Search Results - "Brown, David"
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Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?
Published in Nature reviews. Drug discovery (01-12-2015)“…Key Points Concern over antibiotic resistance is growing. Resistance of up to 50% has been reported in some regions, including resistance to carbapenems, our…”
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Trends in Bronchiolitis Hospitalizations in the United States, 2000―2009
Published in Pediatrics (Evanston) (01-07-2013)“…To examine temporal trend in the national incidence of bronchiolitis hospitalizations, use of mechanical ventilation, and hospital charges between 2000 and…”
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Emergency department triage prediction of clinical outcomes using machine learning models
Published in Critical care (London, England) (22-02-2019)“…Development of emergency department (ED) triage systems that accurately differentiate and prioritize critically ill from stable patients remains challenging…”
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4
Microglia and the aging brain: are senescent microglia the key to neurodegeneration?
Published in Journal of neurochemistry (01-12-2019)“…The single largest risk factor for etiology of neurodegenerative diseases like Alzheimer’s disease is increased age. Therefore, understanding the changes that…”
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Association of Prehospital Advanced Airway Management With Neurologic Outcome and Survival in Patients With Out-of-Hospital Cardiac Arrest
Published in JAMA : the journal of the American Medical Association (16-01-2013)“…IMPORTANCE It is unclear whether advanced airway management such as endotracheal intubation or use of supraglottic airway devices in the prehospital setting…”
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Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System
Published in Circulation research (30-01-2015)“…Oxidative stress has long been implicated in cardiovascular disease, but more recently, the role of reactive oxygen species (ROS) in normal physiological…”
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Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study
Published in The Lancet infectious diseases (01-12-2010)“…Summary Background Encephalitis has many causes, but for most patients the cause is unknown. We aimed to establish the cause and identify the clinical…”
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'Don't dream it's over... There's a battle ahead': The AltLJ 50 years on
Published in Alternative law journal (01-09-2024)“…Perusing the pile of AltLJs since 1994 when my reflection, 'Some things change, some stay the same' appeared in the 20- year anniversary edition. Hoping that,…”
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KinKal: A Kinematic Kalman filter Track Fitting Package for the Mu2e Experiment
Published in EPJ Web of conferences (2024)“…Many current physics experiments require precision reconstruction of low-energy particles. One example is the Mu2e experiment, which requires reconstructing an…”
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Socioeconomic and demographic disparities in residential battery storage adoption: Evidence from California
Published in Energy policy (01-05-2022)“…There is growing interest in the adoption of residential battery storage because of its ability to provide bill savings, capture excess solar energy, and…”
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Bariatric Surgery and Emergency Department Visits and Hospitalizations for Heart Failure Exacerbation: Population-Based, Self-Controlled Series
Published in Journal of the American College of Cardiology (01-03-2016)“…The United States is battling obesity and heart failure (HF) epidemics. Although studies have suggested relationships between obesity and HF morbidity, little…”
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Evidence for PMAT- and OCT-like biogenic amine transporters in a probiotic strain of Lactobacillus: Implications for interkingdom communication within the microbiota-gut-brain axis
Published in PloS one (11-01-2018)“…The ability of prokaryotic microbes to produce and respond to neurochemicals that are more often associated with eukaryotic systems is increasingly recognized…”
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Theory and Applications of Robust Optimization
Published in SIAM review (01-01-2011)“…In this paper we survey the primary research, both theoretical and applied, in the area of robust optimization (RO). Our focus is on the computational…”
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Inside the Adverse Childhood Experience Score: Strengths, Limitations, and Misapplications
Published in American journal of preventive medicine (01-08-2020)Get full text
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Using Seroprevalence and Immunisation Coverage Data to Estimate the Global Burden of Congenital Rubella Syndrome, 1996-2010: A Systematic Review
Published in PloS one (10-03-2016)“…The burden of Congenital Rubella Syndrome (CRS) is typically underestimated in routine surveillance. Updated estimates are needed following the recent WHO…”
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The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases
Published in Cell metabolism (04-09-2018)“…MIC-1/GDF15 is a stress response cytokine and a distant member of the transforming growth factor beta (TGFb) superfamily, with no close relatives. It acts via…”
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Finance and Growth at the Firm Level: Evidence from SBA Loans
Published in The Journal of finance (New York) (01-06-2017)“…We analyze linked databases on all SBA loans and lenders and on all U.S. employers to estimate the effects of financial access on employment growth. Estimation…”
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Mutual Fund Flows and Cross-Fund Learning within Families
Published in The Journal of finance (New York) (01-02-2016)“…We develop a model of performance evaluation and fund flows for mutual funds in a family. Family performance has two effects on a member fund's estimated skill…”
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Regulation of neural ion channels by muscarinic receptors
Published in Neuropharmacology (01-07-2018)“…The excitable behaviour of neurons is determined by the activity of their endogenous membrane ion channels. Since muscarinic receptors are not themselves ion…”
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Protective Effect of Natural Rotavirus Infection in an Indian Birth Cohort
Published in The New England journal of medicine (28-07-2011)“…Rotavirus infection is a cause of considerable morbidity, with an estimated 500,000 deaths annually worldwide. This study in Vellore, India, showed that…”
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