Search Results - "Bruening, Jan"

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  1. 1

    Deep learning based assessment of hemodynamics in the coarctation of the aorta: comparison of bidirectional recurrent and convolutional neural networks by Versnjak, Jakob, Yevtushenko, Pavlo, Kuehne, Titus, Bruening, Jan, Goubergrits, Leonid

    Published in Frontiers in physiology (21-02-2024)
    “…The utilization of numerical methods, such as computational fluid dynamics (CFD), has been widely established for modeling patient-specific hemodynamics based…”
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    CT-Based Simulation of Left Ventricular Hemodynamics: A Pilot Study in Mitral Regurgitation and Left Ventricle Aneurysm Patients by Obermeier, Lukas, Vellguth, Katharina, Schlief, Adriano, Tautz, Lennart, Bruening, Jan, Knosalla, Christoph, Kuehne, Titus, Solowjowa, Natalia, Goubergrits, Leonid

    Published in Frontiers in cardiovascular medicine (22-03-2022)
    “…Cardiac CT (CCT) is well suited for a detailed analysis of heart structures due to its high spatial resolution, but in contrast to MRI and echocardiography,…”
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    Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters by Goubergrits, Leonid, Hellmeier, Florian, Bruening, Jan, Spuler, Andreas, Hege, Hans-Christian, Voss, Samuel, Janiga, Gábor, Saalfeld, Sylvia, Beuing, Oliver, Berg, Philipp

    Published in Biomedical engineering online (25-03-2019)
    “…Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured…”
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    Numerical investigation of the impact of branching vessel boundary conditions on aortic hemodynamics by Yevtushenko, Pavlo, Hellmeier, Florian, Bruening, Jan, Kuehne, Titus, Goubergrits, Leonid

    “…CFD has gained significant attention as a tool to model aortic hemodynamics. However, obtaining accurate patient-specific boundary conditions still poses a…”
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    Hemodynamic Evaluation of a Biological and Mechanical Aortic Valve Prosthesis Using Patient‐Specific MRI‐Based CFD by Hellmeier, Florian, Nordmeyer, Sarah, Yevtushenko, Pavlo, Bruening, Jan, Berger, Felix, Kuehne, Titus, Goubergrits, Leonid, Kelm, Marcus

    Published in Artificial organs (01-01-2018)
    “…Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve…”
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    Population-based reference values for 4D flow MRI derived aortic blood flow parameters by Schafstedde, Marie, Jarmatz, Lina, Brüning, Jan, Hüllebrand, Markus, Nordmeyer, Sarah, Harloff, Andreas, Hennemuth, Anja

    Published in Physiological measurement (07-03-2023)
    “… This study assesses age-related differences of thoracic aorta blood flow profiles and provides age- and sex-specific reference values using 4D flow…”
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    Surgical Aortic Valve Replacement: Are We Able to Improve Hemodynamic Outcome? by Yevtushenko, Pavlo, Hellmeier, Florian, Bruening, Jan, Nordmeyer, Sarah, Falk, Volkmar, Knosalla, Christoph, Kelm, Marcus, Kuehne, Titus, Goubergrits, Leonid

    Published in Biophysical journal (17-12-2019)
    “…Aortic valve replacement (AVR) does not usually restore physiological flow profiles. Complex flow profiles are associated with aorta dilatation, ventricle…”
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  10. 10

    Generation of synthetic aortic valve stenosis geometries for in silico trials by Verstraeten, Sabine, Hoeijmakers, Martijn, Tonino, Pim, Brüning, Jan, Capelli, Claudio, van de Vosse, Frans, Huberts, Wouter

    “…In silico trials are a promising way to increase the efficiency of the development, and the time to market of cardiovascular implantable devices. The…”
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    Comparison of rhinomanometric and computational fluid dynamic assessment of nasal resistance with respect to measurement accuracy by Schmidt, Nora, Behrbohm, Hans, Goubergrits, Leonid, Hildebrandt, Thomas, Brüning, Jan

    “…Purpose Computational fluid dynamics (CFD)-based calculation of intranasal airflow became an important method in rhinologic research. Current evidence shows…”
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    Impact of turbulence modeling on the simulation of blood flow in aortic coarctation by Katz, Sarah, Caiazzo, Alfonso, Moreau, Baptiste, Wilbrandt, Ulrich, Brüning, Jan, Goubergrits, Leonid, John, Volker

    “…Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class…”
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  13. 13

    Accessory Replicative Helicases and the Replication of Protein-Bound DNA by Brüning, Jan-Gert, Howard, Jamieson L., McGlynn, Peter

    Published in Journal of molecular biology (12-12-2014)
    “…Complete, accurate duplication of the genetic material is a prerequisite for successful cell division. Achieving this accuracy is challenging since there are…”
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  14. 14

    Assessment of hemodynamic responses to exercise in aortic coarctation using MRI-ergometry in combination with computational fluid dynamics by Schubert, Charlotte, Brüning, Jan, Goubergrits, Leonid, Hennemuth, Anja, Berger, Felix, Kühne, Titus, Kelm, Marcus

    Published in Scientific reports (03-11-2020)
    “…In patients with aortic coarctation it would be desirable to assess pressure gradients as well as information about blood flow profiles at rest and during…”
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    Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity by Brüning, Jan, Hildebrandt, Thomas, Heppt, Werner, Schmidt, Nora, Lamecker, Hans, Szengel, Angelika, Amiridze, Natalja, Ramm, Heiko, Bindernagel, Matthias, Zachow, Stefan, Goubergrits, Leonid

    Published in Scientific reports (28-02-2020)
    “…This study’s objective was the generation of a standardized geometry of the healthy nasal cavity. An average geometry of the healthy nasal cavity was generated…”
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    CT-based comparison of porcine, ovine, and human pulmonary arterial morphometry by Goubergrits, Leonid, Schafstedde, Marie, Cesarovic, Nikola, Szengel, Angelika, Schmitt, Boris, Wiegand, Moritz, Romberg, Jan, Arndt, Andreas, Kuehne, Titus, Brüning, Jan

    Published in Scientific reports (18-11-2023)
    “…To facilitate pre-clinical animal and in-silico clinical trials for implantable pulmonary artery pressure sensors, understanding the respective species…”
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    Uncertainty Quantification for Non-invasive Assessment of Pressure Drop Across a Coarctation of the Aorta Using CFD by Brüning, Jan, Hellmeier, Florian, Yevtushenko, Pavlo, Kühne, Titus, Goubergrits, Leonid

    Published in Cardiovascular engineering and technology (01-12-2018)
    “…Purpose Numerical assessment of the pressure drop across an aortic coarctation using CFD is a promising approach to replace invasive catheter-based…”
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    Overexpression of the Replicative Helicase in Escherichia coli Inhibits Replication Initiation and Replication Fork Reloading by Brüning, Jan-Gert, Myka, Kamila Katarzyna, McGlynn, Peter

    Published in Journal of molecular biology (27-03-2016)
    “…Replicative helicases play central roles in chromosome duplication and their assembly onto DNA is regulated via initiators and helicase loader proteins. The…”
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