Search Results - "Brown, Zachary D"
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A Germanium Isocyanide Complex Featuring (n → π) Back-Bonding and Its Conversion to a Hydride/Cyanide Product via C–H Bond Activation under Mild Conditions
Published in Journal of the American Chemical Society (07-03-2012)“…Reaction of the diarylgermylene Ge(ArMe6 )2 [ArMe6 = C6H3-2,6-(C6H2-2,4,6-(CH3)3)2] with tert-butyl isocyanide gave the Lewis adduct species (ArMe6 )2GeCNBu t…”
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The use of an inexpensive processing aid device (the Mouse PAD) to facilitate rodent tissue banking
Published in BioTechniques (01-07-2020)“…The generation of an experimental animal model often requires considerable investment of both time and money. Typically, investigators are interested in…”
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Mechanistic Study of Stepwise Methylisocyanide Coupling and C–H Activation Mediated by a Low-Valent Main Group Molecule
Published in Journal of the American Chemical Society (24-04-2013)“…An experimental and DFT investigation of the mechanism of the coupling of methylisocyanide and C–H activation mediated by the germylene (germanediyl) Ge(ArMe6…”
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Experimental and Computational Study of Auxiliary Molecular Effects on the Mechanism of the Addition of Hydrazines to a Low-Valent Germanium Complex
Published in Organometallics (14-05-2012)“…Reaction of the diarylgermylene Ge(ArMe6 )2 (ArMe6 = C6H3-2,6-(C6H2-2,4,6-(CH3)3)2) with hydrazine and methylhydrazine gave the first structurally…”
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5
Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure
Published in iScience (15-04-2022)“…The complex and inaccessible space radiation environment poses an unresolved risk to astronaut cardiovascular health during long-term space exploration…”
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Mechanisms of reactions of open-shell, heavier group 14 derivatives with small molecules: n-π back-bonding in isocyanide complexes, C-H activation under ambient conditions, CO coupling, and ancillary molecular interactions
Published in Inorganic chemistry (03-06-2013)“…The main themes of this review are the mechanisms of the reactions of germanium and tin analogues of carbenes with isocyanides, CO, ammonia, and related…”
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A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy
Published in Scientific reports (29-05-2019)“…Clinically, both percutaneous and surgical approaches to deliver viral vectors to the heart either have resulted in therapeutically inadequate levels of…”
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MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection
Published in Science advances (01-01-2019)“…Mast cells (MCs) are strategically distributed at barrier sites and prestore various immunocyte-recruiting cytokines, making them ideal targets for selective…”
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The Relationship Between Atrial Fibrillation, Mitral Regurgitation, and Heart Failure Subtype: The ARIC Study
Published in Journal of cardiac failure (01-06-2022)“…•Understand the interactions between heart failure, mitral regurgitation, and atrial fibrillation.•Early referral for definitive treatment of mitral valve…”
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Reversible, Photoinduced Activation of P4 by Low-Coordinate Main Group Compounds
Published in Chemistry : a European journal (26-05-2014)“…Two unique systems based on low‐coordinate main group elements that activate P4 are shown to quantitatively release the phosphorus cage upon short exposure to…”
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Facile, High-Yield Functionalization of Germanium and Tin by Oxidative Insertion of Tetrelenes into the E–H Bonds of Inorganic Acids (E = C, N, O, F): Arene Elimination versus Oxidative Addition and Formation of a Germanium Cation–Water Complex
Published in Organometallics (28-01-2013)“…Reaction of the diarylgermylene Ge(ArMe6 )2 [ArMe6 = C6H3-2,6-(C6H2-2,4,6-(CH3)3)2] with various inorganic acids (HCN, HN3, and HBF4) led to the facile…”
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12
Transition Metal Functionalization of P 4 Using a Diarylgermylene Anchor
Published in Inorganic chemistry (07-08-2017)“…The manipulation of white phosphorus (P ) has been a long-standing challenge for chemists. While the holy grail remains at finding a method to catalytically…”
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Transition Metal Functionalization of P4 Using a Diarylgermylene Anchor
Published in Inorganic chemistry (07-08-2017)“…The manipulation of white phosphorus (P4) has been a long-standing challenge for chemists. While the holy grail remains at finding a method to catalytically…”
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Mechanisms of Reactions of Open-Shell, Heavier Group 14 Derivatives with Small Molecules: n−π Back-Bonding in Isocyanide Complexes, C–H Activation under Ambient Conditions, CO Coupling, and Ancillary Molecular Interactions † This Award Article summarizes, including more recent results, one of the themes of a lecture presented on March 26th, 2012, at the 243rd Chemical Society National Meeting American in San Diego, CA, in receipt of the 2012 Award in Organometallic Chemistry sponsored by the Dow
Published in Inorganic chemistry (03-06-2013)“…The main themes of this review are the mechanisms of the reactions of germanium and tin analogues of carbenes with isocyanides, CO, ammonia, and related…”
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MOZ and MOZ-CBP cooperate with NF-κB to activate transcription from NF-κB–dependent promoters
Published in Experimental hematology (01-12-2007)“…Objective Monocytic zinc finger (MOZ) maintains hematopoietic stem cells and, upon fusion to the coactivator CREB-binding protein (CBP), induces acute myeloid…”
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Reversible, Photoinduced Activation of P 4 by Low‐Coordinate Main Group Compounds
Published in Chemistry : a European journal (26-05-2014)“…Abstract Two unique systems based on low‐coordinate main group elements that activate P 4 are shown to quantitatively release the phosphorus cage upon short…”
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Reversible, Photoinduced Activation of P sub(4) by Low-Coordinate Main Group Compounds
Published in Chemistry : a European journal (01-05-2014)“…Two unique systems based on low-coordinate main group elements that activate P sub(4) are shown to quantitatively release the phosphorus cage upon short…”
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Abstract 11970: Increasing Mitral Regurgitation Severity is Accompanied by Higher Prevalence Of Atrial Fibrillation
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionMitral regurgitation (MR) is common in patients with heart failure (HF) and is associated with atrial fibrillation (AF). The objective of this…”
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Chalcogenide/Chalcogenolate Structural Isomers of Organo Group 13 Element Derivatives: Reactions of the Dimetallenes Ar′MMAr′ (Ar′ = C 6 H 3 -2,6-(C 6 H 3 -2,6-Pr i 2 ) 2 ; M = Ga or In) with N 2 O or S 8 To Give (Ar′M III E) 2 (E = O or S) and the Synthesis and Characterization of [Ar′EM I ] 2 (M = In or Tl; E = O, S)
Published in Organometallics (27-04-2009)Get full text
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MOZ and MOZ-CBP Cooperate with NFκB To Induce Expression of NFκB-Dependent Genes
Published in Blood (16-11-2007)“…Although monocytic zinc finger protein (MOZ/MYST3) maintains normal hematopoietic stem cells, its fusion to the coactivator CREB-binding protein (CBP/CREBBP)…”
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