Search Results - "Brown, Rebecca S.H."
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Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation
Published in The Journal of biological chemistry (29-04-2016)“…Torsin ATPases are the only representatives of the AAA+ ATPase family that reside in the lumen of the endoplasmic reticulum (ER) and nuclear envelope. Two of…”
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A designed repeat protein as an affinity capture reagent
Published in Biochemical Society transactions (01-10-2015)“…Repeat proteins are an attractive target for protein engineering and design. We have focused our attention on the design and engineering of one particular…”
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Torsins: not your typical AAA+ ATPases
Published in Critical reviews in biochemistry and molecular biology (02-11-2015)“…Torsin ATPases (Torsins) belong to the widespread AAA+ (ATPases associated with a variety of cellular activities) family of ATPases, which share structural…”
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mechanism of Torsin ATPase activation
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2014)“…Significance Torsin activity critically depends on accessory cofactors that activate their ATPase activity by a poorly understood mechanism. This study…”
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Regulation of Torsin ATPases by LAP1 and LULL1
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2013)“…TorsinA is a membrane-associated AAA+ (ATPases associated with a variety of cellular activities) ATPase implicated in primary dystonia, an autosomal-dominant…”
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The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1
Published in Journal of virology (01-08-2015)“…TorsinA is a membrane-tethered AAA+ ATPase implicated in nuclear envelope dynamics as well as the nuclear egress of herpes simplex virus 1 (HSV-1). The…”
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Comprehensive Investigation of MicroRNAs Enhanced by Analysis of Sequence Variants, Expression Patterns, ARGONAUTE Loading, and Target Cleavage
Published in Plant physiology (Bethesda) (01-07-2013)“…MicroRNAs (miRNAs) are a class of small RNAs that typically function by guiding the cleavage of target messenger RNAs. They have been shown to play major roles…”
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Comprehensive Investigation of MicroRNAs Enhanced by Analysis of Sequence Variants, Expression Patterns, ARGONAUTE Loading, and Target Cleavage1[W][OA]
Published in Plant physiology (Bethesda) (24-05-2013)“…A combinatorial approach of small RNA expression analysis with ARGONAUTE immunoprecipitation data and global cleavage data of RNA ends leads to a global…”
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