Search Results - "Bruckner, Robert C."

Identification of the Oxygen Activation Site in Monomeric Sarcosine Oxidase: Role of Lys265 in Catalysis by Zhao, Guohua, Bruckner, Robert C, Jorns, Marilyn Schuman

“…Monomeric sarcosine oxidase (MSOX) catalyzes the oxidation of N-methylglycine and contains covalently bound FAD that is hydrogen bonded at position N(5) to…”
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Probing Oxygen Activation Sites in Two Flavoprotein Oxidases Using Chloride as an Oxygen Surrogate by Kommoju, Phaneeswara-Rao, Chen, Zhi-wei, Bruckner, Robert C, Mathews, F. Scott, Jorns, Marilyn Schuman

“…A single basic residue above the si-face of the flavin ring is the site of oxygen activation in glucose oxidase (GOX) (His516) and monomeric sarcosine oxidase…”
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Pleiotropic Impact of a Single Lysine Mutation on Biosynthesis of and Catalysis by N-Methyltryptophan Oxidase by Bruckner, Robert C, Winans, Jennifer, Jorns, Marilyn Schuman

“…N-Methyltryptophan oxidase (MTOX) contains covalently bound FAD. N-Methyltryptophan binds in a cavity above the re face of the flavin ring. Lys259 is located…”
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Spectral and Kinetic Characterization of Intermediates in the Aromatization Reaction Catalyzed by NikD, an Unusual Amino Acid Oxidase by Bruckner, Robert C, Jorns, Marilyn Schuman

“…The flavoenzyme nikD, a 2-electron acceptor, catalyzes a remarkable aromatization of piperideine-2-carboxylate (P2C) to picolinate, an essential component of…”
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Coupled Kinetics of ATP and Peptide Hydrolysis by Escherichia coli FtsH Protease by Bruckner, Robert C, Gunyuzlu, Paul L, Stein, Ross L

“…FtsH from Escherichia coli is an ATP- and Zn2+-dependent integral membrane protease that is involved in the degradation of regulatory proteins such as σ32 and…”
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Probing the Role of Active Site Residues in NikD, an Unusual Amino Acid Oxidase That Catalyzes an Aromatization Reaction Important in Nikkomycin Biosynthesis by Kommoju, Phaneeswara-Rao, Bruckner, Robert C, Ferreira, Patricia, Jorns, Marilyn Schuman

“…NikD catalyzes a remarkable aromatization reaction that converts piperideine 2-carboxylate (P2C) to picolinate, a key component of the nonribosomal peptide in…”
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NikD, an Unusual Amino Acid Oxidase Essential for Nikkomycin Biosynthesis: Structures of Closed and Open Forms at 1.15 and 1.90 Å Resolution by Carrell, Christopher J., Bruckner, Robert C., Venci, David, Zhao, Gouhua, Jorns, Marilyn Schuman, Mathews, F. Scott

“…NikD is an unusual amino-acid-oxidizing enzyme that contains covalently bound FAD, catalyzes a 4-electron oxidation of piperideine-2-carboxylic acid to…”
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Biosynthesis of Covalently Bound Flavin:  Isolation and in Vitro Flavinylation of the Monomeric Sarcosine Oxidase Apoprotein by Hassan-Abdallah, Alshaimaa, Bruckner, Robert C, Zhao, Guohua, Jorns, Marilyn Schuman

“…The covalently bound FAD in native monomeric sarcosine oxidase (MSOX) is attached to the protein by a thioether bond between the 8α-methyl group of the flavin…”
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Factors That Affect Oxygen Activation and Coupling of the Two Redox Cycles in the Aromatization Reaction Catalyzed by NikD, an Unusual Amino Acid Oxidase by Kommoju, Phaneeswara-Rao, Bruckner, Robert C, Ferreira, Patricia, Carrell, Christopher J, Mathews, F. Scott, Jorns, Marilyn Schuman

“…NikD is a flavoprotein oxidase that catalyzes the oxidation of piperideine-2-carboxylate (P2C) to picolinate in a remarkable aromatization reaction comprising…”
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A Mobile Tryptophan Is the Intrinsic Charge Transfer Donor in a Flavoenzyme Essential for Nikkomycin Antibiotic Biosynthesis by Bruckner, Robert C, Zhao, Gouhua, Ferreira, Patricia, Jorns, Marilyn Schuman

“…The flavoenzyme nikD is required for the biosynthesis of nikkomycin antibiotics. NikD exhibits an unusual long wavelength absorption band attributed to a…”
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Nikkomycin Biosynthesis:  Formation of a 4-Electron Oxidation Product during Turnover of NikD with Its Physiological Substrate by Bruckner, Robert C, Zhao, Guohua, Venci, David, Jorns, Marilyn Schuman

“…Nikkomycins are peptidyl nucleoside antibiotics that act as therapeutic antifungal agents in humans and easily degraded insecticides in agriculture. The…”
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COMPARISON OF SNAKE VENOM REPROLYSIN AND MATRIX METALLOPROTEINASES AS MODELS OF TNF-α CONVERTING ENZYME by Van Dyk, Drew E, Marchand, Petra, Bruckner, Robert C, Fox, Jay W, Jaffee, Bruce D, Gunyuzlu, Paul L, Davis, Gary L, Nurnberg, Sherrill, Covington, Maryanne, Decicco, Carl P, Trzaskos, James M, Magolda, Ronald L, Copeland, Robert A

“…The reprolysin ht-d was compared to several human MMPs for the ability to cleave a peptide substrate representing the processing site of human pro-TNF. The…”
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Recombination in vitro Between Herpes Simplex Virus Type 1 a Sequences by Bruckner, Robert C., Dutch, Rebecca Ellis, Zemelman, Boris V., Mocarski, Edward S., Lehman, I. R.

“…We have partially purified an activity from extracts of cells infected with herpes simplex virus type 1 that mediates recombination between repeated copies of…”
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NikD, an Unusual Amino Acid Oxidase Essential for Nikkomycin Biosynthesis: Structures of Closed and Open Forms at 1.15 and 1.90 Aa Resolution by Carrell, Christopher J, Bruckner, Robert C, Venci, David, Zhao, Gouhua, Jorns, Marilyn Schuman, Mathews, FScott

“…NikD is an unusual amino-acid-oxidizing enzyme that contains covalently bound FAD, catalyzes a 4-electron oxidation of piperideine-2-carboxylic acid to…”
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The herpes simplex virus 1 origin binding protein: a DNA helicase by BRUCKNER, R. C, CRUTE, J. J, DODSON, M. S, LEHMAN, I. R

“…A recombinant herpes simplex 1 origin binding protein, the product of the herpes UL9 gene, has been overexpressed in mammalian cells and purified to near…”
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Herpes simplex virus type 1 recombination: role of DNA replication and viral a sequences by DUTCH, R. E, BRUCKNER, R. C, MOCARSKI, E. S, LEHMAN, I. R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The FLP Recombinase of the Yeast 2-μ m Plasmid: Characterization of Its Recombination Site by Senecoff, Julie F., Bruckner, Robert C., Cox, Michael M.

“…The minimal size of the recombination site required for efficient FLP recombinase-catalyzed recombination in vitro is no more than 28 base pairs, which…”
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Variant cDNA Sequences of Human ATP:Citrate Lyase: Cloning, Expression, and Purification from Baculovirus-Infected Insect Cells by Lord, Kenneth A., Wang, Xin-Min, Simmons, S.Jill, Bruckner, Robert C., Loscig, Jane, O'Connor, Bernard, Bentley, Ross, Smallwood, Angela, Chadwick, Christopher C., Stevis, Panayiotis E., Ciccarelli, Richard B.

“…ATP:citrate lyase (ACL) is a major generator of cytosolic acetyl-coenzymeA, which is required for both fatty acid and cholesterol biosynthesis. The human ACL…”
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Herpes simplex-1 helicase-primase. Identification of two nucleoside triphosphatase sites that promote DNA helicase action by Crute, J.J., Bruckner, R.C., Dodson, M.S., Lehman, I.R.

“…Herpes simplex virus type 1 (HSV-1) encodes a heterotrimeric helicase-primase comprised of the products of the UL5, UL8, and UL52 genes (Crute, J. J., and…”
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The histone-like H protein of Escherichia coli is ribosomal protein S3 by BRUCKNER, R. C, COX, M. M

“…We report the purification of four proteins from Escherichia coli that stimulate or inhibit inter- and/or intramolecular recombination promoted by the yeast…”
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