Search Results - "Brown, Dennis T"

Alphavirus Genome Delivery Occurs Directly at the Plasma Membrane in a Time- and Temperature-Dependent Process by Vancini, Ricardo, Wang, Gongbo, Ferreira, Davis, Hernandez, Raquel, Brown, Dennis T

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Tizoxanide Antiviral Activity on Dengue Virus Replication by Yamamoto, Kristie A, Blackburn, Kevin, Goshe, Michael B, Brown, Dennis T, Migoswski, Edimilson, Campanhon, Isabele B, Moreira, Monica F, Ferreira, Davis F, Soares, Marcia R

“…Dengue virus is an important circulating arbovirus in Brazil responsible for high morbidity and mortality worldwide, representing a huge economic and social…”
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Role of the Vacuolar-ATPase in Sindbis Virus Infection by HUNT, Sabrina R, HERNANDEZ, Raquel, BROWN, Dennis T

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Differential Incorporation of Cholesterol by Sindbis Virus Grown in Mammalian or Insect Cells by HAFER, Amanda, WHITTLESEY, Rebecca, BROWN, Dennis T, HERNANDEZ, Raquel

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Chikungunya Virus Host Range E2 Transmembrane Deletion Mutants Induce Protective Immunity against Challenge in C57BL/6J Mice by Piper, Amanda, Ribeiro, Mariana, Smith, Katherine M, Briggs, Caitlin M, Huitt, Emerson, Nanda, Kavita, Spears, Carla J, Quiles, Michelle, Cullen, John, Thomas, Malcolm E, Brown, Dennis T, Hernandez, Raquel

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Conformational Changes in Sindbis Virus Induced by Decreased pH Are Revealed by Small-Angle Neutron Scattering by He, Lilin, Piper, Amanda, Meilleur, Flora, Hernandez, Raquel, Heller, William T, Brown, Dennis T

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Structural Differences Observed in Arboviruses of the Alphavirus and Flavivirus Genera by Hernandez, Raquel, Paredes, Angel, Brown, Dennis T.

“…Arthropod borne viruses have developed a complex life cycle adapted to alternate between insect and vertebrate hosts. These arthropod-borne viruses belong…”
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Sindbis Virus Conformational Changes Induced by a Neutralizing Anti-E1 Monoclonal Antibody by Hernandez, Raquel, Paredes, Angel, Brown, Dennis T

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The Structure of Sindbis Virus Produced from Vertebrate and Invertebrate Hosts as Determined by Small-Angle Neutron Scattering by LILIN HE, PIPER, Amanda, MEILLEUR, Flora, MYLES, Dean A. A, HERNANDEZ, Raquel, BROWN, Dennis T, HELLER, William T

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An alternative pathway for alphavirus entry by Kononchik, Jr, Joseph P, Hernandez, Raquel, Brown, Dennis T

“…The study of alphavirus entry has been complicated by an inability to clearly identify a receptor and by experiments which only tangentially and indirectly…”
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Role of the vacuolar ATPase in the Alphavirus replication cycle by Schuchman, Ryan M., Vancini, Ricardo, Piper, Amanda, Breuer, Denitra, Ribeiro, Mariana, Ferreira, Davis, Magliocca, Joseph, Emmerich, Veronica, Hernandez, Raquel, Brown, Dennis T.

“…We have shown that Alphaviruses can enter cells by direct penetration at the plasma membrane (R. Vancini, G. Wang, D. Ferreira, R. Hernandez, and D. Brown, J…”
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Mutations in the Endodomain of Sindbis Virus Glycoprotein E2 Define Sequences Critical for Virus Assembly by WEST, John, HERNANDEZ, Raquel, FERREIRA, Davis, BROWN, Dennis T

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Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype by Smith, Katherine M, Nanda, Kavita, Spears, Carla J, Ribeiro, Mariana, Vancini, Ricardo, Piper, Amanda, Thomas, Gwynneth S, Thomas, Malcolm E, Brown, Dennis T, Hernandez, Raquel

“…There are over 700 known arboviruses and at least 80 immunologically distinct types that cause disease in humans. Arboviruses are transmitted among vertebrates…”
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Location and Role of Free Cysteinyl Residues in the Sindbis Virus E1 and E2 Glycoproteins by WHITEHURST, Christopher B, SODERBLOM, Erik J, WEST, Michelle L, HERNANDEZ, Raquel, GOSHE, Michael B, BROWN, Dennis T

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Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly by Magliocca, Joseph, Vancini, Ricardo, Hernandez, Raquel, Brown, Dennis T

“…A panel of Sindbis virus mutants that were suspected to have deficiencies in one or more aspects of their replication cycles was examined in baby hamster…”
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Deletions in the Transmembrane Domain of a Sindbis Virus Glycoprotein Alter Virus Infectivity, Stability, and Host Range by Hernandez, Raquel, Sinodis, Christine, Horton, Michelle, Ferreira, Davis, Yang, Chunning, Brown, Dennis T

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Single Amino Acid Insertions at the Junction of the Sindbis Virus E2 Transmembrane Domain and Endodomain Disrupt Virus Envelopment and Alter Infectivity by HERNANDEZ, Raquel, FERREIRA, Davis, SINODIS, Christine, LITTON, Katherine, BROWN, Dennis T

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Insect response to alphavirus infection—Establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage by Mudiganti, Usharani, Hernandez, Raquel, Brown, Dennis T.

“…Alphavirus persistence in the insect vector is an essential element in the vector–host transmission cycle of the virus and provides a model to study the…”
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Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly by Lee, Sukyeong, Owen, Katherine E, Choi, Hok-Kin, Lee, Heuiran, Lu, Guoguang, Wengler, Gerd, Brown, Dennis T, Rossmann, Michael G, Kuhn, Richard J

“…Background: Many enveloped viruses exit cells by budding from the plasma membrane. The driving force for budding is the interaction of an inner protein…”
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Three-Dimensional Structure of a Membrane-Containing Virus by PAREDES, A. M, BROWN, D. T, ROTHNAGEL, R, WAH CHIU, SCHOEPP, R. J, JOHNSTON, R. E, VENKATARAM PRASAD, B. V

“…The structure of Sindbis virus was determined by electron cryomicroscopy. The virion contains two icosahedral shells of viral-encoded proteins separated by a…”
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