Search Results - "Brown, Whitney"

Effect of Recombinant Human Pentraxin 2 vs Placebo on Change in Forced Vital Capacity in Patients With Idiopathic Pulmonary Fibrosis: A Randomized Clinical Trial by Raghu, Ganesh, van den Blink, Bernt, Hamblin, Mark J, Brown, A. Whitney, Golden, Jeffrey A, Ho, Lawrence A, Wijsenbeek, Marlies S, Vasakova, Martina, Pesci, Alberto, Antin-Ozerkis, Danielle E, Meyer, Keith C, Kreuter, Michael, Santin-Janin, Hugues, Mulder, Geert-Jan, Bartholmai, Brian, Gupta, Renu, Richeldi, Luca

“…IMPORTANCE: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with poor prognosis. Approved therapies do not halt disease progression…”
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High-Flow Nasal Cannula Therapy in COVID-19: Using the ROX Index to Predict Success by Chandel, Abhimanyu, Patolia, Saloni, Brown, A Whitney, Collins, A Claire, Sahjwani, Dhwani, Khangoora, Vikramjit, Cameron, Paula C, Desai, Mehul, Kasarabada, Aditya, Kilcullen, Jack K, Nathan, Steven D, King, Christopher S

“…Optimal timing of mechanical ventilation in COVID-19 is uncertain. We sought to evaluate outcomes of delayed intubation and examine the ROX index (ie,…”
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The Value and Application of the 6-Minute-Walk Test in Idiopathic Pulmonary Fibrosis by Brown, A Whitney, Nathan, Steven D

“…The 6-minute-walk test is a commonly used assessment of performance ability in a variety of cardiopulmonary diseases. It provides important functional…”
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The Polyploid State Restricts Hepatocyte Proliferation and Liver Regeneration in Mice by Wilkinson, Patrick D., Delgado, Evan R., Alencastro, Frances, Leek, Madeleine P., Roy, Nairita, Weirich, Matthew P., Stahl, Elizabeth C., Otero, P. Anthony, Chen, Maelee I., Brown, Whitney K., Duncan, Andrew W.

“…The liver contains a mixture of hepatocytes with diploid or polyploid (tetraploid, octaploid, etc.) nuclear content. Polyploid hepatocytes are commonly found…”
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Stepping up by stepping down by Kotkowski, Christine Bielick, Brown, A. Whitney

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Outcomes of mechanically ventilated patients with COVID-19 associated respiratory failure by King, Christopher S, Sahjwani, Dhwani, Brown, A Whitney, Feroz, Saad, Cameron, Paula, Osborn, Erik, Desai, Mehul, Djurkovic, Svetolik, Kasarabada, Aditya, Hinerman, Rachel, Lantry, James, Shlobin, Oksana A, Ahmad, Kareem, Khangoora, Vikramjit, Aryal, Shambhu, Collins, A Claire, Speir, Alan, Nathan, Steven

“…The outcomes of patients requiring invasive mechanical ventilation for COVID-19 remain poorly defined. We sought to determine clinical characteristics and…”
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A Narrative Review of Emotion Regulation Abilities, Strategy Use, and Their Relationship to Alcohol by Brown, Whitney C., Melas, M. Trystan

“…Purpose of Review Poor emotion regulation (ER) abilities are associated with coping motives, alcohol use problems, and difficulties recovering from an alcohol…”
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Do Men Use More Sexually Aggressive Tactics When Intoxicated? A Within-Person Examination of Naturally Occurring Episodes of Sex by Testa, Maria, Brown, Whitney C., Wang, Weijun

“…Objective: Men's alcohol use has been linked to sexual assault perpetration. Yet, it is unknown whether within naturally occurring sexual encounters men use…”
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Do schizotypy features predict cannabis problems in partnered community adults? by Brown, Whitney C., Leonard, Kenneth, Stasiewicz, Paul R., Testa, Maria

“…•Predicted cannabis problems from schizotypal features with longitudinal methods.•Disorganized and positive schizotypy associated with cannabis use in…”
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Measuring Impulsivity in Daily Life: The Momentary Impulsivity Scale by Tomko, Rachel L., Solhan, Marika B., Carpenter, Ryan W., Brown, Whitney C., Jahng, Seungmin, Wood, Phillip K., Trull, Timothy J.

“…Impulsivity is a core feature of many psychiatric disorders. Traditionally, impulsivity has been assessed using retrospective questionnaires or laboratory…”
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Effect of Immediate Lymphatic Reconstruction on Postmastectomy Implant Reconstruction by Ahmed, Shahnur, Mercho, Patrick F., Brown, Whitney A., Aguilar Neuville, Paola, Fisher, Carla S., Lester, Mary E., Hassanein, Aladdin H.

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Impact of loss to follow-up on survival estimation for cystic fibrosis by Ostrenga, Joshua S., Whitney Brown, A., Todd, Jonathan V., Elbert, Alexander, Fink, Aliza K., Faro, Albert, Marshall, Bruce C., Cromwell, Elizabeth A.

“…Deaths among those lost to follow-up (LTFU) in the Cystic Fibrosis Foundation Patient Registry (CFFPR) are critically important to the epidemiology of cystic…”
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Cannabis and alcohol use, affect and impulsivity in psychiatric out-patients' daily lives by Trull, Timothy J., Wycoff, Andrea M., Lane, Sean P., Carpenter, Ryan W., Brown, Whitney C.

“…Background and Aims Cannabis and alcohol are the most commonly used (il)licit drugs world‐wide. We compared the effects of cannabis and alcohol use on…”
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Polyploid Hepatocytes Facilitate Adaptation and Regeneration to Chronic Liver Injury by Wilkinson, Patrick D., Alencastro, Frances, Delgado, Evan R., Leek, Madeleine P., Weirich, Matthew P., Otero, P. Anthony, Roy, Nairita, Brown, Whitney K., Oertel, Michael, Duncan, Andrew W.

“…The liver contains diploid and polyploid hepatocytes (tetraploid, octaploid, etc.), with polyploids comprising ≥90% of the hepatocyte population in adult mice…”
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Prevalence and impact of WHO group 3 pulmonary hypertension in advanced idiopathic nonspecific interstitial pneumonia by King, Christopher S, Brown, A Whitney, Shlobin, Oksana A, Weir, Nargues, Libre, Matthew, Franco-Palacios, Domingo, Ahmad, Shahzad, Nathan, Steven D

“…Pulmonary hypertension (PH) is associated with impaired quality of life, worsened functional status and increased mortality in idiopathic pulmonary fibrosis…”
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Difficulties in emotion regulation in treatment-seeking alcoholics with and without co-occurring mood and anxiety disorders by Bradizza, Clara M., Brown, Whitney C., Ruszczyk, Melanie U., Dermen, Kurt H., Lucke, Joseph F., Stasiewicz, Paul R.

“…Emotion regulation difficulties (ERD) are known to underlie mental health conditions including anxiety and depressive disorders and alcohol use disorder (AUD)…”
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Hypertonic saline has a prolonged effect on mucociliary clearance in adults with cystic fibrosis by Trimble, Aaron T., Whitney Brown, A., Laube, Beth L., Lechtzin, Noah, Zeman, Kirby L., Wu, Jihong, Ceppe, Agathe, Waltz, David, Bennett, William D., Donaldson, Scott H.

“…Inhaled hypertonic saline (HS) has been shown to increase mucociliary clearance (MCC) and improve clinical outcomes in adults and adolescents with cystic…”
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HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma by Bacigalupa, Zachary A, Arner, Emily N, Vlach, Logan M, Wolf, Melissa M, Brown, Whitney A, Krystofiak, Evan S, Ye, Xiang, Hongo, Rachel A, Landis, Madelyn, Amason, Edith K, Beckermann, Kathryn E, Rathmell, W Kimryn, Rathmell, Jeffrey C

“…Clear cell renal cell carcinoma (ccRCC) is an aggressive cancer driven by VHL loss and aberrant HIF-2α signaling. Identifying means to regulate HIF-2α thus has…”
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Long-term evaluation of the safety and efficacy of recombinant human pentraxin-2 (rhPTX-2) in patients with idiopathic pulmonary fibrosis (IPF): an open-label extension study by Raghu, Ganesh, Hamblin, Mark J, Brown, A Whitney, Golden, Jeffrey A, Ho, Lawrence A, Wijsenbeek, Marlies S, Vasakova, Martina, Pesci, Alberto, Antin-Ozerkis, Danielle E, Meyer, Keith C, Kreuter, Michael, Burgess, Tracy, Kamath, Nikhil, Donaldson, Francis, Richeldi, Luca

“…Recombinant human pentraxin-2 (rhPTX-2) significantly decreased decline in percent predicted forced vital capacity (FVC) and stabilized 6-min walk distance…”
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Idiopathic pulmonary fibrosis patients with severe physiologic impairment: characteristics and outcomes by Pastre, Jean, Barnett, Scott, Ksovreli, Inga, Taylor, Jeannie, Brown, A Whitney, Shlobin, Oksana A, Ahmad, Kareem, Khangoora, Vikramjit, Aryal, Shambhu, King, Christopher S, Nathan, Steven D

“…There is no widely accepted grading system for IPF disease severity, although physiologic impairment based on pulmonary function testing is frequently…”
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