Search Results - "Brown, Jordan S"

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    GLH/VASA helicases promote germ granule formation to ensure the fidelity of piRNA-mediated transcriptome surveillance by Chen, Wenjun, Brown, Jordan S., He, Tao, Wu, Wei-Sheng, Tu, Shikui, Weng, Zhiping, Zhang, Donglei, Lee, Heng-Chi

    Published in Nature communications (09-09-2022)
    “…piRNAs function as guardians of the genome by silencing non-self nucleic acids and transposable elements in animals. Many piRNA factors are enriched in…”
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  2. 2

    pirScan: a webserver to predict piRNA targeting sites and to avoid transgene silencing in C. elegans by Wu, Wei-Sheng, Huang, Wei-Che, Brown, Jordan S, Zhang, Donglei, Song, Xiaoyan, Chen, Hao, Tu, Shikui, Weng, Zhiping, Lee, Heng-Chi

    Published in Nucleic acids research (02-07-2018)
    “…Abstract pirScan is a web-based tool for identifying C. elegans piRNA-targeting sites within a given mRNA or spliced DNA sequence. The purpose of our tool is…”
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    Condensate cooperativity underlies transgenerational gene silencing by Du, Zhenzhen, Shi, Kun, Brown, Jordan S., He, Tao, Wu, Wei-Sheng, Zhang, Ying, Lee, Heng-Chi, Zhang, Donglei

    Published in Cell reports (Cambridge) (29-08-2023)
    “…Biomolecular condensates have been shown to interact in vivo, yet it is unclear whether these interactions are functionally meaningful. Here, we demonstrate…”
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    CLASH Analyst: A Web Server to Identify In Vivo RNA-RNA Interactions from CLASH Data by Wu, Wei-Sheng, Brown, Jordan S, Chen, Pin-Hao, Shiue, Sheng-Cian, Lee, Dong-En, Lee, Heng-Chi

    Published in Non-coding RNA (12-01-2022)
    “…Non-coding RNAs, such as miRNAs and piRNAs, play critical roles in gene regulation through base-pairing interactions with their target molecules. The recent…”
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  5. 5

    Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing by Brown, Jordan S, Zhang, Donglei, Gaylord, Olivia, Chen, Wenjun, Lee, Heng-Chi

    Published in Genetics (Austin) (09-08-2023)
    “…Abstract Metazoans guard their germlines against transposons and other foreign transcripts with PIWI-interacting RNAs (piRNAs). Due to the robust heritability…”
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  6. 6

    piRTarBase: a database of piRNA targeting sites and their roles in gene regulation by Wu, Wei-Sheng, Brown, Jordan S, Chen, Tsung-Te, Chu, Yu-Han, Huang, Wei-Che, Tu, Shikui, Lee, Heng-Chi

    Published in Nucleic acids research (08-01-2019)
    “…Abstract PIWI-interacting RNAs (piRNAs) are a class of small noncoding RNAs that guard animal genomes against mutation by silencing transposons. In addition,…”
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    The Dynamics of P Granule Liquid Droplets Are Regulated by the Caenorhabditis elegans Germline RNA Helicase GLH-1 via Its ATP Hydrolysis Cycle by Chen, Wenjun, Hu, Yabing, Lang, Charles F, Brown, Jordan S, Schwabach, Sierra, Song, Xiaoyan, Zhang, Ying, Munro, Edwin, Bennett, Karen, Zhang, Donglei, Lee, Heng-Chi

    Published in Genetics (Austin) (01-06-2020)
    “…Abstract Germ granules, also known as P granules in Caenorhabditis elegans, are phase-separated cellular bodies that are frequently found at the perinuclear…”
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  8. 8

    Transcriptome-wide analyses of piRNA binding sites suggest distinct mechanisms regulate piRNA binding and silencing in C. elegans by Wu, Wei-Sheng, Brown, Jordan S, Shiue, Sheng-Cian, Chung, Chi-Jung, Lee, Dong-En, Zhang, Donglei, Lee, Heng-Chi

    Published in RNA (Cambridge) (01-05-2023)
    “…PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposon mRNAs and some endogenous mRNAs in various animals. However, piRNAs only…”
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  9. 9

    The Dynamics of P Granule Liquid Droplets Are Regulated by the Caenorhabditis elegans Germline RNA Helicase GLH-1 via Its ATP Hydrolysis Cycle by Chen, Wenjun, Hu, Yabing, Lang, Charles F, Brown, Jordan S, Schwabach, Sierra, Song, Xiaoyan, Zhang, Ying, Munro, Edwin, Bennett, Karen, Zhang, Donglei, Lee, Heng-Chi

    Published in Genetics (Austin) (01-06-2020)
    “…Germ granules, also known as P granules in Caenorhabditis elegans, are phase-separated cellular bodies that are frequently found at the perinuclear region of…”
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    Journal Article
  10. 10

    Varicocelectomy in the subfertile male: a ten-year experience with 295 cases by Brown, J S

    Published in Fertility and sterility (01-09-1976)
    “…During a 10-year period 295 varicocelectomies were performed in subfertile males. Results of follow-up studies indicate the following: (1) Semen quality…”
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    Experience with Kaufman III procedure for urinary incontinence by Brown, J S

    Published in Urology (Ridgewood, N.J.) (01-02-1975)
    “…The Kaufman III procedure for urinary incontinence is an effective means of treating postprostatectomy incontinence. The technique was modified by the routine…”
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    The effect of orally administered androgens on sperm motility by Brown, J S

    Published in Fertility and sterility (01-04-1975)
    “…The administration of oral androgens increased sperm motility to normal in 30 (52%) of 58 men whose impaired motility was the only defect in their semen…”
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    The role of internal spermatic vein plasma catecholamine determinations in subfertile men with varicoceles by Cohen, M S, Plaine, L, Brown, J S

    Published in Fertility and sterility (01-12-1975)
    “…Catecholamine concentrations were determined in left spermatic vein blood of 18 patients with varicocele. These values were compared with concentrations of…”
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    Carcinoid tumor of kidney by Ghazi, M R, Brown, J S, Warner, R S

    Published in Urology (Ridgewood, N.J.) (01-01-1979)
    “…A case of carcinoid tumor of the kidney is reported. Pathologic findings of the tumor, clinical manifestation, and treatment are discussed…”
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