyme that hydrolyzes secondary fatty acyl chains of LPS, is localized on chromosome 7p14-p12, where…”
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Loss of Oxygen Transport Potency As a Function of RBC Storage Duration by Rogers, Stephen C, Enjati, Sarah, Brummet, Mary E, Balovich, Taylor, Safari, Zohreh, Doctor, Allan

“…BACKROUND: Red blood cell (RBC) oxygen (O 2) capture/release is regulated via homeostatic modulation of hemoglobin oxygen (Hb-O 2) affinity in a manner that…”
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RBC eNOS Transduces Regional O2 Gradients to Orchestrate RBC O2 Delivery Phenotype during Circulatory Transit by Safari, Zohreh, Rogers, Stephen C, Brummet, Mary E, Wang, Qihong, Okhuevbie, Joy, Issaian, Aaron, Dzieciatkowska, Monika, Gamboni, Fabia, Held, Jason, D'Alessandro, Angelo, Cortese Krott, Miriam, Doctor, Allan

“…BACKGROUND: The role of endogenous endothelial NO synthase (eNOS) in mature RBCs is poorly understood. We have previously demonstrated functionally…”
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Expression and function of P-selectin glycoprotein ligand 1 (CD162) on human basophils by Taylor, Marcia L., Brummet, Mary E., Hudson, Sherry A., Miura, Katsu, Bochner, Bruce S.

“…Background: The endothelial cell adhesion molecule P-selectin may contribute to selective leukocyte migration in allergic diseases by binding to its ligand,…”
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Mice deficient in the St3gal3 gene product alpha 2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation by Kiwamoto, Takumi, Brummet, Mary, Wu, Fan, Motari, Mary, Smith, David, Schnaar, Ronald, Zhu, Zhou, Bochner, Bruce

“…Background: Sialic acid-binding immunoglobulin-like lectin (Siglec)-F is a proapoptotic receptor on mouse eosinophils, but little is known about its natural…”
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Analysis of the three-dimensional antigenic structure of giant ragweed allergen, Amb t 5 by Rafnar, Thorunn, Brummet, Mary E, Bassolino-Klimas, Donna, Metzler, William J, Marsh, David G

“…The ragweed allergens Amb t 5 and Amb a 5 are among the smallest inhaled protein allergens known, containing a single, immunodominant T-cell epitope. In this…”
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Stimulation of the high-affinity IgE receptor results in the tyrosine phosphorylation of a 60 kD protein which is associated with the protein-tyrosine kinase, Csk by Rafnar, Thorunn, Peebles, R.Stokes, Brummet, Mary E, Čatipović, Branimir, Imani, Farhad, MacGlashan, Donald W, Marsh, David G

“…The protein tyrosine kinase Csk downregulates the activity of the Src family of kinases and has a negative effect on signal transduction through several Src…”
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Csk Is Constitutively Associated with a 60-kDa Tyrosine-phosphorylated Protein in Human T Cells (∗) by Catipovic, Branimir, Schneck, Jonathan P., Brummet, Mary E., Marsh, David G., Rafnar, Thorunn

“…The protein-tyrosine kinase Csk is one of the main down-regulators of the Src family of kinases. Csk may be involved in the down-regulation of T cell receptor…”
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Mice deficient in theSt3gal3gene product [alpha]2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation by Kiwamoto, Takumi, Brummet, Mary E, Wu, Fan, Motari, Mary G, Smith, David F, Schnaar, Ronald L, Zhu, Zhou, Bochner, Bruce S

“…Background Sialic acid-binding immunoglobulin-like lectin (Siglec)-F is a proapoptotic receptor on mouse eosinophils, but little is known about its natural…”
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Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes by Lee, S C, Brummet, M E, Shahabuddin, S, Woodworth, T G, Georas, S N, Leiferman, K M, Gilman, S C, Stellato, C, Gladue, R P, Schleimer, R P, Beck, L A

“…Macrophage inflammatory protein (MIP-1 alpha), a member of the CC chemokine subfamily, has been shown to attract T cells and monocytes in vitro and to be…”
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Characterization of Vaccine Site and Cellular Infiltrate in Subjects with Chronic Myeloid Leukemia (CML) Receiving K562/GM-CSF Vaccination in Combination with Imatinib Mesylate with or without Topical Imiquimod by Chia, Christina Y., Smith, B. Douglas, Kasamon, Yvette, Miller, Carole B., Brummet, Mary E., Bankova, Lora, Kowalski, Jeanne, Biedrzycki, Barbara, Hege, Kristen, Beck, Lisa A., Levitsky, Hyam

“…Increased understanding of the local injection site infiltrate in response to tumor vaccines may facilitate more effective anti-cancer vaccination strategies…”
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