Search Results - "Brum, S"

Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring by Ashton, Nicholas J., Janelidze, Shorena, Mattsson-Carlgren, Niklas, Binette, Alexa Pichet, Strandberg, Olof, Brum, Wagner S., Karikari, Thomas K., González-Ortiz, Fernándo, Di Molfetta, Guglielmo, Meda, Francisco J., Jonaitis, Erin M., Koscik, Rebecca Langhough, Cody, Karly, Betthauser, Tobey J., Li, Yan, Vanmechelen, Eugeen, Palmqvist, Sebastian, Stomrud, Erik, Bateman, Randall J., Zetterberg, Henrik, Johnson, Sterling C., Blennow, Kaj, Hansson, Oskar

“…Blood biomarkers indicative of Alzheimer’s disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease. Distinctive biomarkers…”
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Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility by Karikari, Thomas K., Ashton, Nicholas J., Brinkmalm, Gunnar, Brum, Wagner S., Benedet, Andréa L., Montoliu-Gaya, Laia, Lantero-Rodriguez, Juan, Pascoal, Tharick Ali, Suárez-Calvet, Marc, Rosa-Neto, Pedro, Blennow, Kaj, Zetterberg, Henrik

“…Well-authenticated biomarkers can provide critical insights into the biological basis of Alzheimer disease (AD) to enable timely and accurate diagnosis,…”
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Plasma phospho-tau in Alzheimer's disease: towards diagnostic and therapeutic trial applications by Gonzalez-Ortiz, Fernando, Kac, Przemysław R, Brum, Wagner S, Zetterberg, Henrik, Blennow, Kaj, Karikari, Thomas K

“…As the leading cause of dementia, Alzheimer's disease (AD) is a major burden on affected individuals, their families and caregivers, and healthcare systems…”
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Efficient removal of amoxicillin and paracetamol from aqueous solutions using magnetic activated carbon by Saucier, Caroline, Karthickeyan, P., Ranjithkumar, V., Lima, Eder C., dos Reis, Glaydson S., de Brum, Irineu A. S.

“…Activated carbon (AC)/CoFe 2 O 4 nanocomposites, MAC-1 and MAC-2, were prepared by a simple pyrolytic method using a mixture of iron(III)/cobalt(II) benzoates…”
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The accuracy and robustness of plasma biomarker models for amyloid PET positivity by Benedet, Andréa L, Brum, Wagner S, Hansson, Oskar, Karikari, Thomas K, Zimmer, Eduardo R, Zetterberg, Henrik, Blennow, Kaj, Ashton, Nicholas J

“…Plasma biomarkers for Alzheimer's disease (AD) have broad potential as screening tools in primary care and disease-modifying trials. Detecting elevated…”
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Test‐retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models by Cullen, Nicholas C., Janelidze, Shorena, Mattsson‐Carlgren, Niklas, Palmqvist, Sebastian, Bittner, Tobias, Suridjan, Ivonne, Jethwa, Alexander, Kollmorgen, Gwendlyn, Brum, Wagner S., Zetterberg, Henrik, Blennow, Kaj, Stomrud, Erik, Hansson, Oskar

“…Introduction The effect of random error on the performance of blood‐based biomarkers for Alzheimer's disease (AD) must be determined before clinical…”
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Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease by Ashton, Nicholas J., Benedet, Andréa L., Pascoal, Tharick A., Karikari, Thomas K., Lantero-Rodriguez, Juan, Brum, Wagner S., Mathotaarachchi, Sulantha, Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Stoops, Erik, Francois, Cindy, Vanmechelen, Eugeen, Gauthier, Serge, Zimmer, Eduardo R., Zetterberg, Henrik, Blennow, Kaj, Rosa-Neto, Pedro

“…Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD)…”
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Recovery of Arapaima sp. populations by community-based management in floodplains of the Purus River, Amazon by Petersen, T. A., Brum, S. M, Rossoni, F., Silveira, G. F. V., Castello, L.

“…In the present study a unique dataset on population abundance in various community‐based management (CBM) and non‐CBM areas is analysed to address the question…”
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A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings by Brum, Wagner S., Cullen, Nicholas C., Therriault, Joseph, Janelidze, Shorena, Rahmouni, Nesrine, Stevenson, Jenna, Servaes, Stijn, Benedet, Andrea L., Zimmer, Eduardo R., Stomrud, Erik, Palmqvist, Sebastian, Zetterberg, Henrik, Frisoni, Giovanni B., Ashton, Nicholas J., Blennow, Kaj, Mattsson-Carlgren, Niklas, Rosa-Neto, Pedro, Hansson, Oskar

“…Blood-based biomarkers for screening may guide tau positrion emissition tomography (PET) scan referrals to optimize prognostic evaluation in Alzheimer’s…”
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Incidence of pale, soft and exudative (PSE) pork meat in reason of extrinsic stress factors by TREVISAN, LAURA, BRUM, JULIANA S.

“…Abstract The incidence of PSE (pale, soft and exudative) pork meat is directly influenced by pre-slaughter handling of animals, compromising meat quality and…”
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Reassessment of the enigmatic crocodyliform "Goniopholis" paulistanus Roxo, 1936: Historical approach, systematic, and description by new materials by Piacentini Pinheiro, André E, Pereira, Paulo Victor Luiz Gomes da Costa, de Souza, Rafael G, Brum, Arthur S, Lopes, Ricardo T, Machado, Alessandra S, Bergqvist, Lílian P, Simbras, Felipe M

“…The Crocodyliformes are the most represented vertebrate clade in the Upper Cretaceous sequences of the Bauru Group, Paraná Basin. However, some of the species…”
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Impact of the COVID-19 pandemic on early career dementia researchers: A global online survey by Bartels, Sara Laureen, Shaaban, C Elizabeth, Brum, Wagner S, Welikovitch, Lindsay A, Folarin, Royhaan, Smith, Adam

“…The World Health Organization recognizes dementia as a public health priority and highlights research as an action to respond to the consequences, with early…”
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Urinary microRNAs expression in prostate cancer diagnosis: a systematic review by Paiva, R. M., Zauli, D. A. G., Neto, B. S., Brum, I. S.

“…Purpose Circulating microRNAs (miRNAs) have been shown to have the potential as noninvasive diagnosis biomarkers in several types of cancers, including…”
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Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease by Lantero-Rodriguez, Juan, Salvadó, Gemma, Snellman, Anniina, Montoliu-Gaya, Laia, Brum, Wagner S, Benedet, Andrea L, Mattsson-Carlgren, Niklas, Tideman, Pontus, Janelidze, Shorena, Palmqvist, Sebastian, Stomrud, Erik, Ashton, Nicholas J, Zetterberg, Henrik, Blennow, Kaj, Hansson, Oskar

“…Novel phosphorylated-tau (p-tau) blood biomarkers (e.g., p-tau181, p-tau217 or p-tau231), are highly specific for Alzheimer's disease (AD), and can track…”
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Art therapy as an adjuvant treatment for depression in elderly women: a randomized controlled trial by Ciasca, Eliana C, Ferreira, Rita C, Santana, Carmen L A, Forlenza, Orestes V, Dos Santos, Glenda D, Brum, Paula S, Nunes, Paula V

“…There are few quantitative studies on art therapy for the treatment of depression. The objective of this study was to evaluate if art therapy is beneficial as…”
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Use of dolphins and caimans as bait for Calophysus macropterus (Lichtenstein, 1819) (Siluriforme: Pimelodidae) in the Amazon by Brum, S. M, Silva, V. M. F, Rossoni, F, Castello, L

“…A new fishery has been developing in the Amazon that uses dolphin and caiman species as bait to catch piracatinga (Calophysus macropterus), having thus the…”
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Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts by Lantero-Rodriguez, Juan, Vrillon, Agathe, Fernández-Lebrero, Aida, Ortiz-Romero, Paula, Snellman, Anniina, Montoliu-Gaya, Laia, Brum, Wagner S, Cognat, Emmanuel, Dumurgier, Julien, Puig-Pijoan, Albert, Navalpotro-Gómez, Irene, García-Escobar, Greta, Karikari, Thomas K, Vanmechelen, Eugeen, Ashton, Nicholas J, Zetterberg, Henrik, Suárez-Calvet, Marc, Paquet, Claire, Blennow, Kaj

“…Cerebrospinal fluid (CSF) p-tau235 is a novel biomarker highly specific of Alzheimer's disease (AD). However, CSF p-tau235 has only been studied in…”
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Plasma and CSF concentrations of N‐terminal tau fragments associate with in vivo neurofibrillary tangle burden by Lantero‐Rodriguez, Juan, Tissot, Cécile, Snellman, Anniina, Servaes, Stijn, Benedet, Andrea L., Rahmouni, Nesrine, Montoliu‐Gaya, Laia, Therriault, Joseph, Brum, Wagner S., Stevenson, Jenna, Lussier, Firoza Z., Bezgin, Gleb, Macedo, Arthur C., Chamoun, Mira, Mathotaarachi, Sulantha S., Pascoal, Tharick A., Ashton, Nicholas J., Zetterberg, Henrik, Neto, Pedro Rosa, Blennow, Kaj

“…INTRODUCTION Fluid biomarkers capable of specifically tracking tau tangle pathology in vivo are greatly needed. METHODS We measured cerebrospinal fluid (CSF)…”
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Effects of time of the day at sampling on CSF and plasma levels of Alzheimer' disease biomarkers by Orduña Dolado, Anna, Stomrud, Erik, Ashton, Nicholas J, Nilsson, Johanna, Quijano-Rubio, Clara, Jethwa, Alexander, Brum, Wagner S, Brinkmalm Westman, Ann, Zetterberg, Henrik, Blennow, Kaj, Janelidze, Shorena, Hansson, Oskar

“…Studies suggest that cerebrospinal fluid (CSF) levels of amyloid-β (Aβ)42 and Aβ40 present a circadian rhythm. However sustained sampling of large volumes of…”
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CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals by Simrén, Joel, Brum, Wagner S, Ashton, Nicholas J, Benedet, Andrea L, Karikari, Thomas K, Kvartsberg, Hlin, Sjons, Emma, Lussier, Firoza Z, Chamoun, Mira, Stevenson, Jenna, Hopewell, Robert, Pallen, Vanessa, Ye, Keqiang, Pascoal, Tharick A, Zetterberg, Henrik, Rosa-Neto, Pedro, Blennow, Kaj

“…Cerebrospinal fluid (CSF) tau biomarkers are reliable diagnostic markers for Alzheimer's disease (AD). However, their strong association with amyloid pathology…”
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