Search Results - "Bruce, Annya M"
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Phase 0 trials/ Intra-Target-Microdosing (ITM) and the lung: a review
Published in BMC pulmonary medicine (29-08-2024)“…The COVID-19 pandemic has highlighted the importance of efficient drug discovery in respiratory disease. The traditional set up of clinical trials is expensive…”
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Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope
Published in European journal of nuclear medicine and molecular imaging (01-03-2021)“…Purpose The relentless rise in antimicrobial resistance is a major societal challenge and requires, as part of its solution, a better understanding of…”
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Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease
Published in BME frontiers (01-01-2021)“…There is a need to develop platforms delineating inflammatory biology of the distal human lung. We describe a platform technology approach to detect enzyme…”
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Erratum to "Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease"
Published in BME frontiers (2023)“…[This corrects the article DOI: 10.34133/2021/9834163.]…”
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An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE)
Published in American journal of respiratory and critical care medicine (15-01-2023)“…High circulating galectin-3 is associated with poor outcomes in patients with coronavirus disease (COVID-19). We hypothesized that GB0139, a potent inhaled…”
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