Search Results - "Bruley, Duane F."
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ISOTT from the Beginning: A Tribute to Our Deceased Members (Icons)
Published in Advances in experimental medicine and biology (01-01-2016)“…ISOTT was founded by Drs. Duane F. Bruley and Haim I. Bicher in the state of South Carolina, USA in 1973. The symposium was jointly held at Clemson University…”
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Celebration of the 50th Anniversary of ISOTT (September 27, 2023 Tokyo, Japan) : ISOTT-A Meaningful Idea That Is Successful
Published in Advances in experimental medicine and biology (2024)“…In the early 1960s, I was working as a traditional chemical engineer studying inanimate objects without the slightest clue of the biological world. At that…”
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A Compelling Case for the Use of Perioperative Zymogen Protein C for Increased Patient Safety
Published in Advances in experimental medicine and biology (2016)“…It is imperative to maintain normal blood flow to provide adequate oxygen supply to specific organs and cells, as well as for the removal of metabolic…”
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Case Report: Perioperative Use of Protein C Concentrate for Protein C Deficiency in THA
Published in Clinical orthopaedics and related research (01-07-2010)“…Background Perioperative management of patients with heterozygous protein C deficiency is challenging because of the competing risks of bleeding and recurrent…”
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The founding of ISOTT: the Shamattawa of engineering science and medical science
Published in Advances in experimental medicine and biology (01-01-2014)“…The founding of ISOTT was based upon the blending of Medical and Engineering sciences. This occurrence is portrayed by the Shamattawa, the joining of the…”
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The history of ISOTT
Published in Advances in experimental medicine and biology (2012)Get more information
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Two Consecutive Invasive Surgeries Utilizing Zymogen Protein C (ZPC) That Enhanced Patient Safety and Reduced Costs
Published in Advances in experimental medicine and biology (2021)“…This case report describes a major surgical procedure for a protein C-deficient, hypercoagulable patient who underwent two back-to-back invasive surgeries, hip…”
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Nature's "silver bullet" for anticoagulation: mechanism of Zymogen Protein C to Activated Protein C
Published in Advances in experimental medicine and biology (01-01-2013)“…We have defined the Zymogen Protein C (ZPC) to Activated Protein C (APC) process as the "silver bullet" of blood anticoagulation. This definition suggests that…”
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Pancreaticoduodenectomy using perioperative zymogen protein C to help prevent blood clotting: a trilogy on increased patient safety
Published in Advances in experimental medicine and biology (2013)“…The blood clotting mechanism is a very important and complex physiologic process. Blood flow must be continuous through the blood vessels to provide essential…”
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Zymogen Protein C to prevent clotting without bleeding during invasive medical procedures
Published in Advances in experimental medicine and biology (2011)“…Thrombophilic disorders that predispose patients to develop blood clots can be life-threatening and result in a large economic burden on healthcare…”
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Anticoagulant blood factor deficiencies (protein C)
Published in Advances in experimental medicine and biology (2007)“…Anti-coagulant proteins are essential to maintain blood hemostatis for the supply of oxygen and nutrients to tissue cells and for the removal of toxic…”
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Safer surgery using zymogen protein C concentrate
Published in Advances in experimental medicine and biology (01-01-2010)“…This is the first case (November 12, 2007) of peri-operative use of zymogen protein C (ZPC) for a heterozygote Protein C deficient (50%) patient with…”
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What is tissue engineering? What is ISOTT's role?
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Manipulation of the affinity between protein and metal ions by imidazole and pH for metal affinity purification of protein C from Cohn fraction IV-1
Published in Advances in experimental medicine and biology (2008)“…Protein C (PC) is an important anticoagulant in blood plasma. Cohn Fraction IV-1 (CFIV-1) is an inexpensive PC source but contains a large amount of factor II…”
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Effect of pH and imidazole on protein C purification from Cohn fraction IV-1 by IMAC
Published in Advances in experimental medicine and biology (2007)“…Cohn Fraction IV-1 (CFIV-1) is a by-product (often discarded) of a plasma fractionation process. It retains 90% of Protein C (PC) of plasma but contains…”
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Polyphosphates and other phosphorus-containing polymers for drug delivery applications
Published in Critical reviews in therapeutic drug carrier systems (2003)“…Poly(phosphate ester)s, polyphosphonates, and polyphosphazenes are three classes of phosphorus-containing polymers that have received wide attention over the…”
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Chelator, metal ion and buffer studies for protein C separation
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-05-2002)“…Protein C (PC) is the pivotal anticoagulant and antithrombotic in the human coagulation cascade. PC deficiency can result in major medical problems such as…”
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