Search Results - "Brownlie, R."
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A chimeric glycoprotein formulated with a combination adjuvant induces protective immunity against both human respiratory syncytial virus and parainfluenza virus type 3
Published in Antiviral research (01-10-2018)“…Human respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) are major causes of serious lower respiratory tract disease in infants. Currently…”
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Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles
Published in Vaccine (27-07-2012)“…Highlights ► CpG ODN, innate defense regulator (IDR) and polyphosphazene (PP) have adjuvant activity. ► RSV fusion protein, CpG ODN and IDR were formulated in…”
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Index coronary angiography use in Manitoba, Canada: a population-level descriptive analysis of First Nations and non-First Nations recipients
Published in BMJ open (01-03-2018)“…ObjectivesTo investigate recipient characteristics and rates of index angiography among First Nations (FN) and non-FN populations in Manitoba,…”
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Vaccination with a human parainfluenza virus type 3 chimeric FHN glycoprotein formulated with a combination adjuvant induces protective immunity
Published in Vaccine (18-12-2017)“…•Parainfluenza virus type 3 (PIV3) is a leading cause of lower respiratory disease in infants.•A chimeric PIV3 FHN protein was expressed in a HEK293T mammalian…”
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The influence of initial and post-thinning stand density on Douglas-fir branch diameter at two sites in New Zealand
Published in New Zealand journal of forestry science (02-09-2015)“…Background Branches support the foliage needed for tree growth, but if the branch diameter is too large it may constitute a defect when the tree is assessed…”
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Infection of Newborn Piglets with Bordetella pertussis: a New Model for Pertussis
Published in Infection and Immunity (01-06-2005)“…Bordetella pertussis is the causative agent of pertussis or whooping cough. This bacterium is a human pathogen that under experimental conditions also infects…”
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Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice
Published in Diabetes, obesity & metabolism (01-10-2008)“…Aim: We have generated a heterozygous glucokinase knockout mouse (gkdel/wt), upon which we investigated the effect of high‐fat diet (HFD) with respect to…”
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It's a Win-Win-Win: Using Human Peer to Peer Networks to Reach Learners Where They Are
Published in Journal of library & information services in distance learning (02-10-2018)“…In the Spring 2017 semester, an instructional designer, a writing center coordinator, and a director of distance library services initiated a pilot project for…”
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Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine
Published in Archives of virology (01-05-2006)“…Intercellular spread of bovine herpesvirus-1 (BHV-1) VP22 was demonstrated in living COS-7 cells transfected with a plasmid expressing VP22-YFP (yellow…”
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Superficial urothelial (umbrella) cells. A potential cause of abnormal DNA ploidy results in urine specimens
Published in Analytical and quantitative cytology and histology (01-10-2000)“…To determine the DNA ploidy distribution in urothelial superficial (umbrella) cells and to assess the value of the image analysis operator's experience. DNA…”
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KS01.4.A NK cells as key orchestrators in mediating the anti-tumour response to immune checkpoint blockade in melanoma brain metastases
Published in Neuro-oncology (Charlottesville, Va.) (09-09-2021)“…Abstract BACKGROUND Brain metastases (BrM) are an unmet clinical need with poor prognosis. 60% of melanoma patients develop BrM. BrM are strongly understudied…”
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P08.02 Harnessing T cells to target brain metastasis
Published in Neuro-oncology (Charlottesville, Va.) (09-09-2021)“…Abstract BACKGROUND Up to 60% of melanoma patients develop brain metastases (BrM). These patients have a poor prognosis and limited treatment options. Immune…”
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Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function
Published in Science signaling (27-11-2012)“…The cytoplasmic phosphatase PTPN22 (protein tyrosine phosphatase nonreceptor type 22) plays a key role in regulating lymphocyte homeostasis, which ensures that…”
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Differential display analysis of gene expression during the induction of mucosal immunity
Published in Immunogenetics (New York) (01-11-2000)“…One approach to understanding the physiologically relevant events during the induction of an immune response is to identify genes that are expressed when the…”
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Antibody responses in the lungs of mice following oral immunization with Salmonella typhimurium aroA and invasive Escherichia coli strains expressing the filamentous hemagglutinin of Bordetella pertussis
Published in Infection and Immunity (01-12-1991)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bordetella pertussis adenylate cyclase: purification and characterization of the toxic form of the enzyme
Published in The EMBO journal (01-09-1989)“…Bordetella pertussis produces a calmodulin‐sensitive adenylate cyclase (AC) which is an essential virulence factor in mammalian pertussis. Here we report the…”
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ZD1542, a potent thromboxane A2 synthase inhibitor and receptor antagonist in vitro
Published in British journal of pharmacology (01-12-1993)“…1 The thromboxane A2 synthase (TXS) inhibitory activity and the thromboxane A2 (TP)‐receptor blocking action of ZD1542…”
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Flow Depth in Sand-Bed Channels
Published in Journal of hydraulic engineering (New York, N.Y.) (01-07-1983)“…Six methods for predicting friction factor are evaluated and a new method is presented which better predicts flow depth (and therefore friction factor) when…”
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The relationship between blood flow and diameter in the iliac artery of the anaesthetized dog: the role of endothelium-derived relaxing factor and shear stress
Published in Experimental physiology (01-09-1994)“…The quantitative relationship between, increase in blood flow and arterial diameter was determined in an anaesthetized dog preparation (pentobarbitone,…”
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