Search Results - "Brown, Oscar A."

Rejuvenation by cell reprogramming: a new horizon in gerontology by Goya, Rodolfo G, Lehmann, Marianne, Chiavellini, Priscila, Canatelli-Mallat, Martina, Hereñú, Claudia B, Brown, Oscar A

“…The discovery of animal cloning and subsequent development of cell reprogramming technology were quantum leaps as they led to the achievement of rejuvenation…”
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The Thymus-Neuroendocrine Axis by Reggiani, Paula C., Morel, Gustavo R., Cónsole, Gloria M., Barbeito, Claudio G., Rodriguez, Silvia S., Brown, Oscar A., Bellini, Maria Jose, Pléau, Jean-Marie, Dardenne, Mireille, Goya, Rodolfo G.

“…Thymulin is a thymic hormone exclusively produced by the thymic epithelial cells. It consists of a nonapeptide component coupled to the ion zinc, which confers…”
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Rejuvenating Effect of Long-Term Insulin-Like Growth Factor-I Gene Therapy in the Hypothalamus of Aged Rats with Dopaminergic Dysfunction by Schwerdt, José I, Lopez-Leon, Micaela, Cónsole, Gloria M, Brown, Oscar A, Morel, Gustavo R, Spinedi, Eduardo, Goya, Rodolfo G

“…The aging female rat constitutes an interesting model of spontaneous and progressive age-related dopaminergic dysfunction as it allows assessing new…”
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The thymus-neuroendocrine axis: physiology, molecular biology, and therapeutic potential of the thymic peptide thymulin by Reggiani, Paula C, Morel, Gustavo R, Cónsole, Gloria M, Barbeito, Claudio G, Rodriguez, Silvia S, Brown, Oscar A, Bellini, Maria Jose, Pléau, Jean-Marie, Dardenne, Mireille, Goya, Rodolfo G

“…Thymulin is a thymic hormone exclusively produced by the thymic epithelial cells. It consists of a nonapeptide component coupled to the ion zinc, which confers…”
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The thymulin-lactotropic axis in rodents: thymectomy, immunoneutralization and gene transfer studies by Martines, Eliana V, Reggiani, Paula C, Camihort, Gisela, Luna, Georgina, Zappa, Maria F, Brown, Oscar A, Goya, Rodolfo G, Cónsole, Gloria M

“…There is clear evidence on the existence of a thymus-pituitary axis which seems to be particularly important during perinatal life. In particular, the thymic…”
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Peripheral and mesencephalic transfer of a synthetic gene for the thymic peptide thymulin by Morel, Gustavo R., Brown, Oscar A., Reggiani, Paula C., Hereñú, Claudia B., Portiansky, Enrique L., Zuccolilli, Gustavo O., Pléau, Jean M., Dardenne, Mireille, Goya, Rodolfo G.

“…Thymulin is a thymic peptide with antiinflammatory activity in the brain. We constructed a recombinant adenoviral vector, RAd-FTS, expressing a synthetic DNA…”
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Thymulin and the neuroendocrine system by Goya, Rodolfo G., Brown, Oscar A., Pléau, Jean-Marie, Dardenne, Mireille

“…Thymulin is a thymic hormone exclusively produced by the thymic epithelial cells. It consists of a nonapeptide component coupled to the ion zinc, which confers…”
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Potential of gene therapy for restoration of endocrine thymic function in thymus-deficient animal models by Morel, Gustavo R, Reggiani, Paula C, Console, Gloria M, Rimoldi, Omar J, Vesenbeckh, Silvan M, Garcia-Bravo, Margarita M, Rodriguez, Silvia S, Brown, Oscar A, Goya, Rodolfo G

“…The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic…”
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Studies on in vivo gene transfer in pituitary tumors using herpes-derived and adenoviral vectors by Carri, Néstor G., Sosa, Yolanda E., Brown, Oscar A., Albariño, César, Romanowski, Víctor, Goya, Rodolfo G.

“…Suicide gene therapy has met limited success for the treatment of rat pituitary tumors. In order to determine the cause of primary pituitary tumor resistance…”
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The neuroendocrine system as a model to evaluate experimental gene therapy by Hereñú, Claudia B, Brown, Oscar A, Sosa, Yolanda E, Morel, Gustavo R, Reggiani, Paula C, Bellini, Maria J, Goya, Rodolfo G

“…The implementation of experimental gene therapy in animal models of neurological diseases is an area of growing interest. Although the neuroendocrine system…”
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Studies on the gonadotropin-releasing activity of thymulin: changes with age by Brown, O A, Sosa, Y E, Dardenne, M, Pléau, J M, Goya, R G

“…We assessed the ability of thymulin, a zinc-dependent nonapeptide produced by the thymic epithelial cells, to influence the release of luteinizing hormone (LH)…”
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Thymus and aging: potential of gene therapy for restoration of endocrine thymic function in thymus-deficient animal models by Goya, Rodolfo G, Cónsole, Gloria M, Hereñú, Claudia B, Brown, Oscar A, Rimoldi, Omar J

“…The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states…”
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Hypophysotropic activity of histone H3 in vitro by Brown, Oscar A., Sosa, Yolanda E., Naumovich, Diana, Hereñú, Claudia B., Goya, Rodolfo G.

“…To assess the effect of histone H3 on pituitary hormone secretion, rat anterior pituitary (AP) cells were used and growth hormone, prolactin, thyrotropin,…”
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Growth hormone-releasing activity of thymulin on pituitary somatotropes is age dependent by Brown, O A, Sosa, Y E, Dardenne, M, Pléau, J, Goya, R G

“…Thymulin is a Zn-bound nonapeptide produced by the thymic epithelial cells (TEC) whose secretion is modulated by growth hormone (GH), among others. We assessed…”
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Thymulin stimulates prolactin and thyrotropin release in an age-related manner by Brown, Oscar A, Sosa, Yolanda E, Bolognani, Federico, Goya, Rodolfo G

“…Thymulin is a Zn-bound nonapeptide produced by the thymic epithelial cells (TEC) whose secretion is modulated by prolactin (PRL) and thyroid hormones, among…”
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Thyrotropin-Releasing Activity of Histone H2A, H2B and Peptide MB35 by Brown, Oscar A, Sosa, Yolanda E, Goya, Rodolfo G

“…Brown, O. A., Y. E. Sosa and R. G. Goya. Thyrotropin-releasing activity of histones H2A, H2B and peptide MB35. Peptides 18(9) 1315–1319, 1997.—Histones possess…”
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Hypophysiotropic activity of histone H3 in vitro by Brown, Oscar A, Sosa, Yolanda E, Naumovich, Diana, Hereñú, Claudia B, Goya, Rodolfo G

“…To assess the effect of histone H3 on pituitary hormone secretion, rat anterior pituitary (AP) cells were used and growth hormone, prolactin, thyrotropin,…”
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The thymus-pituitary axis and its changes during aging by Goya, R G, Brown, O A, Bolognani, F

“…The pituitary-thymic axis constitutes a bidirectional circuit where the ascending feedback loop is effected by thymic factors of epithelial origin. The aim of…”
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Hormonal modulation of antioxidant enzyme activities in young and old rats by Bolzán, Alejandro D., Brown, Oscar A., Goya, Rodolfo G., Bianchi, Martha S.

“…The correlation between serum levels of pituitary and thyroid hormones and the activity of two antioxidant enzymes (AOE), catalase (CAT) and superoxide…”
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Studies on the prolactin-releasing mechanism of histones H2A and H2B by Brown, Oscar A., Sosa, Yolanda E., Castro, Maria G., Goya, Rodolfo G.

“…In previous studies we demonstrated that histone preparations possess multiple effects in vivo on pituitary hormone secretion. We have now studied the…”
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