Search Results - "Brucker, SY"
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Interpretation of somatic POLE mutations in endometrial carcinoma
Published in The Journal of pathology (01-03-2020)“…Pathogenic somatic missense mutations within the DNA polymerase epsilon (POLE) exonuclease domain define the important subtype of ultramutated tumours…”
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Clinicopathological and molecular characterisation of ‘multiple‐classifier’ endometrial carcinomas
Published in The Journal of pathology (01-03-2020)“…Endometrial carcinoma (EC) molecular classification based on four molecular subclasses identified in The Cancer Genome Atlas (TCGA) has gained relevance in…”
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Neovagina creation methods and their potential impact on subsequent uterus transplantation: a review
Published in BJOG : an international journal of obstetrics and gynaecology (01-10-2019)“…Congenital uterovaginal aplasia commonly occurs in Mayer–Rokitansky–Küster–Hauser syndrome. Various methods of neovagina creation exist, including nonsurgical…”
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Abstract P1-01-16: Detection of disseminated tumor cells in DCIS patients impacts local recurrence
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background Recently it was shown that tumor cell dissemination is an early event in breast cancer progression (Hosseini et al., Nature 2016). This has…”
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1570 Defining Target Scores and Bench Marks for a Minimal Invasive Surgery (Mic) Skills-Training to Add Objective Evaluation to the Certification Process of the German Gynecological Endoscopy Working Group (Age)
Published in Journal of minimally invasive gynecology (01-11-2019)“…To objectively enhance and add individual manual dexterity skills to the MIC certification of the german Gynecological Endoscopy Working group (AGE)…”
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De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017
Published in ANNALS OF ONCOLOGY (01-10-2018)Get full text
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Influence of side-effects on early therapy persistence with letrozole in post-menopausal patients with early breast cancer: Results of the prospective EvAluate-TM study
Published in European journal of cancer (1990) (01-06-2018)“…Endocrine treatment (ET) with an aromatase inhibitor (AI) is the treatment of choice in post-menopausal patients with hormone receptor–positive early breast…”
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Vaginal prevalence of human papillomavirus infections in women with uterovaginal aplasia before and after laparoscopically assisted creation of a neovagina: a prospective epidemiological observational study
Published in BJOG : an international journal of obstetrics and gynaecology (01-01-2019)“…Objective To study vaginal as opposed to cervical human papillomavirus (HPV) acquisition with regard to true prevalence, HPV types, and the role of co‐factors…”
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Abstract P3-01-14: A nomogram to predict the likelihood of axillary non-sentinel lymph node metastases in sentinel lymph node positive primary breast cancer patients
Published in Cancer research (Chicago, Ill.) (15-02-2016)“…Abstract Background: Completion of axillary lymph node dissection (ALND) was long lasting standard in patients with non-metastatic primary breast cancer (PBC)…”
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Abstract OT1-11-02: PRAEGNANT - Real world evidence, translational research, big and smart data: A prospective academic translational research network for the optimization of the oncological health care quality in the adjuvant and advanced/ metastatic setting (NCT02338167)
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Background During the last decades the treatment of advanced breast cancer (ABC) patients has improved due to a variety of new treatment strategies…”
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Abstract P6-17-22: Progression free survival (PFS) and overall survival (OS) of patients treated with trastuzumab emtansine (T-DM1) after previous treatment with pertuzumab in patients with advanced breast cancer (NCT02338167)
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Background Studies leading to the approval of trastuzumab emtansine (T-DM1) have been conducted without pertuzumab as previous therapy. Therefore data…”
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Abstract P6-17-37: Therapy landscape of patients with metastatic, HER2 positive breast cancer - Data from the real world breast cancer registry PRAEGNANT (NCT02338167)
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Purpose: This analysis describes comprehensive real-world data concerning the use of anti-HER2 therapies in HER2 positive metastatic breast cancer…”
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Abstract P3-11-05: Reliability and acceptance of e-based survey instruments for measuring patient reported outcomes (PRO) in breast cancer patients: First results of the ePROCOM study
Published in Cancer research (Chicago, Ill.) (15-02-2017)“…Abstract Introduction Especially in oncology patients, Patient Reported Outcomes (PRO) play an increasingly important role to measure subjectively perceived…”
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Abstract GS1-06: Extended adjuvant bisphosphonate treatment over five years in early breast cancer does not improve disease-free and overall survival compared to two years of treatment: Phase III data from the SUCCESS A study
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background: A recent meta-analysis has reported benefits of adjuvant bisphosphonate treatment in early breast cancer patients with improved breast…”
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Abstract P6-11-10: Impact of disease progression on health-related quality of life in patients with metastatic breast cancer in the PRAEGNANT breast cancer registry
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background: Improved progression-free survival is considered as treatment goal for patients with metastatic breast cancer (MBC) since it is assumed to…”
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Abstract GS5-07: International pooled analysis of the prognostic impact of disseminated tumor cells from the bone marrow in early breast cancer: Results from the PADDY study
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Introduction As early breast cancer might relapse even after complete removal of breast and lymphnodes, the disease must persist in secondary sites…”
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Abstract PD1-02: Cancer predisposition genes in metastatic breast cancer – Association with metastatic pattern, prognosis, patient and tumor characteristics
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background New treatment strategies for metastatic breast cancer (mBC) are mainly driven by therapies against specific targets. BRCA mutations are one…”
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Abstract P3-11-07: Factors associated with first line chemotherapy use in patients with hormone receptor positive, HER2 negative metastatic breast cancer – data from the PRAEGNANT breast cancer registry
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background For breast cancer patients with metastases which are not life threatening national and international guidelines recommend the exhaustion of…”
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Abstract P5-21-09: Overall survival of metastatic breast cancer patients – data from the PRAEGNANT breast cancer registry
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Abstract Background Breast Cancer registries can help to understand how patient groups are treated outside clinical trials and what outcome is to expected for…”
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