Search Results - "Brown, Wendy C"

Adaptive immunity to Anaplasma pathogens and immune dysregulation: Implications for bacterial persistence by Brown, Wendy C

“…Abstract Anaplasma marginale is an obligate intraerythrocytic bacterium that infects ruminants, and notably causes severe economic losses in cattle worldwide…”
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Proteomics informed by transcriptomics identifies novel secreted proteins in Dermacentor andersoni saliva by Mudenda, Lwiindi, Pierlé, Sebastián Aguilar, Turse, Joshua E., Scoles, Glen A., Purvine, Samuel O., Nicora, Carrie D., Clauss, Therese R.W., Ueti, Massaro W., Brown, Wendy C., Brayton, Kelly A.

“…•Dermacentor andersoni expressed sequence tag (EST) database established from salivary gland transcripts.•Proteomics informed by transcriptomics identifies 677…”
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Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa by Brayton, Kelly A, Lau, Audrey O T, Herndon, David R, Hannick, Linda, Kappmeyer, Lowell S, Berens, Shawn J, Bidwell, Shelby L, Brown, Wendy C, Crabtree, Jonathan, Fadrosh, Doug, Feldblum, Tamara, Forberger, Heather A, Haas, Brian J, Howell, Jeanne M, Khouri, Hoda, Koo, Hean, Mann, David J, Norimine, Junzo, Paulsen, Ian T, Radune, Diana, Ren, Qinghu, Smith, Jr, Roger K, Suarez, Carlos E, White, Owen, Wortman, Jennifer R, Knowles, Jr, Donald P, McElwain, Terry F, Nene, Vishvanath M

“…Babesia bovis is an apicomplexan tick-transmitted pathogen of cattle imposing a global risk and severe constraints to livestock health and economic…”
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Persistent Infections and Immunity in Ruminants to Arthropod-Borne Bacteria in the Family Anaplasmataceae by Brown, Wendy C, Barbet, Anthony F

“…Tick-transmitted gram-negative bacteria in the family Anaplasmataceae in the order Rickettsiales cause persistent infection and morbidity and mortality in…”
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Phylogenomics Reveals a Diverse Rickettsiales Type IV Secretion System by Gillespie, Joseph J, Brayton, Kelly A, Williams, Kelly P, Quevedo Diaz, Marco A, Brown, Wendy C, Azad, Abdu F, Sobral, Bruno W

“…With an obligate intracellular lifestyle, Alphaproteobacteria of the order Rickettsiales have inextricably coevolved with their various eukaryotic hosts,…”
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Immunogenicity of Outer Membrane Proteins VirB9-1 and VirB9-2, a Novel Nanovaccine against Anaplasma marginale by Zhao, Liang, Mahony, Donna, Cavallaro, Antonino S, Zhang, Bing, Zhang, Jun, Deringer, James R, Zhao, Chun-Xia, Brown, Wendy C, Yu, Chengzhong, Mitter, Neena, Middelberg, Anton P J

“…Anaplasma marginale is the most prevalent tick-borne livestock pathogen and poses a significant threat to cattle industry. In contrast to currently available…”
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Spherical Body Protein 2 truncated copy 11 as a specific Babesia bovis attenuation marker by Gallego-Lopez, Gina M, Lau, Audrey O T, Brown, Wendy C, Johnson, Wendell C, Ueti, Massaro W, Suarez, Carlos E

“…Abstract Background Bovine babesiosis caused by Babesia bovis is a tick-borne hemoparasitic disease of global impact, and improved control is needed. In B…”
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Subdominant Outer Membrane Antigens in Anaplasma marginale: Conservation, Antigenicity, and Protective Capacity Using Recombinant Protein by Ducken, Deirdre R, Brown, Wendy C, Alperin, Debra C, Brayton, Kelly A, Reif, Kathryn E, Turse, Joshua E, Palmer, Guy H, Noh, Susan M

“…Anaplasma marginale is a tick-borne rickettsial pathogen of cattle with a worldwide distribution. Currently a safe and efficacious vaccine is unavailable…”
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Identification of Anaplasma marginale type IV secretion system effector proteins by Lockwood, Svetlana, Voth, Daniel E, Brayton, Kelly A, Beare, Paul A, Brown, Wendy C, Heinzen, Robert A, Broschat, Shira L

“…Anaplasma marginale, an obligate intracellular alphaproteobacterium in the order Rickettsiales, is a tick-borne pathogen and the leading cause of anaplasmosis…”
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Composition of the Surface Proteome of Anaplasma marginale and Its Role in Protective Immunity Induced by Outer Membrane Immunization by Noh, Susan M, Brayton, Kelly A, Brown, Wendy C, Norimine, Junzo, Munske, Gerhard R, Davitt, Christine M, Palmer, Guy H

“…Surface proteins of tick-borne, intracellular bacterial pathogens mediate functions essential for invasion and colonization. Consequently, the surface proteome…”
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Candidate Antigens for Q Fever Serodiagnosis Revealed by Immunoscreening of a Coxiella burnetii Protein Microarray by Beare, Paul A, Chen, Chen, Bouman, Timo, Pablo, Jozelyn, Unal, Berkay, Cockrell, Diane C, Brown, Wendy C, Barbian, Kent D, Porcella, Stephen F, Samuel, James E, Felgner, Philip L, Heinzen, Robert A

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Association and Evidence for Linked Recognition of Type IV Secretion System Proteins VirB9-1, VirB9-2, and VirB10 in Anaplasma marginale by Morse, Kaitlyn, Norimine, Junzo, Palmer, Guy H, Sutten, Eric L, Baszler, Timothy V, Brown, Wendy C

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Anaplasma marginale Type IV Secretion System Proteins VirB2, VirB7, VirB11, and VirD4 Are Immunogenic Components of a Protective Bacterial Membrane Vaccine by Sutten, Eric L, Norimine, Junzo, Beare, Paul A, Heinzen, Robert A, Lopez, Job E, Morse, Kaitlyn, Brayton, Kelly A, Gillespie, Joseph J, Brown, Wendy C

“…Anaplasma and related Ehrlichia spp. are important tick-borne, Gram-negative bacterial pathogens of livestock and humans that cause acute infection and disease…”
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Identification of Anaplasma marginale Outer Membrane Protein Antigens Conserved between A. marginale Sensu Stricto Strains and the Live A. marginale subsp. centrale Vaccine by Agnes, Joseph T, Brayton, Kelly A, LaFollett, Megan, Norimine, Junzo, Brown, Wendy C, Palmer, Guy H

“…Live vaccination with Anaplasma marginale subsp. centrale (synonym for Anaplasma centrale) induces protection against severe disease upon challenge with A…”
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Immunogenicity of Anaplasma marginale Type IV Secretion System Proteins in a Protective Outer Membrane Vaccine by Lopez, Job E, Palmer, Guy H, Brayton, Kelly A, Dark, Michael J, Leach, Stephanie E, Brown, Wendy C

“…Rickettsial pathogens in the genera Anaplasma and Ehrlichia cause acute infection in immunologically naive hosts and are major causes of tick-borne disease in…”
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Linkage between Anaplasma marginale Outer Membrane Proteins Enhances Immunogenicity but Is Not Required for Protection from Challenge by Noh, Susan M, Turse, Joshua E, Brown, Wendy C, Norimine, Junzo, Palmer, Guy H

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Identification of Novel Antigenic Proteins in a Complex Anaplasma marginale Outer Membrane Immunogen by Mass Spectrometry and Genomic Mapping by Lopez, Job E, Siems, William F, Palmer, Guy H, Brayton, Kelly A, McGuire, Travis C, Norimine, Junzo, Brown, Wendy C

“…Immunization with purified Anaplasma marginale outer membranes induces complete protection against infection that is associated with CD4⁺ T-lymphocyte-mediated…”
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CD4 T Cell Antigens from Staphylococcus aureus Newman Strain Identified following Immunization with Heat-Killed Bacteria by Lawrence, Paulraj K, Rokbi, Bachra, Arnaud-Barbe, Nadège, Sutten, Eric L, Norimine, Junzo, Lahmers, Kevin K, Brown, Wendy C

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Subdominant Antigens in Bacterial Vaccines: AM779 Is Subdominant in the Anaplasma marginale Outer Membrane Vaccine but Does Not Associate with Protective Immunity by Albarrak, Saleh M, Brown, Wendy C, Noh, Susan M, Reif, Kathryn E, Scoles, Glen A, Turse, Joshua E, Norimine, Junzo, Ueti, Massaro W, Palmer, Guy H, Munderloh, Ulrike Gertrud

“…Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial…”
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Anaplasma marginale Infection with Persistent High-Load Bacteremia Induces a Dysfunctional Memory CD4+ T Lymphocyte Response but Sustained High IgG Titers by Han, Sushan, Norimine, Junzo, Brayton, Kelly A, Palmer, Guy H, Scoles, Glen A, Brown, Wendy C

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