Search Results - "Brown, Randall H."
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Model-based transcriptome engineering promotes a fermentative transcriptional state in yeast
Published in Proceedings of the National Academy of Sciences - PNAS (22-11-2016)“…The ability to rationally manipulate the transcriptional states of cells would be of great use in medicine and bioengineering. We have developed an algorithm,…”
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Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner
Published in Bioinformatics (01-07-2009)“…Motivation: The most accurate way to determine the intron–exon structures in a genome is to align spliced cDNA sequences to the genome. Thus, cDNA-to-genome…”
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Begin at the beginning: predicting genes with 5' UTRs
Published in Genome research (01-05-2005)“…The retrainable, comparative gene predictor N-SCAN integrates multigenome modeling and 5' untranslated region (5' UTR) modeling. In this article, we evaluate…”
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Gene prediction and verification in a compact genome with numerous small introns
Published in Genome research (01-11-2004)“…The genomes of clusters of related eukaryotes are now being sequenced at an increasing rate, creating a need for accurate, low-cost annotation of exon-intron…”
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Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment
Published in Genome biology (01-01-2006)“…This study analyzes the predictions of a number of promoter predictors on the ENCODE regions of the human genome as part of the ENCODE Genome Annotation…”
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Critical evaluation of low-order moment expansions for the bonding energy of lattices and defects
Published in Physical review. B, Condensed matter (15-11-1985)“…An exact evaluation of the cohesive energy E sub coh in a large number of model defect and bulk systems is used to assess the accuracy of truncated moment…”
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Pairagon+N-SCAN_EST: a model-based gene annotation pipeline
Published in Genome biology (01-01-2006)“…This paper describes Pairagon+N-SCAN_EST, a gene annotation pipeline that uses only native alignments. For each expressed sequence it chooses the best genomic…”
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Calculation of the electronic properties of Ni-P amorphous alloys
Published in Physical review. B, Condensed matter (1993)“…The atomic structure of Ni--P amorphous alloys were simulated for several concentrations (Ni sub 75 P sub 25 , Ni sub 80 P sub 20 , and Ni sub 85 P sub 15 ),…”
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