Search Results - "Brown, Kim H"

Comparative Analysis of the Shared Sex-Determination Region (SDR) among Salmonid Fishes by Faber-Hammond, Joshua J, Phillips, Ruth B, Brown, Kim H

“…Salmonids present an excellent model for studying evolution of young sex-chromosomes. Within the genus, Oncorhynchus, at least six independent sex-chromosome…”
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Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis by Brown, Kim H, Dobrinski, Kimberly P, Lee, Arthur S, Gokcumen, Omer, Mills, Ryan E, Shi, Xinghua, Chong, Wilson W. S, Chen, Jin Yun Helen, Yoo, Paulo, David, Sthuthi, Peterson, Samuel M, Raj, Towfique, Choy, Kwong Wai, Stranger, Barbara E, Williamson, Robin E, Zon, Leonard I, Freeman, Jennifer L, Lee, Charles

“…Copy number variants (CNVs) represent a substantial source of genomic variation in vertebrates and have been associated with numerous human diseases. Despite…”
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Author Correction: Assembly and Analysis of Unmapped Genome Sequence Reads Reveal Novel Sequence and Variation in Dogs by Holden, Lindsay A., Arumilli, Meharji, Hytönen, Marjo K., Hundi, Sruthi, Salojärvi, Jarkko, Brown, Kim H., Lohi, Hannes

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma by Chen, Eleanor Y, Dobrinski, Kimberly P, Brown, Kim H, Clagg, Ryan, Edelman, Elena, Ignatius, Myron S, Chen, Jin Yun Helen, Brockmann, Jillian, Nielsen, G Petur, Ramaswamy, Sridhar, Keller, Charles, Lee, Charles, Langenau, David M

“…Human cancer genomes are highly complex, making it challenging to identify specific drivers of cancer growth, progression, and tumor maintenance. To bypass…”
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Aneuploid sperm formation in rainbow trout exposed to the environmental estrogen 17α-ethynylestradiol by Brown, Kim H, Schultz, Irvin R, Cloud, J.G, Nagler, James J

“…Environmental contaminants that mimic native estrogens (i.e., environmental estrogens) are known to significantly impact a wide range of vertebrate species and…”
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Reduced embryonic survival in rainbow trout resulting from paternal exposure to the environmental estrogen 17α-ethynylestradiol during late sexual maturation by Brown, Kim H, Schultz, Irvin R, Nagler, James J

“…Exposure of fishes to environmental estrogens is known to affect sexual development and spawning, but little information exists regarding effects on gametes…”
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Baseline mRNA expression differs widely between common laboratory strains of zebrafish by Holden, Lindsay A., Brown, Kim H.

“…Common strains of wildtype zebrafish ( Danio rerio ) have unique genomic features including SNPs and CNV, but strain information often goes unreported in the…”
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Anchored pseudo-de novo assembly of human genomes identifies extensive sequence variation from unmapped sequence reads by Faber-Hammond, Joshua J., Brown, Kim H.

“…The human genome reference (HGR) completion marked the genomics era beginning, yet despite its utility universal application is limited by the small number of…”
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Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies by Frazer, J. Kimble, Batchelor, Lance A., Bradley, Diana F., Brown, Kim H., Dobrinski, Kimberly P., Lee, Charles, Trede, Nikolaus S.

“…Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In…”
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Assembly and Analysis of Unmapped Genome Sequence Reads Reveal Novel Sequence and Variation in Dogs by Holden, Lindsay A., Arumilli, Meharji, Hytönen, Marjo K., Hundi, Sruthi, Salojärvi, Jarkko, Brown, Kim H., Lohi, Hannes

“…Dogs are excellent animal models for human disease. They have extensive veterinary histories, pedigrees, and a unique genetic system due to breeding practices…”
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Pseudo-De Novo Assembly and Analysis of Unmapped Genome Sequence Reads in Wild Zebrafish Reveal Novel Gene Content by Faber-Hammond, Joshua J, Brown, Kim H

“…Zebrafish represents the third vertebrate with an officially completed genome, yet it remains incomplete with additions and corrections continuing with the…”
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An Interrogation of Shared and Unique Copy Number Variants Across Genetically Distinct Zebrafish Strains by Holden, Lindsay A, Wilson, Charles, Heineman, Zachary, Dobrinski, Kimberly P, Brown, Kim H

“…Zebrafish (Danio rerio) are a widely utilized model system for human disorders, but common laboratory strains have distinct behavioral and physiological…”
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Mitochondrial and nuclear inheritance in an androgenetic line of rainbow trout, Oncorhynchus mykiss by Brown, Kim H., Thorgaard, Gary H.

“…Mitochondrial and nuclear inheritance of clonal rainbow trout produced by androgenesis were evaluated using DNA sequencing and amplified fragment length…”
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Lack of a heritable reproductive defect in the offspring of male rainbow trout exposed to the environmental estrogen 17α-ethynylestradiol by Brown, Kim H., Schultz, Irvin R., Nagler, James J.

“…Endocrine disruptors, including environmental estrogens, have been shown to induce heritable effects through both genetic and epigenetic mechanisms in mammals…”
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Molecular Cytogenetic Methodologies and a BAC Probe Panel Resource for Genomic Analyses in the Zebrafish by Dobrinski, Kimberly P., Brown, Kim H., Freeman, Jennifer L., Lee, Charles

“…Molecular cytogenetics is a field that emerged in the 1980s, based on a technique referred to as fluorescence in situ hybridization, (FISH). Using FISH…”
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Genetic analysis of a development rate QTL in backcrosses of clonal rainbow trout, Oncorhynchus mykiss by Sundin, Kyle, Brown, Kim H., Drew, Robert E., Nichols, Krista M., Wheeler, Paul A., Thorgaard, Gary H.

“…Backcrosses of clonal rainbow trout, Oncorhynchus mykiss, were used in an effort for fine-mapping of a quantitative trait locus (QTL) for rapid embryonic…”
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Effect of parental exposure to trenbolone and the brominated flame retardant BDE-47 on fertility in rainbow trout ( Oncorhynchus mykiss) by Schultz, Irv, Brown, Kim H., Nagler, James J.

“…We exposed sexually maturing male rainbow trout ( Oncorhynchus mykiss) to BDE-47 (a polybrominated diphenyl ether) and female rainbow trout to trenbolone (an…”
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Intraspecific variation in the rainbow trout mitochondrial DNA genome by Brown, Kim H., Drew, Robert E., Weber, Lee A., Thorgaard, Gary H.

“…Four complete mitochondrial DNA genomes for rainbow trout, Oncorhynchus mykiss, were sequenced and compared to the previously reported complete mitochondrial…”
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Genetic Analysis of Interior Pacific Northwest Oncorhynchus mykiss Reveals Apparent Ancient Hybridization with Westslope Cutthroat Trout by Brown, Kim H., Patton, Steve J., Martin, Kyle E., Nichols, Krista M., Armstrong, Robyn, Thorgaard, Gary H.

“…Seventeen populations of Oncorhynchus mykiss were analyzed for mitochondrial haplotype diversity through either polymerase chain reaction–restriction fragment…”
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Nomenclature of Mitochondrial DNA Haplotypes for Oncorhynchus mykiss by Graziano, Sara L., Brown, Kim H., Nielsen, Jennifer L.

“…Congruence of genetic data is critical for comparative and collaborative studies on natural fish populations. A comprehensive list of reported mitochrondrial…”
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