Search Results - "Bruce, C. R."

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding by Turner, N., Kowalski, G. M., Leslie, S. J., Risis, S., Yang, C., Lee-Young, R. S., Babb, J. R., Meikle, P. J., Lancaster, G. I., Henstridge, D. C., White, P. J., Kraegen, E. W., Marette, A., Cooney, G. J., Febbraio, M. A., Bruce, C. R.

“…Aims/hypothesis While it is well known that diet-induced obesity causes insulin resistance, the precise mechanisms underpinning the initiation of insulin…”
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Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase by Matthews, V. B, Åström, M.-B, Chan, M. H. S, Bruce, C. R, Krabbe, K. S, Prelovsek, O, Åkerström, T, Yfanti, C, Broholm, C, Mortensen, O. H, Penkowa, M, Hojman, P, Zankari, A, Watt, M. J, Bruunsgaard, H, Pedersen, B. K, Febbraio, M. A

“…Aims/hypothesis Brain-derived neurotrophic factor (BDNF) is produced in skeletal muscle, but its functional significance is unknown. We aimed to determine the…”
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Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance by Matthews, V. B, Allen, T. L, Risis, S, Chan, M. H. S, Henstridge, D. C, Watson, N, Zaffino, L. A, Babb, J. R, Boon, J, Meikle, P. J, Jowett, J. B, Watt, M. J, Jansson, J.-O, Bruce, C. R, Febbraio, M. A

“…Aims/hypothesis The role of IL-6 in the development of obesity and hepatic insulin resistance is unclear and still the subject of controversy. We aimed to…”
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Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide by Watt, M. J., Barnett, A. C., Bruce, C. R., Schenk, S., Horowitz, J. F., Hoy, A. J.

“…Aims/hypothesis Plasma ceramide concentrations correlate with insulin sensitivity, inflammation and atherosclerotic risk. We hypothesised that plasma ceramide…”
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The role of adipokines as regulators of skeletal muscle fatty acid metabolism and insulin sensitivity by Dyck, D. J., Heigenhauser, G. J. F., Bruce, C. R.

“…Several adipose‐derived cytokines (adipokines) have been suggested to act as a link between accumulated fat mass and altered insulin sensitivity. Resistin and…”
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PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications by Lancaster, G. I., Kammoun, H. L., Kraakman, M. J., Kowalski, G. M., Bruce, C. R., Febbraio, M. A.

“…Protein kinase R (PKR) has previously been suggested to mediate many of the deleterious consequences of a high-fat diet (HFD). However, previous studies have…”
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Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice by Henstridge, D. C., Bruce, C. R., Pang, C. P., Lancaster, G. I., Allen, T. L., Estevez, E., Gardner, T., Weir, J. M., Meikle, P. J., Lam, K. S. L., Xu, A., Fujii, N., Goodyear, L. J., Febbraio, M. A.

“…Aims/hypothesis Although skeletal muscle insulin resistance has been associated with activation of c-Jun N-terminal kinase (JNK), whether increased JNK…”
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Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice by Kowalski, G. M, Nicholls, H. T, Risis, S, Watson, N. K, Kanellakis, P, Bruce, C. R, Bobik, A, Lancaster, G. I, Febbraio, M. A

“…Aims/hypothesis Recent work has identified the important roles of M1 pro-inflammatory and M2 anti-inflammatory macrophages in the regulation of insulin…”
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Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with Type 2 diabetes by BRUCE, C. R, KRIKETOS, A. D, COONEY, G. J, HAWLEY, J. A

“…We determined the effect of exercise training on insulin sensitivity and muscle lipids (triglyceride [TG(m)] and long-chain fatty acyl CoA [LCACoA]…”
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The polychlorinated dibenzofuran fingerprint of iron ore sinter plant: Its persistence with suppressant and alternative fuel addition by Thompson, Dennis, Ooi, Tze C., Anderson, David R., Fisher, Ray, Ewan, Bruce C.R.

“…An earlier demonstration that the relative concentrations of isomers of polychlorinated dibenzofuran do not vary as the flamefront of an iron ore sinter plant…”
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Interleukin-6 and tumor necrosis factor-α are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness by CAREY, A. L, BRUCE, C. R, SACCHETTI, M, ANDERSON, M. J, OLSEN, D. B, SALTIN, B, HAWLEY, J. A, FEBBRAIO, M. A

“…Our aim was to examine the possible direct relationship of interleukin-6 and TNFalpha with insulin sensitivity in humans. We carried out two series of…”
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A Group Additivity Algorithm for Polychlorinated Dibenzofurans Derived from Selected DFT Analyses by Thompson, Dennis, Ewan, Bruce C. R

“…The difficulty in measuring the heats of combustion of polychlorinated dibenzofurans (PCDFs) has resulted in a shortage of data on their heats of formation,…”
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Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes : effect of interleukin-6 infusion by CAREY, A. L, WOLSK PETERSEN, E, BRUCE, C. R, SOUTHGATE, R. J, PILEGAARD, H, HAWLEY, J. A, PEDERSEN, B. K, FEBBRAIO, M. A

“…We compared metabolic gene expression in adipose tissue and skeletal muscle from patients with type 2 diabetes and from well-matched healthy control subjects…”
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Flawed Assumptions: Ethical Problems With Proposed Presumed Consent Legislation by Bruce, C. R., Koch, P.

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Measurements of the solubility of sulphur dioxide in water for the sulphur family of thermochemical cycles by Shaw, Andrew C., Romero, Moises A., Elder, Rachael H., Ewan, Bruce C.R., Allen, Ray W.K.

“…In recent years, the Hybrid Sulphur (HyS) and Sulphur Iodine (SI) cycles have emerged as promising routes for the massive scale thermochemical production of…”
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Removal of vapour phase PCDD/Fs in electric arc furnace steelmaking emissions by sorption using plastics by Ooi, Tze Chean, Ewan, Bruce C.R., Cliffe, Keith R., Anderson, David R., Fisher, Raymond, Thompson, Dennis

“…Plastics are potentially suitable for the removal of vapour phase PCDD/Fs in emissions from the electric arc furnace (EAF) steelmaking process. Three different…”
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Enhancement of 2000-m rowing performance after caffeine ingestion by BRUCE, Clinton R, ANDERSON, Megan E, FRASER, Steven F, STEPTO, Nigel K, KLEIN, Rudi, HOPKINS, William G, HAWLEY, John A

“…To investigate the effect of caffeine ingestion on short-term endurance performance in competitive rowers. In this randomized double-blind crossover study,…”
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Hazard perception skills of young drivers with Attention Deficit Hyperactivity Disorder (ADHD) can be improved with computer based driver training: An exploratory randomised controlled trial by Bruce, C.R., Unsworth, C.A., Dillon, M.P., Tay, R., Falkmer, T., Bird, P., Carey, L.M.

“…•The hazard perception skills of young drivers diagnosed with Attention deficit hyperactivity disorder improved following training and were in part…”
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The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats by WADLEY, G. D, BRUCE, C. R, KONSTANTOPOULOS, N, MACAULAY, S. L, HOWLETT, K. F, HAWLEY, J. A, CAMERON-SMITH, D

“…Recruitment of the protein c-Cbl to the insulin receptor (IR) and its tyrosine phosphorylation via a pathway that is independent from phosphatidylinositol…”
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Growing healthy muscles to optimise metabolic health into adult life by Bayol, S A, Bruce, C R, Wadley, G D

“…The importance of skeletal muscle for metabolic health and obesity prevention is gradually gaining recognition. As a result, interventions are being developed…”
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