Search Results - "Brown, Matthew T"

Dichotomous Organization of the External Globus Pallidus by Mallet, Nicolas, Micklem, Benjamin R., Henny, Pablo, Brown, Matthew T., Williams, Claire, Bolam, J. Paul, Nakamura, Kouichi C., Magill, Peter J.

“…Different striatal projection neurons are the origin of a dual organization essential for basal ganglia function. We have defined an analogous division of…”
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Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning by Brown, Matthew T. C., Tan, Kelly R., O’Connor, Eoin C., Nikonenko, Irina, Muller, Dominique, Lüscher, Christian

“…GABA-releasing neurons from the ventral tegmental area that project to the nucleus accumbens are shown to block the firing of cholinergic accumbal…”
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Simple procedure for an estimation of the coal rank using micro-Raman spectroscopy by Hinrichs, Ruth, Brown, Matthew T., Vasconcellos, Marcos A.Z., Abrashev, Miroslav V., Kalkreuth, Wolfgang

“…An alternative way for an estimation of coal rank, based on micro-Raman spectroscopy, is presented. Raman spectra and mean random reflectance percentage (%Rr)…”
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Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients by Ousterout, David G, Perez-Pinera, Pablo, Thakore, Pratiksha I, Kabadi, Ami M, Brown, Matthew T, Qin, Xiaoxia, Fedrigo, Olivier, Mouly, Vincent, Tremblay, Jacques P, Gersbach, Charles A

“…Genome editing with engineered nucleases has recently emerged as an approach to correct genetic mutations by enhancing homologous recombination with a DNA…”
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Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases by Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Perez-Pinera, Pablo, Brown, Matthew T, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A

“…Duchenne muscular dystrophy (DMD) is caused by genetic mutations that result in the absence of dystrophin protein expression. Oligonucleotide-induced exon…”
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Training in Implementation Practice Leadership (TRIPLE): evaluation of a novel practice change strategy in behavioral health organizations by Proctor, Enola, Ramsey, Alex T, Brown, Matthew T, Malone, Sara, Hooley, Cole, McKay, Virginia

“…Effective leadership for organizational change is critical to the implementation of evidence-based practices (EBPs). As organizational leaders in behavioral…”
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Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation by Brown, Matthew T C, Bellone, Camilla, Mameli, Manuel, Labouèbe, Gwenael, Bocklisch, Christina, Balland, Bénédicte, Dahan, Lionel, Luján, Rafael, Deisseroth, Karl, Lüscher, Christian

“…Addictive drugs have in common that they cause surges in dopamine (DA) concentration in the mesolimbic reward system and elicit synaptic plasticity in DA…”
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Morphological and Biophysical Determinants of the Intracellular and Extracellular Waveforms in Nigral Dopaminergic Neurons: A Computational Study by López-Jury, Luciana, Meza, Rodrigo C, Brown, Matthew T C, Henny, Pablo, Canavier, Carmen C

“…Action potentials (APs) in nigral dopaminergic neurons often exhibit two separate components: the first reflecting spike initiation in the dendritically…”
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Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases by Perez-Pinera, Pablo, Ousterout, David G, Brown, Matthew T, Gersbach, Charles A

“…Targeted gene addition to mammalian genomes is central to biotechnology, basic research and gene therapy. For example, gene targeting to the ROSA26 locus by…”
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Activity of Neurochemically Heterogeneous Dopaminergic Neurons in the Substantia Nigra during Spontaneous and Driven Changes in Brain State by Brown, Matthew T. C, Henny, Pablo, Bolam, J. Paul, Magill, Peter J

“…Dopaminergic neurons of the substantia nigra (SN) and ventral tegmental area (VTA) are collectively implicated in motor- and reward-related behaviors. However,…”
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Building capacity for dissemination and implementation research: one university's experience by Brownson, Ross C, Proctor, Enola K, Luke, Douglas A, Baumann, Ana A, Staub, Mackenzie, Brown, Matthew T, Johnson, Mallory

“…While dissemination and implementation (D&I) science has grown rapidly, there is an ongoing need to understand how to build and sustain capacity in individuals…”
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Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area by Lüscher, Christian, Mameli, Manuel, Bellone, Camilla, Brown, Matthew T C

“…The manner in which drug-evoked synaptic plasticity affects reward circuits remains largely elusive. We found that cocaine reduced NMDA receptor excitatory…”
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Redefining the Roles of Aspirin across the Spectrum of Cardiovascular Disease Prevention by Brown, Matthew T, Bortfeld, Kristina S, Sperling, Laurence S, Wenger, Nanette K

“…Even before its role in platelet inhibition was fully characterized in the 1980s, aspirin had been incorporated into the cardiovascular disease care algorithm…”
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Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes by Fine, Eli J., Appleton, Caleb M., White, Douglas E., Brown, Matthew T., Deshmukh, Harshavardhan, Kemp, Melissa L., Bao, Gang

“…CRISPR/Cas9 systems have been used in a wide variety of biological studies; however, the large size of CRISPR/Cas9 presents challenges in packaging it within…”
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Stereological and ultrastructural quantification of the afferent synaptome of individual neurons by Henny, Pablo, Brown, Matthew T. C., Micklem, Benjamin R., Magill, Peter J., Bolam, J. Paul

“…Determining the number and placement of synaptic inputs along the distinct plasma membrane domains of neurons is essential for explaining the basis of neuronal…”
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Trace metal distributions within a Sitka eddy in the northern Gulf of Alaska by Brown, Matthew T., Lippiatt, Sherry M., Lohan, Maeve C., Bruland, Kenneth W.

“…In the northern Gulf of Alaska, mesoscale, anticyclonic eddies have been implicated as a mechanism of the cross-shelf exchange of iron (Fe)-replete coastal…”
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A commercially available rosette system for trace metal—clean sampling by Measures, Christopher I., Landing, William M., Brown, Matthew T., Buck, Clifton S.

“…To obtain trace element data sets of sufficient resolution to resolve and interpret biogeochemical features, it is necessary to develop sampling schemes that…”
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Same-Day Versus Next-Day Discharge Strategies for Left Atrial Ablation Procedures: A Parallel, Intra-Institutional Comparison of Safety and Feasibility by T Brown, Matthew, M Pelling, Mary, Kiani, Soroosh, M Merchant, Faisal, F El-Chami, Mikhael, R Leon, Angel, Westerman, Stacy, Shah, Anand, Wise, Donna, S Lloyd, Michael

“…Head-to-head comparative data for the postoperative care of patients undergoing left atrial ablation procedures are lacking. We sought to investigate…”
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Reactive iron delivery to the Gulf of Alaska via a Kenai eddy by Lippiatt, Sherry M., Brown, Matthew T., Lohan, Maeve C., Bruland, Kenneth W.

“…Mesoscale anticyclonic eddies in the Gulf of Alaska are an important mechanism for cross-shelf exchange of high iron, low nitrate coastal waters and low iron,…”
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Postoperative video debriefing reduces technical errors in laparoscopic surgery by Hamad, Giselle G., M.D., F.A.C.S, Brown, Matthew T., Ph.D, Clavijo-Alvarez, Julio A., M.D., Ph.D

“…Abstract Background Because of the learning curve required to master laparoscopic procedures, there is a growing concern that patient safety may be compromised…”
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