Search Results - "Brown, Julia M."

Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial by Greenwood, John P, Dr, Maredia, Neil, MBChB, Younger, John F, MBChB, Brown, Julia M, Prof, Nixon, Jane, Prof, Everett, Colin C, MSc, Bijsterveld, Petra, MA, Ridgway, John P, PhD, Radjenovic, Aleksandra, PhD, Dickinson, Catherine J, PhD, Ball, Stephen G, Prof, Plein, Sven, PhD

“…Summary Background In patients with suspected coronary heart disease, single-photon emission computed tomography (SPECT) is the most widely used test for the…”
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Major role of nitrite-oxidizing bacteria in dark ocean carbon fixation by Pachiadaki, Maria G., Sintes, Eva, Bergauer, Kristin, Brown, Julia M., Record, Nicholas R., Swan, Brandon K., Mathyer, Mary Elizabeth, Hallam, Steven J., Lopez-Garcia, Purificacion, Takaki, Yoshihiro, Nunoura, Takuro, Woyke, Tanja, Herndl, Gerhard J., Stepanauskas, Ramunas

“…Carbon fixation by chemoautotrophic microorganisms in the dark ocean has a major impact on global carbon cycling and ecological relationships in the ocean’s…”
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Charting the Complexity of the Marine Microbiome through Single-Cell Genomics by Pachiadaki, Maria G., Brown, Julia M., Brown, Joseph, Bezuidt, Oliver, Berube, Paul M., Biller, Steven J., Poulton, Nicole J., Burkart, Michael D., La Clair, James J., Chisholm, Sallie W., Stepanauskas, Ramunas

“…Marine bacteria and archaea play key roles in global biogeochemistry. To improve our understanding of this complex microbiome, we employed single-cell genomics…”
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The Incidence of Low Anterior Resection Syndrome as Assessed in an International Randomized Controlled Trial (MRC/NIHR ROLARR) by Bolton, William S., Chapman, Stephen J., Corrigan, Neil, Croft, Julie, Collinson, Fiona, Brown, Julia M., Jayne, David G.

“…OBJECTIVE:To investigate the incidence of LARS in patients undergoing elective anterior resection within the MRC/NIHR ROLARR trial and to explore perioperative…”
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Resolving the structure of phage–bacteria interactions in the context of natural diversity by Kauffman, Kathryn M., Chang, William K., Brown, Julia M., Hussain, Fatima A., Yang, Joy, Polz, Martin F., Kelly, Libusha

“…Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages) and bacteria are interacting is a major challenge in the context of…”
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Evidence-Based Guidelines for Determination of Sample Size and Interpretation of the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 by COCKS, Kim, KING, Madeleine T, VELIKOVA, Galina, MARTYN ST-JAMES, Marrissa, FAYERS, Peter M, BROWN, Julia M

“…PURPOSE; To use published literature to estimate large, medium, and small differences in quality of life (QOL) data from the European Organisation for the…”
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Improved genome recovery and integrated cell-size analyses of individual uncultured microbial cells and viral particles by Stepanauskas, Ramunas, Fergusson, Elizabeth A., Brown, Joseph, Poulton, Nicole J., Tupper, Ben, Labonté, Jessica M., Becraft, Eric D., Brown, Julia M., Pachiadaki, Maria G., Povilaitis, Tadas, Thompson, Brian P., Mascena, Corianna J., Bellows, Wendy K., Lubys, Arvydas

“…Microbial single-cell genomics can be used to provide insights into the metabolic potential, interactions, and evolution of uncultured microorganisms. Here we…”
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Randomized Trial of Laparoscopic-Assisted Resection of Colorectal Carcinoma: 3-Year Results of the UK MRC CLASICC Trial Group by JAYNE, David G, GUILLOU, Pierre J, THORPE, Helen, QUIRKE, Philip, COPELAND, Joanne, SMITH, Adrian M. H, HEATH, Richard M, BROWN, Julia M

“…The aim of the current study is to report the long-term outcomes after laparoscopic-assisted surgery compared with conventional open surgery within the context…”
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The Impact of Postoperative Complications on Long-term Quality of Life After Curative Colorectal Cancer Surgery by Brown, Sarah R, Mathew, Ronnie, Keding, Ada, Marshall, Helen C, Brown, Julia M, Jayne, David G

“…OBJECTIVE:To investigate the effect that complications have on patientsʼ long-term quality of life (QoL) after curative colorectal cancer surgery…”
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Impact of Pressure Ulcers on Quality of Life in Older Patients: A Systematic Review by Gorecki, Claudia, Brown, Julia M., Nelson, E. Andrea, Briggs, Michelle, Schoonhoven, Lisette, Dealey, Carol, Defloor, Tom, Nixon, Jane

“…OBJECTIVES: To identify the impact of pressure ulcers (PUs) and PU interventions on health‐related quality of life (HRQL). DESIGN: Systematic review and…”
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Decoupling of respiration rates and abundance in marine prokaryoplankton by Munson-McGee, Jacob H., Lindsay, Melody R., Sintes, Eva, Brown, Julia M., D’Angelo, Timothy, Brown, Joe, Lubelczyk, Laura C., Tomko, Paxton, Emerson, David, Orcutt, Beth N., Poulton, Nicole J., Herndl, Gerhard J., Stepanauskas, Ramunas

“…The ocean–atmosphere exchange of CO 2 largely depends on the balance between marine microbial photosynthesis and respiration. Despite vast taxonomic and…”
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Rokubacteria: Genomic Giants among the Uncultured Bacterial Phyla by Becraft, Eric D, Woyke, Tanja, Jarett, Jessica, Ivanova, Natalia, Godoy-Vitorino, Filipa, Poulton, Nicole, Brown, Julia M, Brown, Joseph, Lau, M C Y, Onstott, Tullis, Eisen, Jonathan A, Moser, Duane, Stepanauskas, Ramunas

“…Recent advances in single-cell genomic and metagenomic techniques have facilitated the discovery of numerous previously unknown, deep branches of the tree of…”
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The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis by Morgan, Gareth J., Gregory, Walter M., Davies, Faith E., Bell, Sue E., Szubert, Alexander J., Brown, Julia M., Coy, Nuria N., Cook, Gordon, Russell, Nigel H., Rudin, Claudius, Roddie, Huw, Drayson, Mark T., Owen, Roger G., Ross, Fiona M., Jackson, Graham H., Child, J. Anthony

“…Thalidomide maintenance has the potential to modulate residual multiple myeloma (MM) after an initial response. This trial compared the effect of thalidomide…”
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Prognostic Value of Cardiovascular Magnetic Resonance and Single-Photon Emission Computed Tomography in Suspected Coronary Heart Disease: Long-Term Follow-up of a Prospective, Diagnostic Accuracy Cohort Study by Greenwood, John P, Herzog, Bernhard A, Brown, Julia M, Everett, Colin C, Nixon, Jane, Bijsterveld, Petra, Maredia, Neil, Motwani, Manish, Dickinson, Catherine J, Ball, Stephen G, Plein, Sven

“…There are no prospective, prognostic data comparing cardiovascular magnetic resonance (CMR) and single-photon emission computed tomography (SPECT) in the same…”
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An international, multicentre, prospective, randomised, controlled, unblinded, parallel-group trial of robotic-assisted versus standard laparoscopic surgery for the curative treatment of rectal cancer by Collinson, Fiona J., Jayne, David G., Pigazzi, Alessio, Tsang, Charles, Barrie, Jennifer M., Edlin, Richard, Garbett, Christopher, Guillou, Pierre, Holloway, Ivana, Howard, Helen, Marshall, Helen, McCabe, Christopher, Pavitt, Sue, Quirke, Phil, Rivers, Carly S., Brown, Julia M. B.

“…Purpose There is growing enthusiasm for robotic-assisted laparoscopic operations across many surgical specialities, including colorectal surgery, often not…”
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Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts by Shin, Minwook, Chan, Io Long, Cao, Yuming, Gruntman, Alisha M, Lee, Jonathan, Sousa, Jacquelyn, Rodríguez, Tomás C, Echeverria, Dimas, Devi, Gitali, Debacker, Alexandre J, Moazami, Michael P, Krishnamurthy, Pranathi Meda, Rembetsy-Brown, Julia M, Kelly, Karen, Yukselen, Onur, Donnard, Elisa, Parsons, Teagan J, Khvorova, Anastasia, Sontheimer, Erik J, Maehr, René, Garber, Manuel, Watts, Jonathan K

“…Abstract The lung is a complex organ with various cell types having distinct roles. Antisense oligonucleotides (ASOs) have been studied in the lung, but it has…”
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Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo by Sarli, Samantha L, Fakih, Hassan H, Kelly, Karen, Devi, Gitali, Rembetsy-Brown, Julia M, McEachern, Holly R, Ferguson, Chantal M, Echeverria, Dimas, Lee, Jonathan, Sousa, Jacquelyn, Sleiman, Hanadi F, Khvorova, Anastasia, Watts, Jonathan K

“…Glioblastoma multiforme is a universally lethal brain tumor that largely resists current surgical and drug interventions. Despite important advancements in…”
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Genomic representativeness and chimerism in large collections of SAGs and MAGs of marine prokaryoplankton by Chang, Tianyi, Gavelis, Gregory S, Brown, Julia M, Stepanauskas, Ramunas

“…Single amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) are the predominant sources of information about the coding potential of uncultured…”
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Recommendations for designing and analysing multi-arm non-inferiority trials: a review of methodology and current practice by Emmerson, Jake, Todd, Susan, Brown, Julia M

“…Abstract Background and purpose Multi-arm non-inferiority (MANI) trials, here defined as non-inferiority trials with multiple experimental treatment arms, can…”
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High-dose chemotherapy plus autologous stem-cell transplantation as consolidation therapy in patients with relapsed multiple myeloma after previous autologous stem-cell transplantation (NCRI Myeloma X Relapse [Intensive trial]): a randomised, open-label, phase 3 trial by Cook, Gordon, Prof, Williams, Cathy, MD, Brown, Julia M, Prof, Cairns, David A, PhD, Cavenagh, Jamie, Prof, Snowden, John A, Prof, Ashcroft, A John, PhD, Fletcher, Marie, BSc, Parrish, Chris, MBBS, Yong, Kwee, Prof, Cavet, Jim, PhD, Hunter, Hanna, MD, Bird, Jenny M, MD, Chalmers, Anna, BSc, O'Connor, Sheila, PhD, Drayson, Mark T, Prof, Morris, Treen C M, Prof

“…Summary Background Relapsed multiple myeloma has no standard treatment, and the role of autologous stem-cell transplantation (ASCT) has not been fully defined…”
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