Search Results - "Brown, M. C."

RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway by Gonsalves, Foster C, Klein, Keren, Carson, Brittany B, Katz, Shauna, Ekas, Laura A, Evans, Steve, Nagourney, Robert, Cardozo, Timothy, Brown, Anthony M.C, DasGupta, Ramanuj

“…Misregulated β-catenin responsive transcription (CRT) has been implicated in the genesis of various malignancies, including colorectal carcinomas, and it is a…”
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Photosymbiosis reduces the environmental stress response under a heat challenge in a facultatively symbiotic coral by Wuitchik, D. M., Aichelman, H. E., Atherton, K. F., Brown, C. M., Chen, X., DiRoberts, L., Pelose, G. E., Tramonte, C. A., Davies, S. W.

“…The symbiosis between corals and dinoflagellates of the family Symbiodiniaceae is sensitive to environmental stress. The oxidative bleaching hypothesis posits…”
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Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres by Many, Alexander M, Brown, Anthony M C

“…The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the…”
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Supportive oncology care at home interventions: protocols for clinical trials to shift the paradigm of care for patients with cancer by Nipp, Ryan D, Shulman, Eliza, Smith, Melissa, Brown, Patricia M C, Johnson, P Connor, Gaufberg, Eva, Vyas, Charu, Qian, Carolyn L, Neckermann, Isabel, Hornstein, Shira B, Reynolds, Mathew J, Greer, Joseph, Temel, Jennifer S, El-Jawahri, Areej

“…Patients with cancer often endure substantial symptoms and treatment toxicities leading to high healthcare utilization, including hospitalizations and…”
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Evaluating new paralysis, mortality, and readmission among subgroups of patients with spinal epidural abscess: A latent class analysis by Brown, Patrick C. M, Phillipi, Gina M, King, Caroline, Tanski, Mary, Sullivan, Peter

“…Background Spinal epidural abscess (SEA) is increasing in incidence; this not-to-miss diagnosis can cause significant morbidity and mortality, particularly if…”
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Calibration approaches for distributed hydrologic models in poorly gaged basins: implication for streamflow projections under climate change by Wi, S, Yang, Y. C. E, Steinschneider, S, Khalil, A, Brown, C. M

“…This study tests the performance and uncertainty of calibration strategies for a spatially distributed hydrologic model in order to improve model simulation…”
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Simulating the Impact of the Natural Radiation Background on Bacterial Systems: Implications for Very Low Radiation Biological Experiments by Lampe, Nathanael, Biron, David G, Brown, Jeremy M C, Incerti, Sébastien, Marin, Pierre, Maigne, Lydia, Sarramia, David, Seznec, Hervé, Breton, Vincent

“…At very low radiation dose rates, the effects of energy depositions in cells by ionizing radiation is best understood stochastically, as ionizing particles…”
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Role of Ovarian Hormones in the Modulation of Sleep in Females Across the Adult Lifespan by Brown, Alana M C, Gervais, Nicole J

“…Abstract Ovarian hormones, including 17β-estradiol, are implicated in numerous physiological processes, including sleep. Beginning at puberty, girls report…”
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Pressure-induced shift of effective Ce valence, Fermi energy and phase boundaries in CeOs4Sb12 by Götze, K, Pearce, M J, Coak, M J, Goddard, P A, Grockowiak, A D, Coniglio, W A, Tozer, S W, Graf, D E, Maple, M B, Ho, P-C, Brown, M C, Singleton, J

“…CeOs4Sb12, a member of the skutterudite family, has an unusual semimetallic low-temperature L-phase that inhabits a wedge-like area of the field H—temperature…”
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Geant4‐DNA example applications for track structure simulations in liquid water: A report from the Geant4‐DNA Project by Incerti, S., Kyriakou, I., Bernal, M. A., Bordage, M. C., Francis, Z., Guatelli, S., Ivanchenko, V., Karamitros, M., Lampe, N., Lee, S. B., Meylan, S., Min, C. H., Shin, W. G., Nieminen, P., Sakata, D., Tang, N., Villagrasa, C., Tran, H. N., Brown, J. M. C.

“…This Special Report presents a description of Geant4‐DNA user applications dedicated to the simulation of track structures (TS) in liquid water and associated…”
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Time-to-completed-imaging, survival and function in patients with spinal epidural abscess: Description of a series of 34 patients, 2015-2018 by King, Caroline, Fisher, Cameron, Brown, Patrick C M, Priest, Kelsey C, Tanski, Mary, Sullivan, Peter

“…Spinal epidural abscess (SEA) is a rare and life-threatening infection with increasing incidence over the past two decades. Delays in diagnosis can cause…”
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Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I by Dass, Randall A, Sarshad, Aishe A, Carson, Brittany B, Feenstra, Jennifer M, Kaur, Amanpreet, Obrdlik, Ales, Parks, Matthew M, Prakash, Varsha, Love, Damon K, Pietras, Kristian, Serra, Rosa, Blanchard, Scott C, Percipalle, Piergiorgio, Brown, Anthony M C, Vincent, C Theresa

“…Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor…”
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Systems-based accident analysis in the led outdoor activity domain: application and evaluation of a risk management framework by Salmon, P., Williamson, A., Lenné, M., Mitsopoulos-Rubens, E., Rudin-Brown, C.M.

“…Safety-compromising accidents occur regularly in the led outdoor activity domain. Formal accident analysis is an accepted means of understanding such events…”
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Novel Powder-Supported Size-Selected Clusters for Heterogeneous Catalysis under Realistic Reaction Conditions by Habibpour, V, Song, M. Y, Wang, Z. W, Cookson, J, Brown, C. M, Bishop, P. T, Palmer, R. E

“…Well-defined nanoparticles show promise as model catalysts in the quest for new/improved practical catalysts with tunable chemical properties. Here we…”
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Nonthermal Velocities in Solar Active Regions Observed with the Extreme-Ultraviolet Imaging Spectrometer on Hinode by Doschek, G. A, Mariska, J. T, Warren, H. P, Brown, C. M, Culhane, J. L, Hara, H, Watanabe, T, Young, P. R, Mason, H. E

“…We discuss nonthermal velocities in an active region as revealed by the Extreme-Ultraviolet Imaging Spectrometer (EIS) on the Hinode spacecraft. The velocities…”
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Police officer in-vehicle discomfort: Appointments carriage method and vehicle seat features by Filtness, A.J., Mitsopoulos-Rubens, E., Rudin-Brown, C.M.

“…Musculoskeletal pain is commonly reported by police officers. A potential cause of officer discomfort is a mismatch between vehicle seats and the method used…”
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A local effect model-based interpolation framework for experimental nanoparticle radiosensitisation data by Brown, Jeremy M. C., Currell, Fred J.

“…A local effect model (LEM)-based framework capable of interpolating nanoparticle-enhanced photon-irradiated clonogenic cell survival fraction measurements as a…”
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The long-term psychosocial impact of cancer: the views of young adult survivors of childhood cancer by Brown, M.C., Pearce, M.S., Bailey, S., Skinner, R.

“…It is rare for studies to approach psychosocial outcomes of childhood cancer in a holistic and explanatory way. Doing so would enable a greater understanding…”
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NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma by Zhao, S, Kurenbekova, L, Gao, Y, Roos, A, Creighton, C J, Rao, P, Hicks, J, Man, T-K, Lau, C, Brown, A M C, Jones, S N, Lazar, A J, Ingram, D, Lev, D, Donehower, L A, Yustein, J T

“…Osteosarcoma (OS) is the most frequent pediatric malignant bone tumor that has a high propensity for metastases. Through osteoblast-specific alteration of p53…”
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Four score years and ten An analysis of the epidemiology of fractures in the very elderly by COURT-BROWN, C. M, CLEMENT, N

“…Fragility fractures are becoming more common and with increasing longevity it seems likely that orthopaedic surgeons will see more such fractures in…”
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