Search Results - "Bruguera, Elise S."

Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors by Ikegami, Kentaro, de March, Claire A., Nagai, Maira H., Ghosh, Soumadwip, Do, Matthew, Sharma, Ruchira, Bruguera, Elise S., Lu, Yueyang Eric, Fukutani, Yosuke, Vaidehi, Nagarajan, Yohda, Masafumi, Matsunami, Hiroaki

“…Mammalian odorant receptors are a diverse and rapidly evolving set of G protein-coupled receptors expressed in olfactory cilia membranes. Most odorant…”
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Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether by Bruguera, Elise S., Mahoney, Jacob P., Weis, William I.

“…Many membrane proteins function as dimers or larger oligomers, including transporters, channels, certain signaling receptors, and adhesion molecules. In some…”
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PI(4,5)P 2 -stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling by Mahoney, Jacob P, Bruguera, Elise S, Vasishtha, Mansi, Killingsworth, Lauren B, Kyaw, Saw, Weis, William I

“…In the Wnt-β-catenin pathway, Wnt binding to Frizzled (Fzd) and LRP5 or LRP6 (LRP5/6) co-receptors inhibits the degradation of the transcriptional coactivator…”
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