Search Results - "Brumme, Z"

Operationalizing the One Health approach: the global governance challenges by Lee, Kelley, Brumme, Zabrina L.

“…While there has been wide-ranging commitment to the One Health approach, its operationalisation has so far proven challenging. One Health calls upon the human,…”
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PP 3.6 – 00122 Heterogeneous associations between HIV genomic integrity and proviral longevity during long-term ART by Z. Brumme, N. Kinloch, A. Shahid, W. Dong, D. Kirkby, B.R. Jones, C. Beelen, D. MacMillan, T.M. Mota, H. Sudderuddin, E. Barad, M. Harris, C.J. Brumme, R. Brad Jones, M.A. Brockman, J.B. Joy

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Differential escape patterns within the dominant HLA-B57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints by Payne, R P, Branch, S, Kløverpris, H, Matthews, P C, Koofhethile, C K, Strong, T, Adland, E, Leitman, E, Frater, J, Ndung'u, T, Hunter, E, Haubrich, R, Mothe, B, Edwards, A, Riddell, L, Chen, F, Harrigan, P R, Brumme, Z L, Mallal, S, John, M, Jooste, J P, Shapiro, R, Deeks, S G, Walker, B D, Brander, C, Landis, C, Carlson, J M, Prado, J G, Goulder, P J R

“…HLA-B*57:01 and HLA-B*57:03, the most prevalent HLA-B*57 subtypes in Caucasian and African populations, respectively, are the HLA alleles most protective…”
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HIV post-treatment control despite plasma viral evolution and dual infection by J. Li, B. Etemad, G. Namazi, Y. Wen, N. Jilg, E. Esmaeilzadeh, X. Zhang, R. Sharaf, Z. Brumme, M. Kearney

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Persistent HIV reservoir suppression by (-)-hopeaphenol, a plant-derived stilbenoid by I. Tietjen, Z. Haq, M. Naidu, J. Rivera-Ortiz, Y. Cai, K. Beattie, T. Rali, Z. Brumme, L. Montaner, R. Davis

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Human Immunodeficiency Virus Type 1 Protease Cleavage Site Mutations Associated with Protease Inhibitor Cross-Resistance Selected by Indinavir, Ritonavir, and/or Saquinavir by Côté, Hélène C. F., Brumme, Zabrina L., Harrigan, P. Richard

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Discovery and mechanistic study of novel suppressors of post-integrated HIV expression from African natural products by C. Schonhofer, K. Andrae-Marobela, J. Yi, A. Cochrane, A. Pagliuzza, B. Abegaz, R. Davis, N. Chomont, Z. Brumme, M. Brockman, I. Tietjen

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Predictors of HIV Drug-Resistance Mutations in a Large Antiretroviral-Naive Cohort Initiating Triple Antiretroviral Therapy by Harrigan, P. Richard, Hogg, Robert S., Dong, Winnie W. Y., Yip, Benita, Wynhoven, Brian, Woodward, Justin, Brumme, Chanson J., Brumme, Zabrina L., Mo, Theresa, Alexander, Chris S., Montaner, Julio S. G.

“…Objective. The objective of this study was to systematically characterize the incidence and determinants of antiretroviral resistance in the HOMER (Highly…”
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P762 TEMPORAL CHANGES IN HEPATITIS C VIRUS GENOTYPE 3A DISTRIBUTION AMONG PEOPLE WHO INJECT DRUGS IN VANCOUVER, CANADA by Jacka, B, Applegate, T, Poon, A.F, Harrigan, R, Dore, G.J, Olmstead, A, DeBeck, K, Milloy, M.-J, Lamoury, F, Woods, C, Brumme, Z, Dobrer, S, Dias Lima, V, Montaner, J, Joy, J, Marshall, B.D, Kerr, T, Wood, E, Krajden, M, Grebely, J

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Phenotypic Susceptibilities to Tenofovir in a Large Panel of Clinically Derived Human Immunodeficiency Virus Type 1 Isolates by HARRIGAN, P. R, MILLER, M. D, MCKENNA, P, BRUMME, Z. L, LARDER, B. A

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Molecular and Clinical Epidemiology of CXCR4-Using HIV-1 in a Large Population of Antiretroviral-Naive Individuals by Brumme, Zabrina L., Goodrich, James, Mayer, Howard B., Brumme, Chanson J., Henrick, Bethany M., Wynhoven, Brian, Asselin, Jerome J., Cheung, Peter K., Hogg, Robert S., Montaner, Julio S. G., Harrigan, P. Richard

“…ObjectiveWe wished to characterize the epidemiological and clinical correlates of CXCR4-using human immunodeficiency virus type 1 (HIV-1) (“X4 variants”) in a…”
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Changes in Mitochondrial DNA as a Marker of Nucleoside Toxicity in HIV-Infected Patients by Côté, Hélène C.F, Brumme, Zabrina L, Craib, Kevin J.P, Alexander, Christopher S, Wynhoven, Brian, Ting, Lillian, Wong, Hubert, Harris, Marianne, Harrigan, P. Richard, O'Shaughnessy, Michael V, Montaner, Julio S.G

“…This study analyzed changes in mitochondrial DNA relative to nuclear DNA in the peripheral-blood cells of patients infected with the human immunodeficiency…”
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The latent reservoir as a genetically diverse archive recapitulating within-host HIV evolutionary history by B. Jones, N. Kinloch, J. Horacsek, B. Ganase, M. Harris, R. Harrigan, R.B. Jones, M. Brockman, J. Joy, A. Poon, Z. Brumme

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Assay of HIV gp41 amino acid sequence to identify baseline variation and mutation development in patients with virologic failure on enfuvirtide by Loutfy, M.R., Raboud, J.M., Montaner, J.S.G., Antoniou, T., Wynhoven, B., Smaill, F., Rouleau, D., Gill, J., Schlech, W., Brumme, Z.L., Mo, T., Gough, K., Rachlis, A., Harrigan, P.R., Walmsley, S.L.

“…In this study, we retrospectively assessed a gp41 genotypic assay in 404 enfuvirtide-naïve individuals (340 clade B, 64 non-B clade) to determine the…”
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Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1 by Poon, Art F Y, Swenson, Luke C, Dong, Winnie W Y, Deng, Wenjie, Kosakovsky Pond, Sergei L, Brumme, Zabrina L, Mullins, James I, Richman, Douglas D, Harrigan, P Richard, Frost, Simon D W

“…Rapidly evolving viruses such as HIV-1 display extensive sequence variation in response to host-specific selection, while simultaneously maintaining functions…”
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A Simple Screening Approach to Reduce B5701-Associated Abacavir Hypersensitivity on the Basis of Sequence Variation in HIV Reverse Transcriptase by Chui, Celia K. S., Brumme, Zabrina L., Brumme, Chanson J., Yip, Benita, Phillips, Elizabeth J., Montaner, Julio S. G., Harrigan, P. Richard

“…Background. Abacavir hypersensitivity is strongly associated with the human leukocyte antigen (HLA)–B*5701 allele; however, the cost of routine high-resolution…”
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P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity by Boutwell, CL, Schneidewind, A, Brumme, Z, Brockman, M, Streeck, H, Brumme, C, Dudek, T, Kane, K, Kemper, M, Walker, B, Altfeld, M, Allen, T

“…Conclusion Comprehensive analysis of the impact on viral replication capacity of HLA-associated polymorphisms in Gag revealed that mutations in immunodominant…”
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Limited evidence for alterations in Gag-mediated HIV replication capacity over the course of the North American epidemic (1979-present) by Cotton, L, Chopera, D, Penney, K, Carlson, J, Martin, E, Le, A, Kuang, T, Walker, B, Fuchs, J, Buchbinder, S, Wagner, T, John, M, Mallal, S, Koblin, B, Mayer, K, Poon, A, Brockman, M, Brumme, Z

“…Doc number: P157…”
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P09-09. Impact of immune-driven sequence variation in HIV-1 subtype C Gag-Protease on viral fitness and disease progression by Wright, J K, Brockman, MA, Brumme, Z L, Walker, B D, Goulder, P J, Ndung'u, T

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P16-41. Evidence for in vivo immune selection pressure exerted by HLA class I restricted CTL responses to anti-sense encoded HIV sequences by Berger, CT, Carlson, J, Brumme, CJ, Brumme, ZL, Hartman, K, Henry, LM, Kadie, C, Brockman, MA, Harrigan, R, Heckerman, D, Brander, C

“…Doc number: P270…”
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