Search Results - "Bruening, Jan"
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Deep learning based assessment of hemodynamics in the coarctation of the aorta: comparison of bidirectional recurrent and convolutional neural networks
Published in Frontiers in physiology (21-02-2024)“…The utilization of numerical methods, such as computational fluid dynamics (CFD), has been widely established for modeling patient-specific hemodynamics based…”
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CT-Based Simulation of Left Ventricular Hemodynamics: A Pilot Study in Mitral Regurgitation and Left Ventricle Aneurysm Patients
Published in Frontiers in cardiovascular medicine (22-03-2022)“…Cardiac CT (CCT) is well suited for a detailed analysis of heart structures due to its high spatial resolution, but in contrast to MRI and echocardiography,…”
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CT-Based Analysis of Left Ventricular Hemodynamics Using Statistical Shape Modeling and Computational Fluid Dynamics
Published in Frontiers in cardiovascular medicine (05-07-2022)“…Cardiac computed tomography (CCT) based computational fluid dynamics (CFD) allows to assess intracardiac flow features, which are hypothesized as an early…”
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Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters
Published in Biomedical engineering online (25-03-2019)“…Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured…”
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Numerical investigation of the impact of branching vessel boundary conditions on aortic hemodynamics
Published in Current directions in biomedical engineering (01-09-2017)“…CFD has gained significant attention as a tool to model aortic hemodynamics. However, obtaining accurate patient-specific boundary conditions still poses a…”
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Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment
Published in International journal for computer assisted radiology and surgery (01-10-2019)Get full text
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Hemodynamic Evaluation of a Biological and Mechanical Aortic Valve Prosthesis Using Patient‐Specific MRI‐Based CFD
Published in Artificial organs (01-01-2018)“…Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve…”
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Population-based reference values for 4D flow MRI derived aortic blood flow parameters
Published in Physiological measurement (07-03-2023)“… This study assesses age-related differences of thoracic aorta blood flow profiles and provides age- and sex-specific reference values using 4D flow…”
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Surgical Aortic Valve Replacement: Are We Able to Improve Hemodynamic Outcome?
Published in Biophysical journal (17-12-2019)“…Aortic valve replacement (AVR) does not usually restore physiological flow profiles. Complex flow profiles are associated with aorta dilatation, ventricle…”
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Generation of synthetic aortic valve stenosis geometries for in silico trials
Published in International journal for numerical methods in biomedical engineering (01-01-2024)“…In silico trials are a promising way to increase the efficiency of the development, and the time to market of cardiovascular implantable devices. The…”
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Comparison of rhinomanometric and computational fluid dynamic assessment of nasal resistance with respect to measurement accuracy
Published in International journal for computer assisted radiology and surgery (11-07-2022)“…Purpose Computational fluid dynamics (CFD)-based calculation of intranasal airflow became an important method in rhinologic research. Current evidence shows…”
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Impact of turbulence modeling on the simulation of blood flow in aortic coarctation
Published in International journal for numerical methods in biomedical engineering (01-05-2023)“…Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class…”
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Accessory Replicative Helicases and the Replication of Protein-Bound DNA
Published in Journal of molecular biology (12-12-2014)“…Complete, accurate duplication of the genetic material is a prerequisite for successful cell division. Achieving this accuracy is challenging since there are…”
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Assessment of hemodynamic responses to exercise in aortic coarctation using MRI-ergometry in combination with computational fluid dynamics
Published in Scientific reports (03-11-2020)“…In patients with aortic coarctation it would be desirable to assess pressure gradients as well as information about blood flow profiles at rest and during…”
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Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity
Published in Scientific reports (28-02-2020)“…This study’s objective was the generation of a standardized geometry of the healthy nasal cavity. An average geometry of the healthy nasal cavity was generated…”
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Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge
Published in Medical image analysis (01-04-2022)“…•The Cranial Aneurysm Detection and Analysis Challenge (CADA) provides a benchmarking dataset (3D rotational X-ray angiography) and evaluation framework for:…”
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CT-based comparison of porcine, ovine, and human pulmonary arterial morphometry
Published in Scientific reports (18-11-2023)“…To facilitate pre-clinical animal and in-silico clinical trials for implantable pulmonary artery pressure sensors, understanding the respective species…”
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Uncertainty Quantification for Non-invasive Assessment of Pressure Drop Across a Coarctation of the Aorta Using CFD
Published in Cardiovascular engineering and technology (01-12-2018)“…Purpose Numerical assessment of the pressure drop across an aortic coarctation using CFD is a promising approach to replace invasive catheter-based…”
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Overexpression of the Replicative Helicase in Escherichia coli Inhibits Replication Initiation and Replication Fork Reloading
Published in Journal of molecular biology (27-03-2016)“…Replicative helicases play central roles in chromosome duplication and their assembly onto DNA is regulated via initiators and helicase loader proteins. The…”
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