Search Results - "Brown, Gavin D."

Fire safety protection motivation and preparedness in Irish apartments: A Post-Grenfell analysis by Brown, Gavin D., Largey, Ann, McMullan, Caroline, Daffy, Paul

“…•Those who worry most about fire are less likely to evacuate in response to an alarm.•Higher worry about fire increases frequency of smoke detector…”
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Preparing to respond: Irish nurses' perceptions of preparedness for an influenza pandemic by McMullan, Caroline, Brown, Gavin D., O'Sullivan, David

“…•This study is on preparedness for an influenza pandemic in Ireland.•Focus is placed on the professional and personal concerns of nurses.•90% of nurses were…”
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The influence of expertise on perceived and actual household disaster preparedness by Brown, Gavin D., Largey, Ann, McMullan, Caroline

“…•Experts' households are better prepared for a disaster than those of non-experts.•Experts appear no more accurate at predicting their preparedness than…”
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Flight crew evaluation of the flight time limitations regulation by Efthymiou, Marina, Whiston, Sinead, O'Connell, John F., Brown, Gavin D.

“…•Safety should not be compromised for maximum aircraft and labor utilisation.•Fatigue is under-reported and is a real risk to safety in the aviation…”
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Do industrial incidents in the chemical sector create equity market contagion? by Brown, Gavin D., Corbet, Shaen, McMullan, Caroline, Sharma, Ruchira

“…This paper examines a number of US chemical industry incidents and their effect on equity prices of the incident company. Furthermore, this paper then examines…”
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Pharmacokinetic Evaluation of N-[2-(Dimethylamino)Ethyl]Acridine-4-Carboxamide in Patients by Positron Emission Tomography by SALEEM, Azeem, HARTE, Robert J, PRICE, Pat M, ABOAGYE, Eric O, MATTHEWS, Julian C, OSMAN, Safiye, BRADY, Frank, LUTHRA, Sajinder K, BROWN, Gavin D, BLEEHEN, Norman, CONNORS, Tom, JONES, Terry

“…To evaluate tumor, normal tissue, and plasma pharmacokinetics of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA). The study aimed to determine the…”
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High‐Affinity “Click” RGD Peptidomimetics as Radiolabeled Probes for Imaging αvβ3 Integrin by Piras, Monica, Testa, Andrea, Fleming, Ian N., Dall'Angelo, Sergio, Andriu, Alexandra, Menta, Sergio, Mori, Mattia, Brown, Gavin D., Forster, Duncan, Williams, Kaye J., Zanda, Matteo

“…Nonpeptidic Arg‐Gly‐Asp (RGD)‐mimic ligands were designed and synthesized by click chemistry between an arginine–azide mimic and an aspartic acid–alkyne mimic…”
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High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging α v β 3 Integrin by Piras, Monica, Testa, Andrea, Fleming, Ian N, Dall'Angelo, Sergio, Andriu, Alexandra, Menta, Sergio, Mori, Mattia, Brown, Gavin D, Forster, Duncan, Williams, Kaye J, Zanda, Matteo

“…Nonpeptidic Arg-Gly-Asp (RGD)-mimic ligands were designed and synthesized by click chemistry between an arginine-azide mimic and an aspartic acid-alkyne mimic…”
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Metabolic activation of temozolomide measured in vivo using positron emission tomography by SALEEM, Azeem, BROWN, Gavin D, JONES, Terry, PRICE, Pat, BRADY, Frank, ABOAGYE, Eric O, OSMAN, Safiye, LUTHRA, Sajinder K, RANICAR, Alex S. O, BROCK, Cathryn S, STEVENS, Malcolm F. G, NEWLANDS, Edward

“…The purpose of this research was to quantitate and confirm the mechanism of in vivo metabolic activation of temozolomide. The secondary aims were to evaluate…”
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The impact of gender on risk perception: Implications for EU member states’ national risk assessment processes by Brown, Gavin D., Largey, Ann, McMullan, Caroline

“…This study examined the influence of gender on individual risk perception. The analysis covered 17 involuntary risks and examined the effects of gender on…”
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Amyloid PET using 18F-AV45 in Frontotemporal Dementia by Vardy, Emma R.L.C, Hinz, Rainer, Langheinrich, Tobias, Snowden, Julie, Gerhard, Alex, Richardson, Anna M.T, Anton, Jose, Brown, Gavin D, Neary, David, Herholz, Karl

“…Background:18F-AV-45 (Florbetapir F-18) is a novel positron emission tomography (PET) tracer for in vivo imaging of cerebral amyloid. We present preliminary…”
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Antitumor Imidazotetrazines. 40. Radiosyntheses of [4-11C-C arbonyl]- and [3-N-11C-M ethyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (Temozolomide) for Positron Emission Tomography (PET) Studies by Brown, Gavin D, Luthra, Sajinder K, Brock, Cathryn S, Stevens, Malcolm F. G, Price, Patricia M, Brady, Frank

“…8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide, 1) is an anticancer prodrug. As part of investigations to probe its postulated…”
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Tutorial on Tom and Jerry: the two smoothings of the anticanonical cone over $\mathbb{P}$(1, 2, 3) by Brown, Gavin D., Reid, Miles, Stevens, Jan

“…This is a first introduction to unprojection methods, and more specifically to Tom and Jerry unprojections. These two harmless tricks deserve to be better…”
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Weathering the storm: Developing a user-centric weather forecast and warning system for Ireland by Brown, Gavin D., Largey, Ann, McMullan, Caroline, Reilly, Niamh, Sahdev, Muskan

“…This paper appraises current usage and future weather service needs in Ireland. The data for this study were collected using a household preparedness…”
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Two routes to [11C-carbonyl]organo-isocyanates utilizing [11C]phosgene ([11C]organo-isocyanates from [11C]phosgene) by BROWN, Gavin D, HENDERSON, David, STEEL, Colin, LUTHRA, Sajinder, PRICE, Patricia M, BRADY, Frank

“…Two generic radiosynthetic routes for the preparation of [11C-carbonyl]isocyanates have been developed. Reaction of N-organo-sulfinylamines; RNSO, (R = Me, Et,…”
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High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging [alpha]v[beta]3 Integrin by Piras, Monica, Testa, Andrea, Fleming, Ian N, Dall'Angelo, Sergio, Andriu, Alexandra, Menta, Sergio, Mori, Mattia, Brown, Gavin D, ster, Duncan, Williams, Kaye J, Zanda, Matteo

“…Nonpeptidic Arg-Gly-Asp (RGD)-mimic ligands were designed and synthesized by click chemistry between an arginine-azide mimic and an aspartic acid-alkyne mimic…”
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Inhibition of quorum sensing and biofilm formation in Vibrio harveyi by 4-fluoro-DPD; a novel potent inhibitor of signalling by Kadirvel, Manikandan, Fanimarvasti, Fariba, Forbes, Sarah, McBain, Andrew, Gardiner, John M, Brown, Gavin D, Freeman, Sally

“…(S)-4,5-Dihydroxypentane-2,3-dione [(S)-DPD, (1)] is a precursor for , a quorum sensing signalling molecule for inter- and intra-species bacterial…”
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IC‐P‐085: Amyloid PET using 18F‐AV45 in Frontotemporal Dementia by Vardy, Emma R.L.C., Hinz, Rainer, Langheinrich, Tobias, Snowden, Julie, Gerhard, Alex, Richardson, Anna M.T., Anton, Jose, Brown, Gavin D., Neary, David, Herholz, Karl

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Antitumor imidazotetrazines. 40.1 radiosyntheses of [4-11C-carbonyl]: and [3-N-11C-methyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) for positron emission tomography (PET) studies by BROWN, Gavin D, LUTHRA, Sajinder K, BROCK, Cathryn S, STEVENS, Malcolm F. G, PRICE, Patricia M, BRADY, Frank

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Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues by OSMAN, Safiye, ROWLINSON-BUSZA, Gail, PRICE, Pat M, LUTHRA, Sajinder K, ABOAGYE, Eric O, BROWN, Gavin D, BRADY, Frank, MYERS, Ralph, GAMAGE, Swarna A, DENNY, William A, BAGULEY, Bruce C

“…The tricyclic carboxamide N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) is a DNA-intercalating agent capable of inhibiting both topoisomerases I and…”
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