Search Results - "Bruewer, M."

Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and β-catenin by Mees, S. T, Mennigen, R, Spieker, T, Rijcken, E, Senninger, N, Haier, J, Bruewer, M

“…Background Tight junction (TJ) proteins play a critical role in cellular adhesion, glandular differentiation, and cellular proliferation. The function of these…”
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Current status of laparoscopic surgery for patients with Crohn’s disease by Neumann, P. A., Rijcken, E. J. M., Bruewer, M.

“…Purpose Minimally invasive surgery is increasingly utilized in treatment for refractory or complicated Crohn’s disease, and new developments aim at further…”
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Insulin-like growth factor 1-coated sutures improve anastomotic healing in an experimental model of colitis by Rijcken, E., Fuchs, T., Sachs, L., Kersting, C. M., Bruewer, M., Krieglstein, C. F.

“…Background: Exogenously applied insulin‐like growth factor (rhIGF‐1) may improve normal intestinal healing. This study examined the effect of rhIGF‐1‐coated…”
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Evaluation of clinical need, effectiveness, and safety of the first myosin inhibitor mavacamten in real world patients by Seuthe, K, Feidakis, A, Nies, R, Bruewer, M, Pennig, L, Mons, U, Baldus, S, Pfister, R

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Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms by Bruewer, Matthias, Luegering, Andreas, Kucharzik, Torsten, Parkos, Charles A, Madara, James L, Hopkins, Ann M, Nusrat, Asma

“…It is well known that inflammatory conditions of the intestinal mucosa result in compromised barrier function. Inflammation is characterized by an influx into…”
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Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane by Utech, Markus, Ivanov, Andrei I, Samarin, Stanislav N, Bruewer, Matthias, Turner, Jerrold R, Mrsny, Randall J, Parkos, Charles A, Nusrat, Asma

“…Disruption of epithelial barrier by proinflammatory cytokines such as IFN-gamma represents a major pathophysiological consequence of intestinal inflammation…”
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Interferon‐γ induces internalization of epithelial tight junction proteins via a macropinocytosis‐like process by Bruewer, Matthias, Utech, Markus, Ivanov, Andrei I., Hopkins, Ann M., Parkos, Charles A., Nusrat, Asma

“…ABSTRACTIncreased epithelial permeability is observed in inflammatory states. However, the mechanism by which inflammatory mediators such as IFN‐γ increase…”
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Regulation of the intestinal epithelial barrier by the apical junctional complex by Laukoetter, Mike G, Bruewer, Matthias, Nusrat, Asma

“…PURPOSE OF REVIEWEpithelial intercellular junctions are important components of the epithelial barrier and are compromised in disorders such as Crohnʼs…”
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RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin by Bruewer, Matthias, Hopkins, Ann M, Hobert, Michael E, Nusrat, Asma, Madara, James L

“…Epithelial intercellular junctions regulate cell-cell contact and mucosal barrier function. Both tight junctions (TJs) and adherens junctions (AJs) are…”
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The Adenosine 2b Receptor Is Recruited to the Plasma Membrane and Associates with E3KARP and Ezrin upon Agonist Stimulation by Sitaraman, Shanthi V., Wang, Lixin, Wong, Michelle, Bruewer, Matthias, Hobert, Michael, Yun, C-H., Merlin, Didier, Madara, James L.

“…We have previously shown that adenosine is formed in the intestinal lumen during active inflammation from neutrophil-derived 5′-AMP. Acting through the…”
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Education in laparoscopic surgery: national survey on current strategies and relevance of simulation training by Bonrath, E M, Buckl, L, Brüwer, M, Senninger, N, Rijcken, E

“…Laparoscopic surgery demands from the surgeon specific operative skills. Learning -curves have been described for many procedures in this technique. In order…”
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Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and [beta]-catenin by Mees, S T, Mennigen, R, Spieker, T, Rijcken, E, Senninger, N, Haier, J, Bruewer, M

“…Tight junction (TJ) proteins play a critical role in cellular adhesion, glandular differentiation, and cellular proliferation. The function of these proteins…”
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IFN-Gamma induces apoptosis in inflammation by inhibition of the Wnt-pathway: O-014 by Laukoetter, M, Nava, P, Lee, W, Bruewer, M, Klapproth, J, Babbin, B, Parkos, C, Nusrat, A

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Are leukocytes and CRP early indicators for anastomotic leakage after esophageal resection? by Deitmar, S, Anthoni, C, Palmes, D, Haier, J, Senninger, N, Brüwer, M

“…Anastomotic leaks represent the most common severe postoperative complications after esophagectomy. In this study standard inflammatory laboratory parameters…”
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Preoperative Steroid Administration: Effect on Morbidity among Patients Undergoing Intestinal Bowel Resection for Crohn’s Disease by Bruewer, Matthias, Utech, Markus, Rijcken, Emile J.M., Anthoni, Christoph, Laukoetter, Mike G., Kersting, Sabine, Senninger, Norbert, Krieglstein, Christian F.

“…Long‐term steroid therapy may predispose to increased perioperative morbidity in patients undergoing surgery with bowel anastomoses. The aim of our study was…”
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Immunoblockade of PSGL-1 attenuates established experimental murine colitis by reduction of leukocyte rolling by Rijcken, Emile M, Laukoetter, Mike G, Anthoni, Christoph, Meier, Stephanie, Mennigen, Rudolf, Spiegel, Hans-Ullrich, Bruewer, Matthias, Senninger, Norbert, Vestweber, Dietmar, Krieglstein, Christian F

“…Recruitment of circulating leukocytes into the colonic tissue is a key feature of intestinal inflammation. P-selectin glycoprotein ligand-1 (PSGL-1) and very…”
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Reply to the letter by L. Bonavina regarding our article “Effect of pyloric drainage procedures on gastric passage and bile reflux after esophagectomy with gastric conduit reconstruction” by Palmes, D., Weilinghoff, M., Colombo-Benkmann, M., Senninger, N., Brüwer, M.

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Antigen Transport and Cytoskeletal Characteristics of a Distinct Enterocyte Population in Inflammatory Bowel Diseases by Kersting, Sabine, Bruewer, Matthias, Schuermann, Guido, Klotz, Axel, Utech, Markus, Hansmerten, Matthias, Krieglstein, Christian F., Senninger, Norbert, Schulzke, Joerg-Dieter, Naim, Hassan Y., Zimmer, Klaus-Peter

“…Intestinal antigen uptake is enhanced in inflammatory bowel disease. We analyzed transcellular transport routes of antigens in different compartments of normal…”
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Cerebral vasculitis as rare extraintestinal manifestation in ulcerative colitis: review of the literature and case report by Bonrath, E M, Rijcken, E, Dziewas, R, Vieth, V, Bettenworth, D, Senninger, N, Brüwer, M

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Thoracic epidural anesthesia induces thoracic and abdominal sympathetic block: A-462 by Freise, H., Radke, R., Lauer, S., Bruewer, M., Brodner, G., Van Aken, H., Sielenkaemper, A.

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