Search Results - "Brown, Thomas P."

Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption by Johnson, Kristen, Levine, Kymberly, Sergi, Joseph, Chamoun, Jean, Roach, Rachel, Vekich, Jacqueline, Favis, Mike, Horn, Mark, Cao, Xianjun, Miller, Brian, Snyder, William, Aivazian, Dikran, Reagan, William, Berryman, Edwin, Colangelo, Jennifer, Markiewicz, Victoria, Bagi, Cedo M, Brown, Thomas P, Coyle, Anthony, Mohammadi, Moosa, Magram, Jeanne

“…ABSTRACT Fibroblast growth factor 23 (FGF23) is the causative factor of X‐linked hypophosphatemia (XLH), a genetic disorder effecting 1:20,000 that is…”
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Evaluation of miR-216a and miR-217 as Potential Biomarkers of Acute Exocrine Pancreatic Toxicity in Rats by Wang, Jianying, Huang, Wenhu, Thibault, Stephane, Brown, Thomas P., Bobrowski, Walter, Gukasyan, Hovhannes J., Evering, Winston, Hu, Wenyue, John-Baptiste, Annette, Vitsky, Allison

“…Detecting and monitoring exocrine pancreatic damage during nonclinical and clinical testing is challenging because classical biomarkers amylase and lipase have…”
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Nocturnal temperature-controlled laminar airflow device for adults with severe allergic asthma: the LASER RCT by Kapoor, Melissa, Storrar, Will, Balls, Lara, Brown, Thomas P, Mansur, Adel, Hedley, Emma, Jones, Tom, Roberts, Claire, Shirkey, Beverly, Dutton, Susan, Luengo-Fernandez, Ramon, Little, Matthew, Dewey, Ann, Marshall, Sue, Fogg, Carole, Boughton, Keith, Rahman, Najib, Yu, Ly-Mee, Bradding, Peter, Howarth, Peter, Chauhan, Anoop J

“…Severe asthma exacerbations are costly to patients and the NHS, and occur frequently in severely allergic patients. To ascertain whether or not nocturnal…”
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COVID‐19: A collision of complement, coagulation and inflammatory pathways by Chauhan, Anoop J., Wiffen, Laura J., Brown, Thomas P.

“…COVID‐19 is frequently accompanied by a hypercoagulable inflammatory state with microangiopathic pulmonary changes that can precede the diffuse alveolar damage…”
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Chronic administration of an aglycosylated murine antibody of ponezumab does not worsen microhemorrhages in aged Tg2576 mice by Freeman, Gary B, Brown, Thomas P, Wallace, Karin, Bales, Kelly R

“…Cerebral vasogenic edema and microhemorrhages are potential safety concerns for compounds intended to treat subjects with Alzheimer's disease (AD) by targeting…”
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Evaluation of telehealth support in an integrated respiratory clinic by Fox, Lauren, Heiden, Emily, Chauhan, Milan A. J., Longstaff, Jayne M., Balls, Lara, De Vos, Ruth, Neville, Daniel M., Jones, Thomas L., Leung, Anthony W., Morrison, Lydia, Rupani, Hitasha, Brown, Thomas P., Stores, Rebecca, Chauhan, Anoop J.

“…Supporting self-management is key in improving disease control, with technology increasingly utilised. We hypothesised the addition of telehealth support…”
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High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy by Dower, Ken, Zhao, Shanrong, Schlerman, Franklin J, Savary, Leigh, Campanholle, Gabriela, Johnson, Bryce G, Xi, Li, Nguyen, Vuong, Zhan, Yutian, Lech, Matthew P, Wang, Ju, Nie, Qing, Karsdal, Morten A, Genovese, Federica, Boucher, Germaine, Brown, Thomas P, Zhang, Baohong, Homer, Bruce L, Martinez, Robert V

“…ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high…”
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COVID-19 vaccine hesitancy in a developing country: prevalence, explanatory factors and implications for the future by Wynter-Adams, D., Thomas-Brown, P.

“…Vaccine hesitancy is a public health challenge highlighted during the COVID-19 pandemic. This study sought to determine the prevalence and explanatory factors…”
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A systematic review of methods of scoring inhaler technique by De Vos, Ruth, Hicks, Alexander, Lomax, Mitch, Mackenzie, Heather, Fox, Lauren, Brown, Thomas P, Chauhan, A J

“…Many inhaler devices are currently used in clinical practice to deliver medication, with each inhaler device offering different benefits to overcome technique…”
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IL-21 Has a Pathogenic Role in a Lupus-Prone Mouse Model and Its Blockade with IL-21R.Fc Reduces Disease Progression by Herber, Deborah, Brown, Thomas P, Liang, Spencer, Young, Deborah A, Collins, Mary, Dunussi-Joannopoulos, Kyri

“…Systemic lupus erythematosus is a complex autoimmune disease characterized by dysregulated interactions between autoreactive T and B lymphocytes and the…”
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Pure autonomic failure by Brown, Thomas P

“…Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to…”
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Polyomavirus-associated Prostatitis in Wistar Han Rats Following Immunosuppression in a Chronic Toxicity Study by Masek-Hammerman, Katherine, Brown, Thomas P., Bobrowski, Walter F., Tomlinson, Lindsay, Debrue, Marie, Whiteley, Laurence, Radi, Zaher

“…Chronic prostatitis characterized on light microscopic examination by moderate, multifocal, predominantly lymphocytic inflammation associated with epithelial…”
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Attenuation, Safety, and Efficacy of an Infectious Bronchitis Virus GA98 Serotype Vaccine by Jackwood, Mark W, Hilt, Deborah A, Brown, Thomas P

“…In 1998, novel strains of infectious bronchitis virus (IBV) were identified in chickens from the southeastern United States and classified as a new serotype…”
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Mild Infectious Laryngotracheitis in Broilers in the Southeast by Sellers, Holly S, García, Maricarmen, Glisson, John R, Brown, Thomas P, Sander, Jean S, Guy, James S

“…During 2001, a mild infectious laryngotracheitis virus (ILTV) infection occurred in broiler flocks in the southeastern United States. Clinical signs included…”
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"UNFAIR" PRACTICES IN THE FINANCIAL SERVICES INDUSTRY: THE NEW BOSS IS THE SAME AS THE OLD BOSS by Brown, Thomas P., Lee, Dae Ho

“…On August 24, 2015, the Third Circuit made headlines with its decision in FTC v. Wyndham Worldwide Corp.1 The decision sustained the Federal Trade Commission's…”
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PAEs AND ANTITRUST—A BRIEF INTRODUCTION by Brown, Thomas P.

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Toxicopathology of the Developing Immune System: Investigative and Development Strategies by Weinstock, Daniel, Lewis, David B., Parker, George A., Beyer, Joseph, Collinge, Mark, Brown, Thomas P., Dybdal, Noel

“…Developmental immunotoxicity (DIT) has gained attention with the recognition that environmental chemicals can potentially affect the developing immune system…”
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The effects of cyclophosphamide treatment on the pathogenesis of subgroup J avian leukosis virus (ALV-J) infection in broiler chickens with Marek`s disease virus exposure by Kim, Yongbaek, Brown, Thomas P, Pantin-Jackwood, Mary J

“…Studies were performed to determine the effects of Bcell suppression on the pathogenesis of Subgroup J avian leukosis virus (ALV-J) in broiler chickens…”
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Using the Inflammacheck Device to Measure the Level of Exhaled Breath Condensate Hydrogen Peroxide in Patients With Asthma and Chronic Obstructive Pulmonary Disease (The EXHALE Pilot Study): Protocol for a Cross-Sectional Feasibility Study by Neville, Daniel M, Fogg, Carole, Brown, Thomas P, Jones, Thomas L, Lanning, Eleanor, Bassett, Paul, Chauhan, Anoop J

“…Asthma and Chronic Obstructive Pulmonary Disease (COPD) are common conditions that affect over 5 million people in the United Kingdom. These groups of patients…”
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Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek’s disease virus exposure by Kim, Yongbaek, Brown, Thomas P, Pantin-Jackwood, Mary J

“…In this study, we investigated the effects of T-cell suppression on the pathogenesis of subgroup J avian leukosis virus (ALV-J). Chickens were treated with…”
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