Search Results - "Brown, Graham V"

Functional Antibodies and Protection against Blood-stage Malaria by Teo, Andrew, Feng, Gaoqian, Brown, Graham V, Beeson, James G, Rogerson, Stephen J

“…Numerous efforts to understand the functional roles of antibodies demonstrated that they can protect against malaria. However, it is unclear which antibody…”
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A review of malaria vaccine clinical projects based on the WHO rainbow table by Schwartz, Lauren, Brown, Graham V, Genton, Blaise, Moorthy, Vasee S

“…Development and Phase 3 testing of the most advanced malaria vaccine, RTS,S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials…”
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A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression by Josling, Gabrielle A., Petter, Michaela, Oehring, Sophie C., Gupta, Archna P., Dietz, Olivier, Wilson, Danny W., Schubert, Thomas, Längst, Gernot, Gilson, Paul R., Crabb, Brendan S., Moes, Suzette, Jenoe, Paul, Lim, Shu Wei, Brown, Graham V., Bozdech, Zbynek, Voss, Till S., Duffy, Michael F.

“…During red-blood-cell-stage infection of Plasmodium falciparum, the parasite undergoes repeated rounds of replication, egress, and invasion. Erythrocyte…”
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The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes by Tonkin-Hill, Gerry Q, Trianty, Leily, Noviyanti, Rintis, Nguyen, Hanh H T, Sebayang, Boni F, Lampah, Daniel A, Marfurt, Jutta, Cobbold, Simon A, Rambhatla, Janavi S, McConville, Malcolm J, Rogerson, Stephen J, Brown, Graham V, Day, Karen P, Price, Ric N, Anstey, Nicholas M, Papenfuss, Anthony T, Duffy, Michael F

“…Within the human host, the malaria parasite Plasmodium falciparum is exposed to multiple selection pressures. The host environment changes dramatically in…”
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Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass by Duffy, Michael F., Tonkin-Hill, Gerry Q., Trianty, Leily, Noviyanti, Rintis, Nguyen, Hanh H. T., Rambhatla, Janavi S., McConville, Malcolm J., Rogerson, Stephen J., Brown, Graham V., Price, Ric N., Anstey, Nicholas M., Day, Karen P., Papenfuss, Anthony T.

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Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter by Petter, Michaela, Lee, Chin Chin, Byrne, Timothy J, Boysen, Katja E, Volz, Jennifer, Ralph, Stuart A, Cowman, Alan F, Brown, Graham V, Duffy, Michael F

“…Plasmodium falciparum employs antigenic variation to evade the human immune response by switching the expression of different variant surface antigens encoded…”
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High numbers of circulating pigmented polymorphonuclear neutrophils as a prognostic marker for decreased birth weight during malaria in pregnancy by Chua, Caroline Lin Lin, Robinson, Leanne J., Baiwog, Francesca, Stanisic, Danielle I., Hamilton, John A., Brown, Graham V., Rogerson, Stephen J., Boeuf, Philippe

“…[Display omitted] •The prognostic value of pigmented leukocyte counts in gestational malaria was tested.•We determined circulating pigmented leukocyte counts…”
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A Recombinant Blood-Stage Malaria Vaccine Reduces Plasmodium falciparum Density and Exerts Selective Pressure on Parasite Populations in a Phase 1-2b Trial in Papua New Guinea by Genton, Blaise, Betuela, Inoni, Felger, Ingrid, Al-Yaman, Fadwa, Anders, Robin F., Saul, Allan, Rare, Lawrence, Baisor, Moses, Lorry, Kerry, Brown, Graham V., Pye, David, Irving, David O., Smith, Thomas A., Beck, Hans-Peter, Alpers, Michael P.

“…The malaria vaccine Combination B comprises recombinant Plasmodium falciparum ring-infected erythrocyte surface antigen and 2 merozoite surface proteins (MSP1…”
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Soluble CD163, a product of monocyte/macrophage activation, is inversely associated with haemoglobin levels in placental malaria by Chua, Caroline Lin Lin, Brown, Graham V, Hamilton, John A, Molyneux, Malcolm E, Rogerson, Stephen J, Boeuf, Philippe

“…In Plasmodium falciparum malaria, activation of monocytes and macrophages (monocytes/macrophages) can result in the production of various inflammatory…”
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Ethical evaluation of immigration screening policy for latent tuberculosis infection by Denholm, Justin T., McBryde, Emma S., Brown, Graham V.

“…In Australia and New Zealand, immigration screening policy relating to tuberculosis is targeted towards identifying potential new arrivals with active…”
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A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD by Hutchinson, Anastasia F, Ghimire, Anil K, Thompson, Michelle A, Black, Jim F, Brand, Caroline A, Lowe, Adrian J, Smallwood, David M, Vlahos, Ross, Bozinovski, Steven, Brown, Graham V, Anderson, Gary P, Irving, Louis B

“…Summary Respiratory viruses are associated with severe acute exacerbations of chronic obstructive pulmonary disease (COPD) in hospitalized patients. However,…”
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Inhibition of Dendritic Cell Maturation by Malaria Is Dose Dependent and Does Not Require Plasmodium falciparum Erythrocyte Membrane Protein 1 by Elliott, Salenna R, Spurck, Timothy P, Dodin, Joelle M, Maier, Alexander G, Voss, Till S, Yosaatmadja, Francisca, Payne, Paul D, McFadden, Geoffrey I, Cowman, Alan F, Rogerson, Stephen J, Schofield, Louis, Brown, Graham V

“…Red blood cells infected with Plasmodium falciparum (iRBCs) have been shown to modulate maturation of human monocyte-derived dendritic cells (DCs), interfering…”
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Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission by Teo, Andrew, Hasang, Wina, Randall, Louise M, Unger, Holger W, Siba, Peter M, Mueller, Ivo, Brown, Graham V, Rogerson, Stephen J

“…Regular anti-malarial therapy in pregnancy, a pillar of malaria control, may affect malaria immunity, with therapeutic implications in regions of reducing…”
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Transcribed var Genes Associated with Placental Malaria in Malawian Women by Duffy, Michael F, Caragounis, Aphrodite, Noviyanti, Rintis, Kyriacou, Helen M, Choong, Ee Ken, Boysen, Katja, Healer, Julie, Rowe, J. Alexandra, Molyneux, Malcolm E, Brown, Graham V, Rogerson, Stephen J

“…Determiningthe diversity of PfEMP1 sequences expressed by Plasmodiumfalciparum-infected erythrocytes isolated from placentas isimportant for attempts to…”
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MALVAC 2012 scientific forum: accelerating development of second-generation malaria vaccines by Vannice, Kirsten S, Brown, Graham V, Akanmori, Bartholomew D, Moorthy, Vasee S

“…The World Health Organization (WHO) convened a malaria vaccines committee (MALVAC) scientific forum from 20 to 21 February 2012 in Geneva, Switzerland, to…”
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VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum by Duffy, Michael F., Maier, Alexander G., Byrne, Timothy J., Marty, Allison J., Elliott, Salenna R., O’Neill, Matthew T., Payne, Paul D., Rogerson, Stephen J., Cowman, Alan F., Crabb, Brendan S., Brown, Graham V.

“…Malaria during pregnancy causes serious disease that is associated with sequestration in the placenta of Plasmodium falciparum infected erythrocytes that…”
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Plasmodium falciparum Isolates from Infected Pregnant Women and Children Are Associated with Distinct Adhesive and Antigenic Properties by Beeson, James G., Brown, Graham V., Molyneux, Malcolm E., Mhango, Chisale, Dzinjalamala, Fraction, Rogerson, Stephen J.

“…Plasmodium falciparum malaria during pregnancy is an important cause of maternal and infant morbidity and mortality. Accumulation of large numbers of P…”
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Building quality in health: the need for clinical researchers by Brown, Graham V, Sorrell, Tania C

“…Integration of research and education into health care delivery leads to improved outcomes and facilitates rapid translation of results into policy and…”
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Antibodies to Variant Surface Antigens of Plasmodium falciparum–Infected Erythrocytes and Adhesion Inhibitory Antibodies Are Associated with Placental Malaria and Have Overlapping and Distinct Targets by Beeson, James G., Mann, Emily J., Elliott, Salenna R., Lema, Valentino M., Tadesse, Eyob, Molyneux, Malcolm E., Brown, Graham V., Rogerson, Stephen J.

“…We measured antibodies to chondroitin sulfate A (CSA)–binding and placental Plasmodium falciparum–infected red blood cells (PRBCs) among pregnant women with or…”
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Plasmodium falciparum–Infected Erythrocytes Demonstrate Dual Specificity for Adhesion to Hyaluronic Acid and Chondroitin Sulfate A and Have Distinct Adhesive Properties by Beeson, James G., Brown, Graham V.

“…Hyaluronic acid (HA) and chondroitin sulfate A (CSA) have been identified as receptors for adhesion of Plasmodium falciparum–infected erythrocytes (IEs) and…”
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