Search Results - "Bruce, Iain"

The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate by Harman, Nicola L, Bruce, Iain A, Kirkham, Jamie J, Tierney, Stephanie, Callery, Peter, O'Brien, Kevin, Bennett, Alex M D, Chorbachi, Raouf, Hall, Per N, Harding-Bell, Anne, Parfect, Victoria H, Rumsey, Nichola, Sell, Debbie, Sharma, Ravi, Williamson, Paula R

“…Approximately 75% of children with cleft palate (CP) have Otitis Media with Effusion (OME) histories. Evidence for the effective management of OME in these…”
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Mixed Reality Enhanced Otolaryngology Case‐Based Learning: A Randomized Educational Study by Malik, Rukhnoor, Abbas, Jonathan R., Jayarajah, Ceyon, Bruce, Iain A., Tolley, Neil

“…Introduction The COVID‐19 pandemic has caused unprecedented disruptions to medical education. Education in medical specialties, such as otolaryngology faces…”
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The benefits of preserving residual hearing following cochlear implantation: a systematic review by Schaefer, Simone, Sahwan, Maryam, Metryka, Aleksandra, Kluk, Karolina, Bruce, Iain A.

“…Systematically review the current literature for evidence on the "real-life" benefits of hearing preservation cochlear implantation (HPCI) for children and…”
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Substrate accumulation and extracellular matrix remodelling promote persistent upper airway disease in mucopolysaccharidosis patients on enzyme replacement therapy by Pal, Abhijit Ricky, Mercer, Jean, Jones, Simon A, Bruce, Iain A, Bigger, Brian W

“…Mucopolysaccharide diseases are a group of lysosomal storage disorders caused by deficiencies of hydrolase enzymes, leading to pathological glycosaminoglycan…”
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MOMENT--Management of Otitis Media with Effusion in Cleft Palate: protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey by Harman, Nicola L, Bruce, Iain A, Callery, Peter, Tierney, Stephanie, Sharif, Mohammad Owaise, O'Brien, Kevin, Williamson, Paula R

“…Cleft palate (CP) has an incidence of approximately 1 in 700. Children with CP are also susceptible to otitis media with effusion (OME), with approximately 90%…”
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Can MRI biomarkers for hearing loss in enlarged vestibular aqueduct be measured reproducibly? by Saeed, Haroon S, Rajai, Azita, Dixon, Rachel, Kapadia, Tejas, Bruce, Iain A, Stivaros, Stavros

“…Morphological features of an enlarged endolymphatic duct (ED) and sac (ES) are imaging biomarkers for genotype and hearing loss phenotype. We determine which…”
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Simultaneous and inherent correction of B 0 and eddy-current induced distortions in high-resolution diffusion MRI using reversed polarity gradients and multiplexed sensitivity encoding (RPG-MUSE) by Bruce, Iain P, Petty, Christopher, Song, Allen W

“…In diffusion MRI (dMRI), static magnetic field (B ) inhomogeneity and time varying gradient eddy currents induce spatial distortions in reconstructed images…”
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Column-based cortical depth analysis of the diffusion anisotropy and radiality in submillimeter whole-brain diffusion tensor imaging of the human cortical gray matter in vivo by Ma, Yixin, Bruce, Iain P., Yeh, Chun-Hung, Petrella, Jeffrey R., Song, Allen W., Truong, Trong-Kha

“…•Fractional anisotropy (FA) and radiality index (RI) sampled along cortical columns.•FA local max/min and RI max at intermediate cortical depths in most…”
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[Corrigendum] A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties by Han, Xiaofeng, Du, Fangfang, Jiang, Li, Zhu, Yifei, Chen, Zhen, Liu, Yanjun, Hong, Tingting, Wang, Teng, Mao, Yong, Wu, Xiaohong, Bruce, Iain, Jin, Jian, Ma, Xin, Hua, Dong

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MiR-489 regulates chemoresistance in breast cancer via epithelial mesenchymal transition pathway by Jiang, Li, He, Dongxu, Yang, Dantong, Chen, Zhen, Pan, Qiongxi, Mao, Aiqin, Cai, Yanfei, Li, Xiyuan, Xing, Hui, Shi, Mei, Chen, Yun, Bruce, Iain C., Wang, Teng, Jin, Linfang, Qi, Xiaowei, Hua, Dong, Jin, Jian, Ma, Xin

“…•miR-489 was significantly suppressed in MCF-7/ADM cells compared with parental control MCF-7/WT cells.•Forced-expression of miR-489 reversed the…”
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How are trial outcomes prioritised by stakeholders from different regions? Analysis of an international Delphi survey to develop a core outcome set in gastric cancer surgery by Alkhaffaf, Bilal, Metryka, Aleksandra, Blazeby, Jane M, Glenny, Anne-Marie, Williamson, Paula R, Bruce, Iain A

“…International stakeholder participation is important in the development of core outcome sets (COS). Stakeholders from varying regions may value health outcomes…”
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Rapid Point-of-Care Genotyping to Avoid Aminoglycoside-Induced Ototoxicity in Neonatal Intensive Care by McDermott, John H, Mahaveer, Ajit, James, Rachel A, Booth, Nicola, Turner, Mark, Harvey, Karen E, Miele, Gino, Beaman, Glenda M, Stoddard, Duncan C, Tricker, Karen, Corry, Rachel J, Garlick, Julia, Ainsworth, Shaun, Beevers, Thomas, Bruce, Iain A, Body, Richard, Ulph, Fiona, MacLeod, Rhona, Roberts, Peter L, Wilson, Paul M, Newman, William G

“…Aminoglycosides are commonly prescribed antibiotics used for the treatment of neonatal sepsis. The MT-RNR1 m.1555A>G variant predisposes to profound…”
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Mucopolysaccharidosis type II: European recommendations for the diagnosis and multidisciplinary management of a rare disease by Scarpa, Maurizio, Almássy, Zsuzsanna, Beck, Michael, Bodamer, Olaf, Bruce, Iain A, De Meirleir, Linda, Guffon, Nathalie, Guillén-Navarro, Encarna, Hensman, Pauline, Jones, Simon, Kamin, Wolfgang, Kampmann, Christoph, Lampe, Christina, Lavery, Christine A, Teles, Elisa Leão, Link, Bianca, Lund, Allan M, Malm, Gunilla, Pitz, Susanne, Rothera, Michael, Stewart, Catherine, Tylki-Szymańska, Anna, van der Ploeg, Ans, Walker, Robert, Zeman, Jiri, Wraith, James E

“…Mucopolysaccharidosis type II (MPS II) is a rare, life-limiting, X-linked recessive disease characterised by deficiency of the lysosomal enzyme…”
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3D-MB-MUSE: A robust 3D multi-slab, multi-band and multi-shot reconstruction approach for ultrahigh resolution diffusion MRI by Bruce, Iain P., Chang, Hing-Chiu, Petty, Christopher, Chen, Nan-Kuei, Song, Allen W.

“…Recent advances in achieving ultrahigh spatial resolution (e.g. sub-millimeter) diffusion MRI (dMRI) data have proven highly beneficial in characterizing…”
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Simultaneous and inherent correction of B0 and eddy-current induced distortions in high-resolution diffusion MRI using reversed polarity gradients and multiplexed sensitivity encoding (RPG-MUSE) by Bruce, Iain P., Petty, Christopher, Song, Allen W.

“…In diffusion MRI (dMRI), static magnetic field (B0) inhomogeneity and time varying gradient eddy currents induce spatial distortions in reconstructed images…”
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Hearing preservation in paediatric cochlear implantation with the Nucleus Slim Straight Electrode - our experience by Schaefer, Simone, Sladen, Mark, Nichani, Jaya, Millward, Kerri, Lockley, Morag, O'Driscoll, Martin, Kluk, Karolina, Bruce, Iain A

“…to evaluate the levels of successful hearing preservation and preservation of functional hearing following cochlear implantation (HPCI) in children using the…”
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What is Virtual Reality? A healthcare-focused systematic review of definitions by Abbas, Jonathan R, O'Connor, Alexander, Ganapathy, Eshwar, Isba, Rachel, Payton, Antony, McGrath, Brendan, Tolley, Neil, Bruce, Iain A

“…•There has been a rapid acceleration in healthcare related virtual reality research in the last five years.•Terminology around virtual reality technology is…”
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Novel approach for tracheal resection in Morquio a syndrome with end-stage critical airway obstruction: a UK case series by Kenth, Johnny, Maughan, Elizabeth, Butler, Colin R, Gabrie, Jasleen, Rouhani, Maral, Silver, Benjamin, Ogunbiyi, Olumide K, Wilkinson, Stuart, Nandi, Reema, Walker, Robert, Muthialu, Nagarajan, Jones, Simon, Hewitt, Richard, Bruce, Iain A

“…Mucopolysaccharidosis (MPS) type IVA is a rare lysosomal storage disorder caused by aberrations of the N-acetyl-galactosamine-6-sulfatase (GALNS) enzyme. MPS…”
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Microvesicles mediate transfer of P-glycoprotein to paclitaxel-sensitive A2780 human ovarian cancer cells, conferring paclitaxel-resistance by Zhang, Fang-fang, Zhu, Yi-fei, Zhao, Qian-nan, Yang, Dan-tong, Dong, Ye-ping, Jiang, Li, Xing, Wei-xing, Li, Xi-yuan, Xing, Hui, Shi, Mei, Chen, Yun, Bruce, Iain C, Jin, Jian, Ma, Xin

“…The overexpression of P-glycoprotein (P-gp) causes resistance to chemotherapy in human ovarian cancer. However, the underlying mechanism remains unclear. In…”
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Improving safety for day case adenotonsillectomy in paediatric obstructive sleep apnoea by Heward, Elliot, Bateman, Neil, Schaefer, Simone, Bruce, Iain A., Rajai, Azita, Vetuz, Glenn, Ormandy, Danielle, Doherty, Catherine

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