Search Results - "Brudny‐Klöppel, Margarete"

The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam by Wiesinger, Herbert, Klein, Stefan, Rottmann, Antje, Nowotny, Bettina, Riecke, Kai, Gashaw, Isabella, Brudny‐Klöppel, Margarete, Fricke, Robert, Höchel, Joachim, Friedrich, Christian

“…It is known that co‐administration of CYP3A inducers may decrease the effectiveness of oral contraceptives containing progestins as mono‐preparations or…”
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Blood stability testing: European Bioanalysis Forum view on current challenges for regulated bioanalysis by Freisleben, Achim, Brudny-Klöppel, Margarete, Mulder, Hans, de Vries, Ronald, de Zwart, Marcel, Timmerman, Philip

“…Since 2008, blood stability testing has gained considerable attention in the European Bioanalysis Forum (EBF) with discussions aiming to align processes,…”
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Workshop/Conference Report on EMA Draft Guideline on Validation of Bioanalytical Methods by Blume, Henning, Brendel, Erich, Brudny-Klöppel, Margarete, Grebe, Sylvia, Lausecker, Berthold, Rohde, Gabriele, Siethoff, Christoph

“…This is a summary report of the workshop on the EMA Draft Guideline on Validation of Bioanalytical Methods held April 15–16th 2010 in Brussels (Belgium) and…”
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Identification of 3 alpha-hydroxy-cyproterone acetate as a metabolite of cyproterone acetate in the bile of female rats and the potential of this and other already known or putative metabolites to form DNA adducts in vitro by Kerdar, R S, Baumann, A, Brudny-Klöppel, M, Biere, H, Blode, H, Kuhnz, W

“…Cyproterone acetate (CPA) is a synthetic steroid hormone used in the therapy of prostate cancer in men and different forms of acne and hirsutism in women. CPA…”
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