Search Results - "Brueckner, Christopher T"

Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape by Martin, Constance J, Datta, Abhishek, Littlefield, Christopher, Kalra, Ashish, Chapron, Christopher, Wawersik, Stefan, Dagbay, Kevin B, Brueckner, Christopher T, Nikiforov, Anastasia, Danehy, Jr, Francis T, Streich, Jr, Frederick C, Boston, Christopher, Simpson, Allison, Jackson, Justin W, Lin, Susan, Danek, Nicole, Faucette, Ryan R, Raman, Pichai, Capili, Allan D, Buckler, Alan, Carven, Gregory J, Schürpf, Thomas

“…Despite breakthroughs achieved with cancer checkpoint blockade therapy (CBT), many patients do not respond to anti-programmed cell death-1 (PD-1) due to…”
Get more information

An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis by Jackson, Justin W, Frederick C Streich, Jr, Pal, Ajai, Coricor, George, Boston, Chris, Brueckner, Christopher T, Canonico, Kaleigh, Chapron, Christopher, Cote, Shaun, Dagbay, Kevin B, Danehy, Jr, Francis T, Kavosi, Mania, Kumar, Sandeep, Lin, Susan, Littlefield, Christopher, Looby, Kailyn, Manohar, Rohan, Martin, Constance J, Wood, Marcie, Zawadzka, Agatha, Wawersik, Stefan, Nicholls, Samantha B, Datta, Abhishek, Buckler, Alan, Schürpf, Thomas, Carven, Gregory J, Qatanani, Mohammed, Fogel, Adam I

“…Inhibitors of the transforming growth factor-β (TGF-β) pathway are potentially promising antifibrotic therapies, but nonselective simultaneous inhibition of…”
Get more information