Search Results - "Brozmanova, M."

The role of trigeminal nasal TRPM8-expressing afferent neurons in the antitussive effects of menthol by Plevkova, J, Kollarik, M, Poliacek, I, Brozmanova, M, Surdenikova, L, Tatar, M, Mori, N, Canning, B J

“…The cold-sensitive cation channel TRPM8 is a target for menthol, which is used routinely as a cough suppressant and as an additive to tobacco and food…”
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The Prospect for Potent Sodium Voltage-Gated Channel Blockers to Relieve an Excessive Cough by Brozmanova, M, Pavelkova, N

“…An excessive, irritable, productive or non-productive coughing associated with airway inflammation belongs to pathological cough. Increased activation of…”
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The effect of stimulation and unloading of baroreceptors on cough in experimental conditions by Matloobi, A., Buday, T., Brozmanova, M., Konarska, M., Poliacek, I., Martvon, L., Plevkova, J.

“…Cough, the main airway defensive process, is modulated by multiple sensory inputs from the respiratory system and outside of it. This modulation is one of the…”
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The voltage-gated sodium channel NaV1.8 blocker A-803467 inhibits cough in the guinea pig by Brozmanova, M., Svajdova, S., Pavelkova, N., Muroi, Y., Undem, B.J., Kollarik, M.

“…•In respiratory diseases inflammation stimulates airway C-fibers to trigger cough.•Inflammatory mediators act on multiple receptors expressed in airway…”
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Regulation of Cough by Voltage-Gated Sodium Channels in Airway Sensory Nerves by Svajdova, S, Brozmanova, M.

“…Chronic cough is a significant clinical problem in many patients. Current cough suppressant therapies are largely ineffective and have many dangerous adverse…”
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Mechanisms of the adenosine A2A receptor-induced sensitization of esophageal C fibers by Brozmanova, M, Mazurova, L, Ru, F, Tatar, M, Hu, Y, Yu, S, Kollarik, M

“…Clinical studies indicate that adenosine contributes to esophageal mechanical hypersensitivity in some patients with pain originating in the esophagus. We have…”
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Vagal afferent nerves with the properties of nociceptors by Kollarik, M, Ru, F, Brozmanova, M

“…Abstract Vagal afferent nerves are essential for optimal neural regulation of visceral organs, but are not often considered important for their defense…”
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Adenosine-induced activation of esophageal nociceptors by Ru, F, Surdenikova, L, Brozmanova, M, Kollarik, M

“…Clinical studies implicate adenosine acting on esophageal nociceptive pathways in the pathogenesis of noncardiac chest pain originating from the esophagus…”
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Antitussive effects of nasal thymol challenges in healthy volunteers by Gavliakova, S, Biringerova, Z, Buday, T, Brozmanova, M, Calkovsky, V, Poliacek, I, Plevkova, J

“…Highlights ► Thymol is used empirically to reduce symptoms of respiratory diseases including cough. ► Molecular action of thymol is mediated via TRPV3 channel…”
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The effects of nasal irritant induced responses on breathing and cough in anaesthetized and conscious animal models by Biringerova, Z, Gavliakova, S, Brozmanova, M, Tatar, M, Hanuskova, E, Poliacek, I, Plevkova, J

“…Highlights • We learned very useful lessons from apnoea/hypopnoea and its role in airway defence. • Intranasal administration of AITC inhibits coughing in…”
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Preferential activation of the vagal nodose nociceptive subtype by TRPA1 agonists in the guinea pig esophagus by Brozmanova, M., Ru, F., Surdenikova, L., Mazurova, L., Taylor‐Clark, T., Kollarik, M.

“…Background  The TRPA1 receptor is directly activated by a wide range of chemicals including many endogenous molecules relevant for esophageal pathophysiology…”
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Cough reflex sensitivity is increased in the guinea pig model of allergic rhinitis by Brozmanova, M, Plevkova, J, Tatar, M, Kollarik, M

“…Increased cough reflex sensitivity is found in patients with allergic rhinitis and may contribute to cough caused by rhinitis. We have reported that cough to…”
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Modulation of experimentally-induced cough by stimulation of nasal mucosa in cats and guinea pigs by Plevkova, J., Kollarik, M., Brozmanova, M., Revallo, M., Varechova, S., Tatar, M.

“…Stimulation of afferent nerves in upper airways may contribute to the pathogenesis of chronic cough in chronic disorders of nose and/or sinuses. We tested the…”
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Distinct phenotypes of the neural crest- and placode-derived nociceptors innervating the guinea pig esophagus by Ru, F, Surdenikova, L, Brozmanova, M, Banovcin, P, Kollarik, M

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A comparison of monotherapy with lamotrigine or carbamazepine in patients with newly diagnosed partial epilepsy by Nieto-Barrera, M, Brozmanova, M, Capovilla, G, Christe, W, Pedersen, B, Kane, K, O'Neill, Fiona

“…Monotherapy with lamotrigine or carbamazepine was evaluated in a multicentre open trial of patients aged 2 years and above with newly diagnosed partial…”
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The effects of nasal histamine challenge on cough reflex in healthy volunteers by Plevkova, J., Brozmanova, M., Pecova, R., Tatar, M.

“…The aim of the study was to investigate the effects of nasal histamine on the intensity of cough reflex and the effects of intensified nasal breathing…”
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Trpa1 Receptor-Mediated Cough in the Guinea Pig by Brozmanova, M, Mazurova, L, Ru, F, Tatar, M, Kollarik, M

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Testing of cough reflex sensitivity in children suffering from allergic rhinitis and common cold by Plevkova, J, Varechova, S, Brozmanova, M, Tatar, M

“…Cough associated with upper respiratory tract disorders is a common and troublesome problem in children and little is known about the etiology of this type of…”
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Experimental allergic rhinitis-related cough and airway eosinophilia in sensitized guinea pigs by Brozmanova, M, Bartos, V, Plank, L, Tatar, M

“…Allergic rhinitis is one of the most common causes of chronic cough. The characteristic feature of allergic rhinitis is eosinophilic nasal inflammation. This…”
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Differences in oxidative status, lung function, and pulmonary surfactant during long-term inhalation of medical oxygen and partially ionized oxygen in guinea pigs by Calkovska, A, Engler, I, Mokra, D, Drgova, A, Sivonova, M, Tartarkova, Z, Calkovsky, V, Brozmanova, M, Tatar, M

“…Inhalation of partially ionized oxygen may have less adverse effects on lung functions than medical oxygen. Guinea pigs inhaled air, 100% molecular medical…”
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