Search Results - "Brown, Nigel L"

Cysteine coordination of Pb(II) is involved in the PbrR-dependent activation of the lead-resistance promoter, PpbrA, from Cupriavidus metallidurans CH34 by Hobman, Jon L, Julian, Daniel J, Brown, Nigel L

“…The pbr resistance operon from Cupriavidus metallidurans CH34 plasmid pMOL30 confers resistance to Pb(II) salts, and is regulated by the Pb(II) responsive…”
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Sequence and Analysis of a Plasmid-Encoded Mercury Resistance Operon from Mycobacterium marinum Identifies MerH, a New Mercuric Ion Transporter by SCHUE, Mathieu, DOVER, Lynn G, BESRA, Gurdyal. S, PARKHILL, Julian, BROWN, Nigel L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Biosensors for detection of mercury in contaminated soils by Bontidean, Ibolya, Mortari, Alessia, Leth, Suzanne, Brown, Nigel L., Karlson, Ulrich, Larsen, Martin M., Vangronsveld, Jaco, Corbisier, Philippe, Csöregi, Elisabeth

“…Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil…”
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Climate factors influencing bacterial count in background air samples by Harrison, Roy M, Jones, Alan M, Biggins, Peter D E, Pomeroy, Nigel, Cox, Christopher S, Kidd, Stephen P, Hobman, Jon L, Brown, Nigel L, Beswick, Alan

“…Total (as opposed to culturable) bacterial number counts are reported for four sites in the United Kingdom measured during campaigns over four separate…”
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The Pco proteins are involved in periplasmic copper handling in Escherichia coli by Lee, Sun Mi, Grass, Gregor, Rensing, Christopher, Barrett, Siobhán R, Yates, Christopher J.D, Stoyanov, Jivko V, Brown, Nigel L

“…The interactions between the plasmid-borne copper resistance determinant, pco, and the main copper export system in Escherichia coli have been investigated and…”
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Detection of Heavy Metal Ions at Femtomolar Levels Using Protein-Based Biosensors by Bontidean, Ibolya, Berggren, Christine, Johansson, Gillis, Csöregi, Elisabeth, Mattiasson, Bo, Lloyd, Jonathan R, Jakeman, Kenneth J, Brown, Nigel L

“…Sensors based on proteins (GST-SmtA and MerR) with distinct binding sites for heavy metal ions were developed and characterized. A capacitive signal transducer…”
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Protein-Based Capacitive Biosensors: a New Tool for Structure-Activity Relationship Studies by Mortari, Alessia, Campos-Reales, Natalhie, Corda, Giulia, Brown, Nigel L., Csöregi, Elisabeth

“…The present work reports a new application of a protein‐based capacitive biosensor as an in vitro assay for the selectivity study of the bacterial periplasmic…”
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The MerR family of transcriptional regulators by Brown, Nigel L, Stoyanov, Jivko V, Kidd, Stephen P, Hobman, Jon L

“…The MerR family is a group of transcriptional activators with similar N-terminal helix-turn-helix DNA binding regions and C-terminal effector binding regions…”
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Mercury Resistance Determinants Related to Tn21, Tn1696, and Tn5053 in Enterobacteria from the Preantibiotic Era by ESSA, Ashraf M. M, JULIAN, Daniel J, KIDD, Stephen P, BROWN, Nigel L, HOBMAN, Jon L

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The expression profile of Escherichia coli K-12 in response to minimal, optimal and excess copper concentrations by Kershaw, Christopher J, Brown, Nigel L, Constantinidou, Chrystala, Patel, Mala D, Hobman, Jon L

“…School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK Correspondence Jon L. Hobman J.L.Hobman{at}bham.ac.uk The gene…”
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Zinc dependence of zinT ( yodA) mutants and binding of zinc, cadmium and mercury by ZinT by Kershaw, Christopher J., Brown, Nigel L., Hobman, Jon L.

“…ZinT (B1973), previously known as YodA, was originally characterised as a cadmium-induced periplasmic protein under the regulation of Fur and SoxS. Here we…”
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A design for life: prokaryotic metal-binding MerR family regulators by Hobman, Jon L, Wilkie, John, Brown, Nigel L

“…The MerR family of metal-binding, metal-responsive proteins is unique in that they activate transcription from unusual promoters and coordinate metals through…”
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CueR (YbbI) of Escherichia coli is a MerR family regulator controlling expression of the copper exporter CopA by Stoyanov, Jivko V., Hobman, Jon L., Brown, Nigel L.

“…We have shown that the open reading frame ybbI in the genomic sequence of Escherichia coli K‐12 encodes the regulator of expression of the copper‐exporting…”
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Transcriptional activation of MerR family promoters in Cupriavidus metallidurans CH34 by Julian, Daniel J, Kershaw, Christopher J, Brown, Nigel L, Hobman, Jon L

“…Metal responsive MerR family transcriptional regulators are widespread in bacteria and activate the transcription of genes involved in metal ion…”
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Whole cell- and protein-based biosensors for the detection of bioavailable heavy metals in environmental samples by Corbisier, Philippe, van der Lelie, Daniel, Borremans, Brigitte, Provoost, Ann, de Lorenzo, Victor, Brown, Nigel L, Lloyd, Jonathan R, Hobman, Jonathan L, Csöregi, Elisabeth, Johansson, Gillis, Mattiasson, Bo

“…The principal goal of this work was to establish the feasibility of two biosensor technologies with enhanced specificity and selectivity for the detection of…”
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ZntR is a Zn(II)‐responsive MerR‐like transcriptional regulator of zntA in Escherichia coli by Brocklehurst, Kathryn R., Hobman, Jon L., Lawley, Blair, Blank, Lindsay, Marshall, Samantha J., Brown, Nigel L., Morby, Andrew P.

“…We have identified the promoter/operator region of the zntA gene of Escherichia coli and shown that Zn(II) is the primary inducer of expression of this…”
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Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501 mer operon by Schue, Mathieu, Glendinning, Kerry J, Hobman, Jon L, Brown, Nigel L

“…Mercuric ion resistance in bacteria requires transport of mercuric ions (Hg²⁺) into the cytoplasmic compartment where they are reduced to the less toxic…”
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Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501mer operon by Schue, Mathieu, Glendinning, Kerry J., Hobman, Jon L., Brown, Nigel L.

“…Mercuric ion resistance in bacteria requires transport of mercuric ions (Hg 2+ ) into the cytoplasmic compartment where they are reduced to the less toxic…”
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multicopper oxidase (CueO) and cell aggregation in Escherichia coli by Tree, Jai J, Ulett, Glenn C, Hobman, Jon L, Constantinidou, Chrystala, Brown, Nigel L, Kershaw, Christopher, Schembri, Mark A, Jennings, Michael P, McEwan, Alastair G

“…cueO encodes a periplasmic multicopper oxidase, which is known to be involved in copper homeostasis and protection against oxidative stress in Escherichia coli…”
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Molecular genetics and transport analysis of the copper-resistance determinant (pco) from Escherichia coli plasmid pRJ1004 by Brown, N L, Barrett, S R, Camakaris, J, Lee, B T, Rouch, D A

“…The copper-resistance determinant (pco) of Escherichia coli plasmid pRJ1004 was cloned and sequenced. Tn1000 transposon mutagenesis identified four…”
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