Search Results - "Brown, Amanda"
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Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic neuroinflammation
Published in Immunological reviews (01-10-2022)“…Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1 (SPP1) is a fascinating, multifunctional protein expressed in a number…”
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Endosymbionts of Plant-Parasitic Nematodes
Published in Annual review of phytopathology (25-08-2018)“…Some of the most agriculturally important plant-parasitic nematodes (PPNs) harbor endosymbionts. Extensive work in other systems has shown that endosymbionts…”
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Genome Skimming: A Rapid Approach to Gaining Diverse Biological Insights into Multicellular Pathogens
Published in PLoS pathogens (01-08-2016)“…The N50 statistic, a common statistical measure for average length of a set of sequences (see S1 Text for more detail) was 8,863 bp on average for the six PPN…”
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Discovery of a novel Wolbachia in Heterodera expands nematode host distribution
Published in Frontiers in microbiology (25-09-2024)“…Bioinformatics sequence data mining can reveal hidden microbial symbionts that might normally be filtered and removed as contaminants. Data mining can be…”
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Advancing basic and translational research to deepen understanding of the molecular immune‐mediated mechanisms regulating long‐term persistence of HIV‐1 in microglia in the adult human brain
Published in Journal of leukocyte biology (01-11-2022)“…Knowledge about the diversity microglia (MG) type and function in the rodent and human brain has advanced significantly in the last few years. Nevertheless, we…”
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Global survey of hgcA-carrying genomes in marine and freshwater sediments: Insights into mercury methylation processes
Published in Environmental pollution (1987) (01-07-2024)“…Mercury (Hg) methylation is a microbially mediated process that produces methylmercury (MeHg), a bioaccumulative neurotoxin. A highly conserved gene pair,…”
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Staying Well During Pregnancy and the Postpartum: A Pilot Randomized Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Depressive Relapse/Recurrence
Published in Journal of consulting and clinical psychology (01-02-2016)“…Objective: Clinical decision-making regarding the prevention of depression is complex for pregnant women with histories of depression and their health care…”
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Cerebellar Modules and Their Role as Operational Cerebellar Processing Units
Published in Cerebellum (London, England) (01-10-2018)“…The compartmentalization of the cerebellum into modules is often used to discuss its function. What, exactly, can be considered a module, how do they operate,…”
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Assessing Pediatric Resident Needs in Grief and Bereavement Education
Published in Journal of pain and symptom management (01-10-2024)“…Pediatric residents care for dying children during training. Few educational efforts focus on helping trainees better understand their own grief process and…”
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Microbiome Taxonomic and Functional Differences in C3H/HeJ Mice Fed a Long-Term High-Fat Diet with Beef Protein ± Ammonium Hydroxide Supplementation
Published in Nutrients (25-05-2024)“…Studies have suggested that alkalinized foods may reduce the effects of the acidogenic Western diet in promoting obesity, metabolic syndrome, type 2 diabetes,…”
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Understanding how different surfaces and environmental biofilms found in food processing plants affect the spread of COVID-19
Published in PloS one (07-06-2023)“…Meat processing plants have been at the center of the SARS-CoV-2 pandemic, with a recent report citing 90% of US facilities having multiple outbreaks during…”
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Flexible automation accelerates materials discovery
Published in Nature materials (01-07-2022)“…Automated experiments can accelerate research and development. ‘Flexible automation’ enables the cost- and time-effective design, construction and…”
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Discovery of Early-Branching Wolbachia Reveals Functional Enrichment on Horizontally Transferred Genes
Published in Frontiers in microbiology (25-04-2022)“…is a widespread endosymbiont of insects and filarial nematodes that profoundly influences host biology. has also been reported in rhizosphere hosts, where its…”
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Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake
Published in BMC microbiology (20-05-2008)“…Fosmidomycin is a phosphonic antibiotic which inhibits 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr), the first committed step of the non-mevalonate…”
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Microglial- neuronal crosstalk in chronic viral infection through mTOR, SPP1/OPN and inflammasome pathway signaling
Published in Frontiers in immunology (2024)“…HIV-infection of microglia and macrophages (MMs) induces neuronal injury and chronic release of inflammatory stimuli through direct and indirect molecular…”
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HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment
Published in Nature reviews. Neurology (01-04-2016)“…Key Points Despite entering the era of combination antiretroviral therapy (CART), HIV-associated neurocognitive disorder (HAND) remains prevalent; however,…”
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Population genomics of a symbiont in the early stages of a pest invasion
Published in Molecular ecology (01-03-2014)“…Invasive species often depend on microbial symbionts, but few studies have examined the evolutionary dynamics of symbionts during the early stages of an…”
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Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples
Published in Journal of clinical microbiology (01-07-2015)“…The rapid identification of antimicrobial resistance is essential for effective treatment of highly resistant Mycobacterium tuberculosis. Whole-genome…”
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Divergent endophytic viromes and phage genome repertoires among banana ( Musa ) species
Published in Frontiers in microbiology (09-06-2023)“…Viruses generally cause disease, but some viruses may be beneficial as resident regulators of their hosts or host microbiomes. Plant-associated viruses can…”
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Strengthened through Diversity: A Blueprint for Organizational Change
Published in Annals of neurology (01-10-2021)Get full text
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