Search Results - "Brown, Karen L."

Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen by McCulloch, Laura, Brown, Karen L, Bradford, Barry M, Hopkins, John, Bailey, Mick, Rajewsky, Klaus, Manson, Jean C, Mabbott, Neil A

“…Prion diseases are characterised by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein (PrP(C)), in affected tissues…”
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The Effects of Host Age on the Transport of Complement-Bound Complexes to the Spleen and the Pathogenesis of Intravenous Scrapie Infection by BROWN, Karen L, GOSSNER, Anton, MOK, Simon, MABBOTT, Neil A

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A Teacher's Guide to Flexible Grouping and Collaborative Learning: Form, Manage, Assess, and Differentiate in Groups by Brulles, Dina, Brown, Karen L

“…Grouping learners purposefully throughout the school day based on their needs and the curriculum remains the single best way to differentiate instruction. This…”
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Alterations in junctional proteins, inflammatory mediators and extracellular matrix molecules in eosinophilic esophagitis by Abdulnour-Nakhoul, Solange M, Al-Tawil, Youhanna, Gyftopoulos, Alex A, Brown, Karen L, Hansen, Molly, Butcher, Kathy F, Eidelwein, Alexandra P, Noel, Robert A, Rabon, Edd, Posta, Allison, Nakhoul, Nazih L

“…Abstract Eosinophilic esophagitis (EoE), an inflammatory atopic disease of the esophagus, causes massive eosinophil infiltration, basal cell hyperplasia, and…”
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The Effects of Host Age on Follicular Dendritic Cell Status Dramatically Impair Scrapie Agent Neuroinvasion in Aged Mice by Brown, Karen L, Wathne, Gwennaelle J, Sales, Jill, Bruce, Moira E, Mabbott, Neil A

“…Following peripheral exposure, many transmissible spongiform encephalopathy (TSE) agents accumulate first in lymphoid tissues before spreading to the CNS…”
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JOURNAL CLUB: Scatter Radiation Dose From Digital Screening Mammography Measured in a Representative Patient Population by Chetlen, Alison L, Brown, Karen L, King, Steven H, Kasales, Claudia J, Schetter, Susann E, Mack, Julie A, Zhu, Junjia

“…The purpose of this study was to quantify the amount of scatter radiation received at the skin surface overlying the thyroid gland, salivary gland, lens of the…”
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Glycosylation of PrPC Determines Timing of Neuroinvasion and Targeting in the Brain following Transmissible Spongiform Encephalopathy Infection by a Peripheral Route by CANCELLOTTI, Enrico, BRADFORD, Barry M, TUZI, Nadia L, HICKEY, Raymond D, BROWN, Debbie, BROWN, Karen L, BARRON, Rona M, KISIELEWSKI, Dorothy, PICCARDO, Pedro, MANSON, Jean C

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Sites of prion protein accumulation in scrapie-infected mouse spleen revealed by immuno-electron microscopy by Jeffrey, Martin, McGovern, Gillian, Goodsir, Caroline M., L Brown, Karen, Bruce, Moira E.

“…Prion protein (PrP) from the brains of animals with transmissible spongiform encephalopathies is partially protease resistant (PrPres) compared with fully…”
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Calcium-sensing receptor deletion in the mouse esophagus alters barrier function by Nakhoul, Nazih L, Tu, Chia-Ling, Brown, Karen L, Islam, M Toriqul, Hodges, Anna G, Abdulnour-Nakhoul, Solange M

“…Calcium-sensing receptor (CaSR) is the molecular sensor by which cells respond to small changes in extracellular Ca concentrations. CaSR has been reported to…”
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Evidence of subclinical prion disease in aged mice following exposure to bovine spongiform encephalopathy by Brown, Karen L, Mabbott, Neil A

“…The occurrence of variant Creutzfeldt-Jakob (vCJD) disease in humans was almost certainly the result of consumption of food contaminated with bovine spongiform…”
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Collaborative Partnership: The Practical Elements by Brown, Karen L.

“…Establishing a collaborative partnership takes a willingness to see the benefits despite the obstacles. Understanding how the partnership will impact each of…”
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Genetic Variants in Patients With a Family History of Pancreatic Cancer: Impact of Multigene Panel Testing by Zhu, Huili, Welinsky, Sara, Soper, Emily R., Brown, Karen L., Abul-Husn, Noura S., Lucas, Aimee L.

“…Up to 15% of pancreatic cancer is hereditary. We aim to study the prevalence of pathogenic germline variants (PGVs) in patients referred for genetic counseling…”
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Prion pathogenesis is unaltered following down-regulation of SIGN-R1 by Bradford, Barry M, Brown, Karen L, Mabbott, Neil A

“…Abstract Prion diseases are infectious neurodegenerative disorders characterised by accumulations of abnormal prion glycoprotein in affected tissues. Following…”
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Decision-making about genetic testing among women at familial risk for breast cancer by Jacobsen, P B, Valdimarsdottier, H B, Brown, K L, Offit, K

“…Recent identification of the breast-ovarian cancer susceptibility gene BRCA1 and the breast cancer susceptibility gene BRCA2 have raised the possibility of…”
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Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues by Mohan, Joanne, Brown, Karen L, Farquhar, Christine F, Bruce, Moira E, Mabbott, Neil A

“…Background : Transmissible spongiform encephalopathies (TSEs) are chronic infectious neurodegenerative diseases that are characterized by the accumulation in…”
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Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function by McCulloch, Laura, Brown, Karen L., Mabbott, Neil A.

“…Summary Follicular dendritic cells (FDC) are situated in the primary follicles of lymphoid tissues where they maintain the structural integrity of the…”
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Co-Care: A Registry for Individuals at Increased Risk for Colorectal Cancer by Sperling, Dylan, Jandorf, Lina, Sriphanlop, Pathu, Martinez, Clarissa, Brown, Karen L, Soper, Emily R, Hiraki, Susan, Itzkowitz, Steven H

“…INTRODUCTION: Colorectal cancer (CRC) is one of the leading causes of cancer death for both men and women in the United States. Several factors can increase…”
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Teacher Support Is Just a Click Away! Creating an Interactive Resource Site for Today's Teachers by Brulles, Dina, Brown, Karen L.

“…This article describes one school district department's efforts to train and support teachers in providing effective curriculum, instruction, and assessment…”
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Cytoskeletal changes induced by allosteric modulators of calcium‐sensing receptor in esophageal epithelial cells by Abdulnour‐Nakhoul, Solange, Brown, Karen L., Rabon, Edd C., Al‐Tawil, Youhanna, Islam, Mohammed T., Schmieg, John J., Nakhoul, Nazih L.

“…The calcium‐sensing receptor (CaSR), a G‐protein‐coupled receptor, plays a role in glandular and fluid secretion in the gastrointestinal tract, and regulates…”
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M1954 A Telomerase-Immortalized, Non-Neoplastic, Human Barrett's Cell Line As Model of Ion Transport and Barrier Function of Native Barrett's Specialized Columnar Epithelium by Jovov, Biljana, Orlando, Geraldine S, Brown, Karen L, Orlando, Roy C

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