Search Results - "Brown, Myles A"
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p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases
Published in Nature communications (18-03-2022)“…Approximately 50% of patients with metastatic HER2-positive (HER2+) breast cancer develop brain metastases (BCBMs). We report that the tumor suppressor p16…”
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Journal Article -
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Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Published in Nature medicine (01-10-2018)“…Cancer treatment by immune checkpoint blockade (ICB) can bring long-lasting clinical benefits, but only a fraction of patients respond to treatment. To predict…”
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Journal Article -
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Target-Directed Enediynes: Designed Estramycins
Published in Journal of organic chemistry (01-06-2001)“…The goal of selective targeting of enediyne cytotoxins has been investigated using estrogenic delivery vehicles. A series of estrogen−enediyne conjugates were…”
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Overview consensus statement
Published in Urology (Ridgewood, N.J.) (01-09-2002)Get full text
Journal Article -
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Abstract 4759: Dissecting EP300 and CBP function in prostate cancer models
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Prostate adenocarcincoma is dependent on androgen and its cellular receptor the androgen receptor (AR) for most of the natural history of the disease…”
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Journal Article -
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Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
Published in Clinical cancer research (01-01-2004)Get full text
Journal Article Conference Proceeding -
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Protein-Degrading Enediynes: Library Screening of Bergman Cycloaromatization Products
Published in Organic letters (29-06-2000)“…A screening method based on Bergman cycloaromatization products was applied to a compact library of estrogenic-enediyne hybrids. An enediyne candidate…”
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Journal Article -
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Abstract 3376: Reprogramming the estrogen signaling network is a potential mechanism for human breast tumorigenesis
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Background: The estrogen receptor (ER) is expressed in approximately 70% of sporadic breast cancers and is known to activate genes driving cell…”
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Journal Article -
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The Adoption of Conservation Practices and Program Participation Among Socially Disadvantaged Agricultural Producers: A Meta-Analysis
Published 01-01-2022“…As climate change has become undeniable in recent years, it has become increasingly important for the agriculture industry to address conservation. Within the…”
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Dissertation -
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p16 INK4A -deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases
Published in Nature communications (18-03-2022)“…Approximately 50% of patients with metastatic HER2-positive (HER2+) breast cancer develop brain metastases (BCBMs). We report that the tumor suppressor p16 is…”
Get full text
Journal Article -
11
Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer
Published in Clinical cancer research (01-01-2004)Get full text
Journal Article -
12
Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer
Published in Urology (Ridgewood, N.J.) (01-09-2002)Get full text
Journal Article