Search Results - "Brown, M Anthony"

RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway by Gonsalves, Foster C, Klein, Keren, Carson, Brittany B, Katz, Shauna, Ekas, Laura A, Evans, Steve, Nagourney, Robert, Cardozo, Timothy, Brown, Anthony M.C, DasGupta, Ramanuj

“…Misregulated β-catenin responsive transcription (CRT) has been implicated in the genesis of various malignancies, including colorectal carcinomas, and it is a…”
Get full text

Gamma-rays from SS433: evidence for periodicity by Rasul, Kajwan, Chadwick, Paula M, Graham, Jamie A, Brown, Anthony M

“…ABSTRACT In this paper we present our study of the gamma-ray emission from the microquasar SS433. Integrating over 9 yr of Fermi-LAT Pass 8 data, we detect…”
Get full text

Gamma-ray emission from high Galactic latitude globular clusters by Lloyd, Sheridan J, Chadwick, Paula M, Brown, Anthony M

Get full text

A search for Centaurus A-like features in the spectra of Fermi-LAT detected radio galaxies by Rulten, Cameron B, Brown, Anthony M, Chadwick, Paula M

“…ABSTRACT Motivated by the detection of a hardening in the γ-ray spectrum of the radio galaxy Centaurus A, we have analysed $\mathord {\sim }10$ yr of…”
Get full text

Both canonical and non-canonical Wnt signaling independently promote stem cell growth in mammospheres by Many, Alexander M, Brown, Anthony M C

“…The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the…”
Get full text

Fermi-LAT observations of extreme spectral variability in IC 310 by Graham, Jamie A, Brown, Anthony M, Chadwick, Paula M

“…Abstract We investigate the physical mechanisms of high-energy gamma-ray emission from the TeV-emitting misaligned active galactic nucleus IC 310. 8 yr of data…”
Get full text

Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion by Losa, Marta, Risolino, Maurizio, Li, Bingsi, Hart, James, Quintana, Laura, Grishina, Irina, Yang, Hui, Choi, Irene F, Lewicki, Patrick, Khan, Sameer, Aho, Robert, Feenstra, Jennifer, Vincent, C Theresa, Brown, Anthony M C, Ferretti, Elisabetta, Williams, Trevor, Selleri, Licia

“…Human cleft lip with or without cleft palate (CL/P) is a common craniofacial abnormality caused by impaired fusion of the facial prominences. We have…”
Get full text

Antibiotic use for Vibrio infections: important insights from surveillance data by Wong, Kam Cheong, Brown, Anthony M, Luscombe, Georgina M, Wong, Shin Jie, Mendis, Kumara

“…There is a paucity of data on the in vivo efficacy of antibiotics for lethal Vibrio species. Analyses of long-term surveillance datasets may provide insights…”
Get full text

Lensing in the Blue. II. Estimating the Sensitivity of Stratospheric Balloons to Weak Gravitational Lensing by McCleary, Jacqueline E., Everett, Spencer W., Shaaban, Mohamed M., Gill, Ajay S., Vassilakis, Georgios N., Huff, Eric M., Massey, Richard J., Benton, Steven J., Brown, Anthony M., Clark, Paul, Holder, Bradley, Fraisse, Aurelien A., Jauzac, Mathilde, Jones, William C., Lagattuta, David, Leung, Jason S.-Y., Li, Lun, T. Luu, Thuy Vy, Nagy, Johanna M., Netterfield, C. Barth, Paracha, Emaad, Redmond, Susan F., Rhodes, Jason D., Schmoll, Jürgen, Sirks, Ellen, Tam, Sut Ieng

“…Abstract The Superpressure Balloon-borne Imaging Telescope ( SuperBIT ) is a diffraction-limited, wide-field, 0.5 m, near-infrared to near-ultraviolet…”
Get full text

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I by Dass, Randall A, Sarshad, Aishe A, Carson, Brittany B, Feenstra, Jennifer M, Kaur, Amanpreet, Obrdlik, Ales, Parks, Matthew M, Prakash, Varsha, Love, Damon K, Pietras, Kristian, Serra, Rosa, Blanchard, Scott C, Percipalle, Piergiorgio, Brown, Anthony M C, Vincent, C Theresa

“…Ribosome biogenesis is essential for cell growth and proliferation and is commonly elevated in cancer. Accordingly, numerous oncogene and tumor suppressor…”
Get full text

Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells by Stadler, Sonja C, Vincent, C Theresa, Fedorov, Victor D, Patsialou, Antonia, Cherrington, Brian D, Wakshlag, Joseph J, Mohanan, Sunish, Zee, Barry M, Zhang, Xuesen, Garcia, Benjamin A, Condeelis, John S, Brown, Anthony M C, Coonrod, Scott A, Allis, C David

“…Peptidylarginine deiminase 4 (PAD4) is a Ca ²⁺-dependent enzyme that converts arginine and methylarginine residues to citrulline, with histone proteins being…”
Get full text

Locating the gamma-ray emission region in the brightest Fermi-LAT flat-spectrum radio quasars by Acharyya, Atreya, Chadwick, Paula M, Brown, Anthony M

“…ABSTRACT We present a temporal and spectral analysis of the gamma-ray flux from nine of the brightest flat-spectrum radio quasars (FSRQs) detected with the…”
Get full text

Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir by Santiago, Francisco, Oguma, Junya, Brown, Anthony M.C., Laurence, Jeffrey

“…► First demonstration of direct role for noncanonical Wnt in osteoclast differentiation. ► Demonstration of Ryk as a Wnt5a/b receptor in inhibition of…”
Get full text

High-energy γ-ray properties of the Fanaroff-Riley type I radio galaxy NGC 1275 by Brown, Anthony M., Adams, Jenni

“…We report on our study of the high-energy γ-ray emission from the Fanaroff-Riley type I (FR I) radio galaxy NGC 1275, based on 2 yr of observations with the…”
Get full text

The effect of pulsar geometry on the observed gamma-ray spectrum of millisecond pulsars by Lloyd, Sheridan J, Chadwick, Paula M, Brown, Anthony M

“…ABSTRACT We analyse 13 yr of Fermi Large Area Telescope Pass 8 events from 127 gamma-ray emitting millisecond pulsars (MSPs) in the energy range 0.1–100 GeV…”
Get full text

Wnt Proteins Induce Dishevelled Phosphorylation via an LRP5/6- Independent Mechanism, Irrespective of Their Ability To Stabilize β-Catenin by González-Sancho, José M, Brennan, Keith R, Castelo-Soccio, Leslie A, Brown, Anthony M C

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Localizing the γ-ray emission region during the 2014 June outburst of 3C 454.3 by Coogan, Rosemary T., Brown, Anthony M., Chadwick, Paula M.

“…In 2014 May–July, the flat spectrum radio quasar 3C 454.3 exhibited strong flaring behaviour. Observations with the Large Area Telescope detector on-board the…”
Get full text

Haploinsufficiency of Flap Endonuclease (Fen1) Leads to Rapid Tumor Progression by Kucherlapati, Melanie, Yang, Kan, Kuraguchi, Mari, Zhao, Jie, Lia, Maria, Heyer, Joerg, Kane, Michael F., Fan, Kunhua, Russell, Robert, Anthony M. C. Brown, Kneitz, Burkhard, Edelmann, Winfried, Kolodner, Richard D., Lipkin, Martin, Kucherlapati, Raju

“…Flap endonuclease (Fen1) is required for DNA replication and repair, and defects in the gene encoding Fen1 cause increased accumulation of mutations and genome…”
Get full text

Wnt signalling regulates myogenic differentiation in the developing avian wing by Anakwe, Kelly, Robson, Lesley, Hadley, Julia, Buxton, Paul, Church, Vicki, Allen, Steve, Hartmann, Christine, Harfe, Brian, Nohno, Tsutomu, Brown, Anthony M C, Evans, Darrell J R, Francis-West, Philippa

“…The limb musculature arises by delamination of premyogenic cells from the lateral dermomyotome. Initially the cells express Pax3 but, upon entering the limb…”
Get full text

Gamma-ray novae: rare or nearby? by Morris, Paul J, Cotter, Garret, Brown, Anthony M, Chadwick, Paula M

“…Classical novae were revealed as a surprise source of ...-rays in Fermi Large Area Telescope (LAT) observations. During the first 8 yr since the LAT was…”
Get full text