Search Results - "Brown, Jenny"
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Uncertainty in estuarine extreme water level predictions due to surge-tide interaction
Published in PloS one (26-10-2018)“…Storm surge is often the greatest threat to life and critical infrastructures during hurricanes and violent storms. Millions of people living in low-lying…”
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Rethinking the role of the brain in glucose homeostasis and diabetes pathogenesis
Published in The Journal of clinical investigation (01-08-2019)“…The brain plays a major role in homeostatic processes ranging from control of body temperature and fat mass to blood pressure and volume. Tight regulation of…”
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The release of legacy phosphorus from deforestation-derived sediments in shallow, coastal lake Forsyth/Te Roto o Wairewa
Published in New Zealand journal of marine and freshwater research (03-07-2021)“…Phosphorus (P) release from sediments accumulating since catchment deforestation, has been linked to algal blooms which have occurred in Lake Wairewa…”
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Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain
Published in Diabetes (New York, N.Y.) (01-03-2019)“…We recently reported that in rodent models of type 2 diabetes (T2D), a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1)…”
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The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1
Published in Diabetes (New York, N.Y.) (01-05-2019)“…In rodent models of type 2 diabetes (T2D), sustained remission of diabetic hyperglycemia can be induced by a single intracerebroventricular (icv) injection of…”
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214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The hypothalamic arcuate nucleus-median eminence (ARC-ME) is a target for sustained diabetes remission induced by fibroblast growth factor 1 (FGF1). To…”
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The effects of entombment on water chemistry and bacterial assemblages in closed cryoconite holes on Antarctic glaciers
Published in FEMS microbiology ecology (01-12-2015)“…Closed cryoconite holes (CCHs) are small aquatic ecosystems enclosed in glacier surface ice, and they collectively contribute substantial aquatic habitat to…”
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Prebiotic‐supplemented partially hydrolysed cow's milk formula for the prevention of eczema in high‐risk infants: a randomized controlled trial
Published in Allergy (Copenhagen) (01-05-2016)“…Background Prevention guidelines for infants at high risk of allergic disease recommend hydrolysed formula if formula is introduced before 6 months, but…”
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1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Defective glucoregulatory neurocircuit activity within the hypothalamic arcuate nucleus (ARC) is implicated in the pathogenesis of type 2 diabetes (T2D). In…”
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Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
Published in iScience (24-09-2021)“…The capacity of the brain to elicit sustained remission of hyperglycemia in rodent models of type 2 diabetes following intracerebroventricular (icv) injection…”
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Perineuronal net formation during the critical period for neuronal maturation in the hypothalamic arcuate nucleus
Published in Nature metabolism (01-02-2019)“…In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC) 1 , a…”
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Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats
Published in Nature metabolism (01-10-2020)“…We recently showed that perineuronal nets (PNNs) enmesh glucoregulatory neurons in the arcuate nucleus (Arc) of the mediobasal hypothalamus (MBH) 1 , but…”
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Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Published in JCI insight (08-09-2022)“…In rodent models of type 2 diabetes (T2D), central administration of FGF1 normalizes elevated blood glucose levels in a manner that is sustained for weeks or…”
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The Pyramid Trough Wetland: environmental and biological diversity in a newly created Antarctic protected area
Published in FEMS microbiology ecology (01-11-2012)“…Abstract The Pyramid Trough (Lat 78°S) has recently gained protection under the Antarctic Treaty system, owing to its wetland values. Here, we describe the…”
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Combined micro-osmotic pump infusion and intracerebroventricular injection to study FGF1 signaling pathways in the mouse brain
Published in STAR protocols (17-06-2022)“…Intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) elicits remission of diabetic hyperglycemia in rodent models of type 2 diabetes…”
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We Don't Need Your Help, But Will You Please Fix Our Children
Published in Australian and New Zealand journal of family therapy (01-06-2008)“…A Bowen Family Systems therapist employs concepts of triangles and the family projection process to view a child's symptoms as embedded in the broader family…”
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Biological-physical interactions are fundamental to understanding and managing coastal dynamics
Published in Royal Society open science (12-07-2023)“…There is an urgent need to address coastal dynamics as a fundamental interaction between physical and biological processes, particularly when trying to predict…”
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Assessing the nature of the combined effects of copper and zinc on estuarine infaunal communities
Published in Environmental pollution (1987) (01-01-2011)“…Elevated levels of copper and zinc in sediment have been shown to adversely affect estuarine infauna. We investigated the additivity of the combined effects of…”
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Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Published in Nature communications (07-09-2020)“…In rodent models of type 2 diabetes (T2D), sustained remission of hyperglycemia can be induced by a single intracerebroventricular (icv) injection of…”
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