Targeted next-generation sequencing of circulating free DNA enables non-invasive tumor detection in myxoid liposarcomas

Keywords: Soft tissue sarcoma, Myxoid liposarcoma, Next-generation sequencing, Targeted sequencing, Circulating tumor DNA, ctDNA, Liquid biopsy, Diagnostic biomarker, Intratumor heterogeneity

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Bibliographic Details
Published in:	Molecular cancer Vol. 21; no. 1; p. 50
Main Authors:	Eisenhardt, A E, Schmid, A, Esser, J, Brugger, Z, Lausch, U, Kiefer, J, Braig, M, Runkel, A, Wehrle, J, Claus, R, Bronsert, P, Leithner, A, Liegl-Atzwanger, B, Zeller, J, Papini, R, von Laffert, M, Pfitzner, B M, Koulaxouzidis, G, Giunta, R E, Eisenhardt, S U, Braig, David
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 14-02-2022 BioMed Central BMC
Subjects:	Biopsy Circulating tumor DNA ctDNA DNA DNA sequencing Letter to the Editor Liposarcoma Magnetic resonance imaging Metastases Metastasis Mutation Mutation hot spots Myxoid liposarcoma Next-generation sequencing Patients Plasma Radiation therapy Sarcoma Soft tissue sarcoma Targeted sequencing Tumors Next-generation sequencing Myxoid liposarcoma Soft tissue sarcoma Liquid biopsy Diagnostic biomarker, Intratumor heterogeneity Targeted sequencing Circulating tumor DNA ctDNA
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Description
Summary:	Keywords: Soft tissue sarcoma, Myxoid liposarcoma, Next-generation sequencing, Targeted sequencing, Circulating tumor DNA, ctDNA, Liquid biopsy, Diagnostic biomarker, Intratumor heterogeneity
Bibliography:	SourceType-Other Sources-1 ObjectType-Article-2 content type line 63 ObjectType-Correspondence-1
ISSN:	1476-4598 1476-4598
DOI:	10.1186/s12943-022-01523-x