Search Results - "Brummer, T"

MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation by Stickel, N, Hanke, K, Marschner, D, Prinz, G, Köhler, M, Melchinger, W, Pfeifer, D, Schmitt-Graeff, A, Brummer, T, Heine, A, Brossart, P, Wolf, D, von Bubnoff, N, Finke, J, Duyster, J, Ferrara, J, Salzer, U, Zeiser, R

“…Acute Graft-versus-host disease (GVHD) is a major immunological complication after allogeneic hematopoietic cell transplantation and a better understanding of…”
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Alien and native plant richness and abundance respond to different environmental drivers across multiple gravel floodplain ecosystems by Brummer, T. J., Byrom, A. E., Sullivan, J. J., Hulme, P. E.

“…AIM: To assess whether native and alien plant cover and richness respond similarly to flow regime, propagule pressure, climate and floodplain characteristics…”
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Cooperation of BRAF(F595L) and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling by Kordes, M, Röring, M, Heining, C, Braun, S, Hutter, B, Richter, D, Geörg, C, Scholl, C, Gröschel, S, Roth, W, Rosenwald, A, Geissinger, E, von Kalle, C, Jäger, D, Brors, B, Weichert, W, Grüllich, C, Glimm, H, Brummer, T, Fröhling, S

“…Activating BRAF mutations, in particular V600E/K, drive many cancers and are considered mutually exclusive with mutant RAS, whereas inactivating BRAF mutations…”
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Authors' reply: There must be more to surgical wound infection prevention than antibiotic prophylaxis alone by Brummer, T, Härkki, P

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Stress urinary incontinence after hysterectomy: a 10-year national follow-up study by Tulokas, Sari, Mentula, M., Härkki, P., Brummer, T., Jalkanen, J., Kuittinen, T., Mäkinen, J., Sjöberg, J., Tomas, E., Rahkola-Soisalo, P.

“…Purpose Hysterectomy has been associated with increased risk for developing stress urinary incontinence (SUI) and having a SUI operation. We examined the…”
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Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors by Wöhrle, F U, Halbach, S, Aumann, K, Schwemmers, S, Braun, S, Auberger, P, Schramek, D, Penninger, J M, Laßmann, S, Werner, M, Waller, C F, Pahl, H L, Zeiser, R, Daly, R J, Brummer, T

“…Grb2-associated binder 2 (Gab2) serves as a critical amplifier in the signaling network of Bcr-Abl, the driver of chronic myeloid leukemia (CML). Despite the…”
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Pharmaceutical thrombosis prophylaxis, bleeding complications and thromboembolism in a national cohort of hysterectomy for benign disease by Brummer, T.H.I., Heikkinen, A., Jalkanen, J., Fraser, J., Mäkinen, J., Tomás, E., Seppälä, T., Sjöberg, J., Härkki, P.

“…BACKGROUND Pharmaceutical thrombosis prophylaxis (PTP) with low-molecular-weight heparin (LMWH) is highly effective in preventing venous thromboembolic events…”
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Functional characterization of cancer-associated Gab1 mutations by Ortiz-Padilla, C, Gallego-Ortega, D, Browne, B C, Hochgräfe, F, Caldon, C E, Lyons, R J, Croucher, D R, Rickwood, D, Ormandy, C J, Brummer, T, Daly, R J

“…Grb2-associated binder 1 (Gab1) is a docking protein that transduces signals from a variety of tyrosine kinases, including Met and the epidermal growth factor…”
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Gab2 is essential for Bcr-Abl-mediated leukemic transformation and hydronephrosis in a chronic myeloid leukemia mouse model by Halbach, S, Köhler, M, Uhl, F M, Huber, J, Zeiser, R, Koschmieder, S, Aumann, K, Brummer, T

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Antibiotic prophylaxis for hysterectomy, a prospective cohort study: cefuroxime, metronidazole, or both? by Brummer, THI, Heikkinen, A‐M, Jalkanen, J, Fraser, J, Mäkinen, J, Tomás, E, Seppälä, T, Sjöberg, J, Härkki, P

“…Objective To evaluate cefuroxime and metronidazole antibiotic prophylaxis. Design Observational nonrandomised 1‐year prospective cohort study. Setting…”
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196: System-wide characterization of dynamics of cytosolic macromolecular protein complexes during oncogene-induced cell transformation by Diedrich, B, Rigbolt, K.G, Bestmann, S, Brummer, T, Dengjel, J

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A Quantitative Framework to Derive Robust Characterization of Hydrological Gradients by Brummer, T. J., Byrom, A. E., Sullivan, J. J., Hulme, P. E.

“…If ecological management of river ecosystems is to keep pace with increasing pressure to , divert and dam, we must develop general flow–ecology relationships…”
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Stability structures tropical woody plant diversity more than seasonality: Insights into the ecology of high legume-succulent-plant biodiversity by Oliveira-Filho, A.T., Cardoso, D., Schrire, B.D., Lewis, G.P., Pennington, R.T., Brummer, T.J., Rotella, J., Lavin, M.

“…Phylogenies of legume taxa are ecologically structured along a tropical seasonality gradient, which suggests phylogenetic niche conservatism. This seasonality…”
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Functional analysis of the regulatory requirements of B-Raf and the B-Raf oncoprotein by Brummer, T, Martin, P, Herzog, S, Misawa, Y, Daly, R J, Reth, M

“…The BRAF(V600E) mutation is found in approximately 6% of human cancers and mimics the phosphorylation of the kinase domain activation segment. In wild-type…”
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The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity by Holeiter, G, Bischoff, A, Braun, A C, Huck, B, Erlmann, P, Schmid, S, Herr, R, Brummer, T, Olayioye, M A

“…Epithelial cell–cell contacts are mediated by E-cadherin interactions, which are regulated by the balanced local activity of Rho GTPases. Despite the known…”
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Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis by Bennett, H L, Brummer, T, Jeanes, A, Yap, A S, Daly, R J

“…The Gab2 docking protein is a target of several oncogenic protein tyrosine kinases and potentiates activation of the Ras/extracellular signal regulated kinase…”
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Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling by Brummer, Tilman, Shaw, Peter E., Reth, Michael, Misawa, Yukiko

“…Engagement of the B‐cell antigen receptor (BCR) leads to activation of the Raf–MEK–ERK pathway and Raf kinases play an important role in the modulation of ERK…”
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Depletion of STAT5 blocks TEL–SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice by Sprissler, C, Belenki, D, Maurer, H, Aumann, K, Pfeifer, D, Klein, C, Müller, T A, Kissel, S, Hülsdünker, J, Alexandrovski, J, Brummer, T, Jumaa, H, Duyster, J, Dierks, C

“…The spleen tyrosine kinase (SYK) was identified as an oncogenic driver in a broad spectrum of hematologic malignancies. The in vivo comparison of three SYK…”
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Compact all-optical precision-tunable narrowband hard Compton X-ray source by Brümmer, T., Bohlen, S., Grüner, F., Osterhoff, J., Põder, K.

“…Readily available bright X-ray beams with narrow bandwidth and tunable energy promise to unlock novel developments in a wide range of applications. Among…”
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National learning curve for laparoscopic hysterectomy and trends in hysterectomy in Finland 2000–2005 by Brummer, Tea H.I., Seppälä, Tomi T., Härkki, Päivi S.M.

“…BACKGROUND Complications of laparoscopic hysterectomy (LH) have been evaluated with particular focus on quantities of urinary tract injuries. An earlier survey…”
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